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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Covid-19 Vaccination Response In Tacrolimus Treated Kidney Transplant Recipients With And Without Mycophenolate Mofetil: Follow-up Of A Randomized Controlled Trial

    Z. Al Fatly1, M. G. Betjes1, A. L. Messchendorp2, J. S. Sanders2, M. E. Reinders1, M. M. Kho1, A. E. de Weerd1

    1Department of Internal Medicine, Erasmus MC Transplant Institute University Medical Center, Rotterdam, Netherlands, 2Department of Internal Medicine, Groningen Medical Center, Groningen, Netherlands

    *Purpose: To investigate the effect of mycophenolate mofetil (MMF) on SARS-CoV-2 vaccination response in kidney transplant recipients using the standard immunosuppressive regimen of tacrolimus (TAC)…
  • 2022 American Transplant Congress

    Socioeconomic Deprivation of “Closed for No Contact” Kidney Transplant Referrals

    S. Cooley1, D. Cassidy2, N. Kunnath3, R. Sung4, V. S. Valbuena4

    1Kansas City University of Medicine, Kansas City, MO, 2University of Michigan Medical School, Ann Arbor, MI, 3Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, 4Department of Surgery, University of Michigan, Ann Arbor, MI

    *Purpose: The kidney transplant process has a high attrition rate. Socioeconomic factors have been associated with low evaluation completion. After a referral is placed for…
  • 2022 American Transplant Congress

    Degree of Pre-Liver Transplant Immune Dysfunction Correlates with Post-Transplant Cancer Recurrence

    G. S. Prakash1, G. G. Panayotova1, S. Simonishvili1, Y. Qin1, L. Jin1, T. Ayorinde1, L. J. Minze2, F. Paterno1, L. Brown1, A. Amin1, D. Liu1, R. Ghobrial2, J. V. Guarrera1, K. E. Lunsford1

    1Rutgers New Jersey Medical School, Newark, NJ, 2Houston Methodist Hospital, Houston, TX

    *Purpose: Despite stringent selection criteria for liver transplant (LT) in patients with liver-limited malignancy, post-transplant cancer recurrence remains problematic. We have previously identified a pre-LT…
  • 2022 American Transplant Congress

    Infection Impacts dd-cfDNA in Lung Transplant Recipients

    D. Levine1, C. Giner1, C. Pham2, R. Woodward2, A. Roux3

    1University of Texas Health System San Antonio, San Antonio, TX, 2CareDX, South San Francisco, CA, 3Pneumology, Adult CF Center and Lung Transplantation Department, Foch Hospital, Suresnes, France

    *Purpose: Infection is the leading cause of death within 1 year post lung transplant. Graft injury secondary to infection is affected by both source and…
  • 2022 American Transplant Congress

    Kidney Transplantation in Patients Postradical Prostatectomy

    S. Karhadkar, K. Wirshup, J. Kolansky, A. Gregor, J. Dawes, A. DiCarlo

    Temple University Hospital, Philadelphia, PA

    *Purpose: The population of the United States is aging. By the year 2050 those over 65 years of age are projected to make up 20.2%…
  • 2022 American Transplant Congress

    Prolonged Xeno-Kidney Graft Survival in Highly Allo-Sensitized Nonhuman Primate Using Triple-Knockout Donor Pigs with 7 Human Transgenes

    M. Manook1, D. Olaso1, I. Anwar1, J. Yoon1, M. Song1, A. B. Farris2, K. Stiede3, K. Hall3, M. Youd3, S. Knechtle1, J. Kwun1

    1Surgery, Duke Transplant Center, Durham, NC, 2Pathology, Emory University, Atlanta, GA, 3eGenesis Inc, Cambridge, MA

    *Purpose: We have previously shown using porcine kidneys from genetically modified knockout alpha 1,3-galactosyltransferase (GGTA1KO) and human decay accelerating factor transgenic (CD55Tg) pigs that compared…
  • 2022 American Transplant Congress

    Phase I/ii Car-Treg Cell Therapy Clinical Trial To Induce Long-term Tolerance In Liver Transplant Patients

    A. Sanchez-Fueyo1, A. Taylor1, D. Collin2, C. Nathalie2, S. Chris2, M. Martinez-Llordella2, N. Belmonte2, I. McGill2, D. Hartl2

    1King's College London, London, United Kingdom, 2Quell Therapeutics Ltd, London, United Kingdom

    *Purpose: Life-long pharmacological immunosuppression (IS) is considered essential to prevent rejection following liver transplantation (LT), but is associated with significant side effects such as infections,…
  • 2022 American Transplant Congress

    Establishing a Framework for Long-Term Follow-Up: A Survey of Perspectives and Preferences of Living Kidney Donors

    S. K. Singh1, N. Caton2, O. Johnston2, C. S. Hanson3, A. Dominello3, K. Yetzer4, D. Chang2, A. Tong3, J. S. Gill2

    1Department of Medicine, University of Toronto, Toronto, ON, Canada, 2Department of Medicine, University of British Columbia, Vancouver, BC, Canada, 3Sydney School of Public Health, University of Sydney, Sydney, Australia, 4Canadian Blood Services, Ottawa, ON, Canada

    *Purpose: There is currently no established standard for long-term follow-up of living kidney donors in Canada. To inform a new national standard, we sought to…
  • 2022 American Transplant Congress

    Predictors of Response to Belatacept Conversion in Kidney Transplant Patients with Chronic Active Antibody-Mediated Rejection

    D. Kumar1, R. Winstead1, H. Iftikhar1, R. Minniti1, S. Khorsandi1, J. Christensen1, I. Yakubu1, I. Moinuddin1, L. Kamal1, P. Halloran2, G. Gupta1

    1Virginia Commonwealth University, Richmond, VA, 2University of Alberta, Edmonton AB, AB, Canada

    *Purpose: Chronic active antibody mediated rejection (cABMR) is a major cause of kidney transplant (KT) loss. Current therapies have unclear efficacy and side effects. We…
  • 2022 American Transplant Congress

    Variation in Adult Living Donor Liver Transplantation in the United States: Identifying Opportunities for Increased Utilization

    K. Lentine1, D. Axelrod2, M. Schnitzler1, R. Li1, M. Dew3, T. Bitterman4, K. Olthoff4, J. Locke5, S. Emre6, H. Hunt7, T. Tanaka2, A. Liapakis6

    1Saint Louis University, St. Louis, MO, 2U Iowa, Iowa City, IA, 3U Pittsburgh, Pittsburgh, PA, 4U Penn, Philadelphia, PA, 5UAB, Birmingham, AL, 6Yale, New Haven, CT, 7UNOS, Richmond, VA

    *Purpose: To assess barriers to living donor liver transplant (LDLT) access in light of convincing evidence of survival benefits for patients with end-stage liver disease.*Methods:…
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