2013 American Transplant Congress
Role of Eosinophils in the Induction and Maintenance of the Alloantibody Response, The
Department of Medicine, Mount Sinai School of Medicine, New York
Background: Delineating mechanisms of alloantibody formation and maintenance could guide development of novel therapies aimed at treating antibody mediated transplant rejection. Published work from 2011…2013 American Transplant Congress
Factors Implicated in the Expression of Selenium Binding Protein 1 in Chronic Allograft Vasculopathy
Background: Selenium binding protein-1 (SBP-1) has been implicated in intracellular protein trafficking and secretion. In a rhesus monkey kidney transplant model we previously demonstrated that…2013 American Transplant Congress
Spectrum of Renal Pathology and Gene Expression Profiles of Kidney Biopsies in Patients with Cirrhosis Listed for Liver Transplantation
Transplantation, Montefiore Medical Center, Bronx, NY
Introduction: We previously demonstrated universal glomerular abnormalities in kidney biopsies after orthotopic liver transplantation (OLT). We hypothesize that these changes exist prior to OLT and…2013 American Transplant Congress
Where Are the Real Barriers in Post Mortem Organ Donation?
Low organ donation rate from deceased donors (DD) is believed to result from the societal misperception and non-acceptance of brain death.However, it has been shown…2013 American Transplant Congress
Unique Role of Antibodies to MHC Class I in the Induction of Inflammatory Cellular Infiltration: Selective Role for CD4 and CD8 Cells in Development of Autoimmunity and Obliterative Airway Disease
Surgery, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO
Background: Anti-MHC class I administration into lungs results in cellular infiltration, epithelial damage, immune responses to lung associated self-antigens(SAgs), KΑ1 tubulin (KΑ1T) and Collagen V…2013 American Transplant Congress
Tacrolimus Concentration Variability Is Associated with Delayed Graft Function and Diminished Renal Function in Kidney Transplant Recipients
Pharmacy, MUSC, Charleston, SC; Surgery, MUSC, Charleston, SC
Background: Tacrolimus (FK) is the drug of choice for preventing acute allograft rejection in kidney transplantation. However, therapeutic drug monitoring is necessary due to FK’s…2013 American Transplant Congress
Development of De Novo Anti-HLA Antibodies after Treatment with/without Rituximab, a B Cell−Depleting Treatment
Urology, 8-1 Kawada-Cho, Shinjuku-ku, Tokyo, Japan
Background: Organ shortages have forced a widening of the indications for kidney donors. In Japan, ABO-incompatible kidney transplantation (ABOi) is a popular alternative to deceased…2013 American Transplant Congress
Monoclonal Antibody Which Possibly May Replace the Therapeutic Intravenous Immunoglobulin, A
HLA Antibodies, Terasaki Foundation Laboratory, Los Angeles, CA
The value of intravenous immunoglobulin (IVIg) in lowering HLA antibodies (Abs) has recently come into question. High variability in different therapeutic preparations may account for…2013 American Transplant Congress
Prevalence of Human Papillomavirus (HPV) Infection in Female Kidney Transplant Recipients
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, DF, Mexico
Introduction: Kidney transplant recipients are at higher risk for viral infection-related cancers. Even though HPV infection is strongly associated with several genital cancers, data on…2013 American Transplant Congress
Tacrolimus Metabolism Rate Influences the Kidney Function after Liver Transplantation, The
Introduction: The calcineurin inhibitor (CNI) tacrolimus is a very effective immunosuppressive drug after liver transplantation (LTx) but is often associated with an impaired renal function.…
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