ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    HLA Antibody Increase Associated with Cardiac Surgery

    P. Warner, G. Aldea, M. Gallagher, K. Nelson

    Immunogenetics/HLA, Puget Sound Blood Center, Seattle, WA; Adult Cardiac Surgery, University of Washington Medical Center, Seattle, WA

    Increases in titer or de novo production of HLA antibody are potential sequelae of pregnancy, transfusion, or transplantation. It has also been reported that pro-inflammatory…
  • 2013 American Transplant Congress

    Age and Antimetabolites: Appropriate Candidate Selection Drives Success

    T. Horwedel, D. Brennan, L. Bowman

    Pharmacy, Barnes-Jewish Hospital, St. Louis, MO; Medicine, Washington University, St. Louis, MO

    Background:Early studies comparing mycophenolate (MMF) to azathioprine (AZA) post-renal transplant demonstrated superiority of MMF over AZA for the prevention of acute rejection (AR), with no…
  • 2013 American Transplant Congress

    Utility of Serial Allograft Biopsies (AGBx) during Delayed Graft Function (DGF) in Renal Transplantation, The

    H. Hatoum, A. Patel, K. Venkat

    Renal Transplant Center, Henry Ford Hospital, Detroit, MI

    Background: DGF complicates approximately 30% of deceased donor (DD) kidney transplants and rarely also occurs following live donor (LD) kidney transplants (KTX). KTX in DGF…
  • 2013 American Transplant Congress

    Using Non-Invasive, Real-Time Imaging Technology To Assess the Status of Donor Kidneys

    J. Verbesey, M. Cooper, A. Peter, R. Derek, P. Moody, Y. Chen

    MedStar Georgetown Transplant Institute, Washington, DC; Fischell Department of Bioengineering, University of Maryland, College Park, MD

    Purpose. The extent of acute tubular necrosis (ATN) in renal tubules may provide valuable prognostic data regarding post-transplant renal function of donor kidneys. We used…
  • 2013 American Transplant Congress

    Multicenter Evaluation of Efficacy and Safety of Valganciclovir 450 mg/day vs. 900 mg/day for Prevention of Cytomegalovirus Disease in Donor and Recipient Positive (D+/R+) Renal Transplant Recipients

    S. Gabardi, R. Cross, K. DePiero, T. Dick, K. Ferguson, E. Newkirk, J. Park, E. Tichy, K. Ueda, R. Weng, S. Heldenbrand

    Multicenter CMV Pharmacists Collaborative Study Group, Boston

    The cytomegalovirus (CMV) donor-positive/recipient-positive (D+/R+) population represents the largest proportion of renal transplant recipients (RTR). Current practice guidelines on the prevention of CMV recommend antiviral…
  • 2013 American Transplant Congress

    Change of Single-Kidney Glomerular Filtration Rate in Kidney Donors after Kidney Donation, The

    G. An, B. Chung, J. Kim, I. Moon, C. Park, Y. Kim, C. Yang, B. Choi

    Transplant Research Center, Seoul St. Mary's Hospital, College of Medicine,The Catholic University of Korea, Seoul, Korea; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea; Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea

    Background: It is well known that remaining nephrons after loss of renal tissue showed compensatory hyperfiltration in chronic kidney disease. But in healthy populations without…
  • 2013 American Transplant Congress

    Nutraceuticals Extenuate Kidney Ischemia/Reperfusion Injury in Rats Via HO-1 Induction

    P. Gehwolf, F. Struller, A. Kostron, M. Wolzt, B. Wegiel, J. Pratschke, R. Öllinger

    Universitätsklinik für Visceral-, Transplant- und Thoraxchirurgie, Medical University Innsbruck, Innsbruck, Austria; Universitätsklinik für Klinische Pharmakologie, Medizinische Universität Wien, Vienna, Austria; Department of Surgery, Transplant Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston

    Background: The induceable Hemeoxygenase-1 (HO-1) is the rate limiting step in the conversion of heme into biliverdin, carbon monoxide (CO) and free iron (Fe2+). Up-regulation…
  • 2013 American Transplant Congress

    Flow Crossmatching for Renal Transplantation in the Virtual Crossmatch Era: Fifty Shades of Grey

    R. Cirocco, J. Mendiolina, L. Biondi, M. Moritz

    HLA Laboratory and the Transplant Center, Lehigh Valley Health Network, Allentown, PA

    Every transplant team wants a definitive answer for the compatibility of a potential recipient with a specific donor. The Mean Equivalent Standard Fluorescence is a…
  • 2013 American Transplant Congress

    Critical Role of Notch-2 Signaling in Alloantibody Production

    C. Magee, T. Shimizu, S. Ohori, C. Siebel, N. Najafian, L. Riella

    Transplantation Research Center, Brigham & Women's Hospital, Harvard Medical School, Boston; Genentech, South San Francisco

    The role of B cells in the alloimmune response is increasingly recognized, while alloantibody production remains a major barrier to the improvement of long-term graft…
  • 2013 American Transplant Congress

    Proteinkinase C Alpha Contributes to Impairment of Renal Blood Flow and Inflammation in Hypoxia Induced Renal Ischemia Reperfusion Injury (IRI)

    D. Walacides, N. Rüskamp, R. Song, K. Hueper, M. Mengel, M. Meier, H. Haller, M. Schiffer, F. Gueler

    Nephrology, Medical School Hannover, Hannover, Germany; Radiology, Medical School Hannover, Hannover, Germany; Applied Genomics Center, University of Alberta, Edmonton, Canada; Cental Animal Facility, Medical School Hannover, Hannover, Germany

    Background – Renal ischemia reperfusion injury (IRI) leads to delayed graft function (DGF) after kidney transplantion and contributes to acute transplant rejection as well as…
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