2013 American Transplant Congress
Clinical Presentation and Outcomes of Transplant Glomerulopathy in Hepatitis C Positive Compared to Hepatitis C Negative Patients after Renal Transplantation
It has been recently reported that transplant glomerulopathy (TG) is a pattern of pathological injury. Also, hepatitis C virus infection (HCV) has been associated with…2013 American Transplant Congress
BK Polyoma Virus Infection and Efficacy of Leflunomide in Pediatric Renal Transplant Recipients
Purpose: To characterize BK virus infection and assess the efficacy of treatment strategies in pediatric renal transplant recipients.Methods: Retrospective chart review of renal transplant patients…2013 American Transplant Congress
Flt3 Ligand Induces STAT3-Independent Expansion and Activation of Myeloid-Derived Suppressor Cells Able To Promote Heart Allograft Survival
Surgery, Starzl Transplant Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA
Introduction: Fms-like tyrosine kinase 3 ligand (Flt3L) is essential for myeloid cell homeostasis, particularly dendritic cells (DC), and acts through STAT3 to promote DC expansion.…2013 American Transplant Congress
Screening for Inherited and Acquired Thrombophilia Prior to Renal Transplantation
All patients with a history of a thromboembolic event, early or recurrent vascular access thrombosis, family history of thrombosis, or multiple miscarriages underwent laboratory screening…2013 American Transplant Congress
Comparison of Baseline and Day 28 Post Transplant Renal Allograft Samples from the CTOT-10 Belatacept Study
The purpose of the CTOT-10 study is to evaluate belatacept as maintenance therapy, while minimizing calcineurin inhibitors and corticosteroids in renal transplantation. We designed mechanistic…2013 American Transplant Congress
Development of Hepatic Ischemia and Reperfusion Injury Is Independent of Myeloid Cell-Derived COX-2
David Geffen School of Medicine UCLA, Los Angeles
Cyclooxygenase-2 (COX-2) is a powerful mediator of hepatic ischemia/reperfusion injury (IRI). While COX-2 depletion significantly ameliorates liver IRI, COX-2 inhibitors present clinical limitations; Therefore, there…2013 American Transplant Congress
Mechanical Trauma Can Reactivate an Alloimmune Response Against the Skin-Component in a Large Animal Vascularized Composite Allotransplantation (VCA) Model of Operational Tolerance
Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore
BACKGROUND: The skin component of Vascularized Composite Allografts (VCA) is unique since it is directly exposed to the environment. It thereby not only offers opportunities…2013 American Transplant Congress
Mixed Acute Rejection: Comparison of Therapeutic Results with Anti-T Cell Antibody- and Proteasome Inhibitor-Based Regimens
University of Cincinnati; The Christ Hospital
Background: Mixed acute rejection (MAR) has been defined as acute rejection consisting of both cellular and humoral components. No data exist regarding MAR treatment outcomes,…2013 American Transplant Congress
Vancomycin-Resistant Enterococcus (VRE) Surgical Infection Following Liver Transplant (LT)
University of Pittsburgh, Pittsburgh
Background: VRE infection occurs in about 10% of LT patients (pts) and is associated with increased length of hospital stay and decreased survival. Some risk…2013 American Transplant Congress
Plasma Osteopontin Levels Correlate with Reversible Kidney Injury in Liver Transplant Candidates
Background: Predicting post-liver transplant (LT) recovery of renal dysfunction (RD) remains a significant clinical challenge. Biomarkers predictive of recovery would be helpful in the management…
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