Am J Transplant, Volume 22, Suppl 3 Archives - Page 92 of 190 - ATC Abstracts

2022 American Transplant Congress
Targeting the Bet Family Protein Brd4 Inhibits Inflammatory Macrophages and Promotes Heart Allograft Tolerance
X. Xiao
Surgery, Houston Methodist Hospital, Houston, TX
*Purpose: Infiltration of allografts by inflammatory macrophages is frequently associated with chronic graft loss In both animal models and clinical settings, but the mechanisms that…
2022 American Transplant Congress
Outcomes of Hlai Kidney Transplants in Patients with Cpra 100% After Desensitization
A. A. Vo¹, J. Tang¹, S. Williamson¹, C. Meyers¹, E. Huang¹, X. Zhang², M. Haas³, A. Peng¹, R. Najjar¹, S. Supreet¹, N. Ammerman¹, K. Lim¹, M. Gillespie¹, N. Badash¹, S. Jordan¹
¹Comprehensive Transplant Center, Cedars Sinai Medical Ctr, Los Angeles, CA, ²HLA Laboratory, Cedars Sinai Medical Ctr, Los Angeles, CA, ³Pathology, Cedars Sinai Medical Ctr, Los Angeles, CA
*Purpose: The KAS implementation was aimed at increasing access to kidney transplantation in highly HLA sensitized (HS) patients. However, combining desensitization (DES) + KAS could…
2022 American Transplant Congress
18 Month Impact of the National Liver Review Board
J. Foutz¹, S. Noreen¹, K. Bradbrook², M. Cafarella¹, J. Pomposelli³, S. Biggins⁴, J. Trotter⁵
¹United Network for Organ Sharing, Richmond, VA, ²Research, United Network for Organ Sharing, Richmond, VA, ³University of Colorado, Aurora, CO, ⁴University of Washington, Seattle, WA, ⁵Baylor University Medical Center, Dallas, TX
*Purpose: The National Liver Review Board (NLRB) was implemented 5/14/2019, establishing a national structure for liver exceptions comprised of three specialty review boards and a…
2022 American Transplant Congress
Delayed Graft Function in Living Donor Kidney Transplantation: Risk Factors and Outcomes
G. Defelice¹, A. Paramesh², H. Jeon², K. Atiemo², M. Killackey², A. Vijay²
¹Tulane University School of Medicine, New Orleans, LA, ²Transplant Surgery, Tulane University School of Medicine, New Orleans, LA
*Purpose: Delayed graft function (DGF) following living donor kidney transplantation is less common and long-term outcomes are less understood. This single-center retrospective analysis of living…
2022 American Transplant Congress
Comparison of Outcomes of Covid-19 Between Fully Vaccinated and Unvaccinated Kidney Transplant Recipients and According to the Type of M-RNA Vaccine
F. Villanego¹, M. Crespo², V. Lopez³, S. Zarraga⁴, F. Oppenheimer⁵, L. Llinas², A. Andres⁶, C. Diaz⁷, M. Ruiz⁸, F. Moreso⁹, A. Rodriguez-Benot¹⁰, I. Beneyto¹¹, S. Cabello¹², C. Jimenez¹³, C. Canal¹⁴, M. Molina¹⁵, J. Pascual⁶, A. Mazuecos¹
¹Department of Nephrology, Hospital Puerta del Mar, Cadiz, Spain, ²Department of Nephrology, Hospital del Mar, Barcelona, Spain, ³Department of Nephrology, Hospital Regional de Malaga, Malaga, Spain, ⁴Department of Nephrology, Hospital de Cruces, Baracaldo, Spain, ⁵Department of Nephrology, Hospital Clinic, Barcelona, Spain, ⁶Department of Nephrology, Hospital 12 de Octubre, Madrid, Spain, ⁷Department of Nephrology, Hospital Central de Asturias, Oviedo, Spain, ⁸Department of Nephrology, Hospital Virgen de las Nieves, Granada, Spain, ⁹Department of Nephrology, Hospital Vall d'Hebron, Barcelona, Spain, ¹⁰Department of Nephrology, Hospital Reina Sofia, Cordoba, Spain, ¹¹Department of Nephrology, Hospital La Fe, Valencia, Spain, ¹²Department of Nephrology, Hospital Son Espases, Palma de Mallorca, Spain, ¹³Department of Nephrology, Hospital La Paz, Madrid, Spain, ¹⁴Department of Nephrology, Fundacion Puigvert, Barcelona, Spain, ¹⁵Department of Nephrology, Hospital Germans Trias i Pujol, Badalona, Spain
*Purpose: The evidence regarding the clinical effectiveness of COVID-19 vaccination in kidney transplant (KT) recipients is limited so far. Our purpose is to analyze the…
2022 American Transplant Congress
Identification of a Human B Cell State with Allogeneic Antigen Cross-Presenting Potential
U. Bhatia, E. C. Guinan
Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA
*Purpose: B cells are known to play a significant role in allograft tolerance or rejection, largely determined by production of cytokines and antibodies that suppress…
2022 American Transplant Congress
Long-Term Insulin Independence Achieved by a Multimodal Approach to Beta-Cell Replacement in Patients with Type I Diabetes
M. Nunez¹, S. Wisel², J. Gardner³, G. Worner⁴, G. Roll⁵, S. Syed³, G. Szot¹, M. Tavakol¹, K. Johnson¹, A. Posselt⁴, P. Stock⁶
¹Surgery, University of California, San Francisco, San Francisco, CA, ²Cedars-Sinai Medical Center, Los Angeles, CA, ³University of California, San Francisco, San Francisco, CA, ⁴University of California San Francisco, San Francisco, CA, ⁵UCSF Medical Center, San Francisco, CA, ⁶Univ of California-San Francisco, San Francisco, CA
*Purpose: Long-term insulin independence in beta-cell replacement, via islet or pancreas transplant, remains limited by the toxic effects of calcineurin inhibitors (CNI) on beta cells…
2022 American Transplant Congress
Impact of MMaT Policy on Transplant for Hepatocellular Carcinoma at a Single Center
S. Kodali¹, D. W. Victor², J. Corkrean², A. Shetty², C. Mobley², M. Hobeika², R. McMillan², E. A. Graviss³, D. T. Nguyen³, R. McFadden⁴, V. Ankoma-Sey², C. Egwim⁵, J. Galati², A. Saharia², R. M. Ghobrial²
¹Sherrie and Alan Conover Center for Liver Disease and Transplantation, Houston Methodist Hospital, Sugarland, TX, ²Sherrie and Alan Conover Center for Liver Disease and Transplantation, Houston Methodist Hospital, Houston, TX, ³Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, ⁴Department of Medicine, Hepatology, Houston Methodist Hospital, Houston, TX, ⁵Houston Methodist Hospital, Houston, TX
*Purpose: Hepatocellular carcinoma (HCC) is the most common primary malignant hepatic tumor. Currently, liver transplantation may be the optimal treatment for HCC. Patient selection criteria…
2022 American Transplant Congress
De Novo Lipoprotein-X Causing Hypercholesterolemia and Acute Kidney Injury (AKI) in Simultaneous Liver Kidney Transplant (SLKT) Patient
H. Me, S. S. Nair, M. Al-Qaisi, M. Ryan, L. Kodali, B. Aqel
Mayo Clinic, Phoenix, AZ
*Purpose: Cholestasis can cause reflux and spillage of biliary lipid into the plasma which can combine with albumin forming lipoprotein-X. Severe hypercholesterolemia mediated by lipoprotein-X…
2022 American Transplant Congress
Unravelling the Stage-Shift of Acute Rejection by Urine QSant
W. Yazar¹, N. Titzler¹, R. Sarwal¹, M. Sarwal², S. Ghosh¹
¹Nephrosant, Brisbane, CA, ²NephroSant, Brisbane, CA
*Purpose: Suboptimal performance in current methods for allograft monitoring underscores the unmet need for enhanced immunosurveillance accuracy, to uncover the alloimmunity flux. QSant[Yang et al,…