ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Type 1 Natural Killer T-cells: Key Mediators of Ischemia- Reperfusion Injury in Hepatic Steatosis

    J. R. Liggett1, J. Kang1, K. Loh1, K. Oza1, Y. Cui1, D. Kwon2, H. Li3, B. Kallakury2, T. Fishbein1, W. Cui1, K. Khalid1, A. H. Kroemer1

    1MedStar Georgetown Transplant Institute, Washington, DC, 2Pathology, MedStar Georgetown University Hospital, Washington, DC, 3Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC

    *Purpose: Hepatic ischemia-reperfusion injury (IRI) poses a significant risk in liver transplantation and hepatic resection and is further exacerbated by hepatic steatosis. Type 1 Natural…
  • 2022 American Transplant Congress

    Improving Efficiency in Kidney Distribution: A Comparison of UNet Deceased Donor Criteria to Actual Kidney Acceptance Practices

    L. B. Zeiser, J. Ruck, D. Segev, A. Massie

    Johns Hopkins University, Baltimore, MD

    *Purpose: Efficient utilization of UNet deceased-donor criteria could help streamline kidney allocation by reducing the number of unwanted offers made to transplant centers. We compared…
  • 2022 American Transplant Congress

    Baseline Trends in Tacrolimus Intrapatient Variability in Pediatric and Young Adult Kidney Transplant Recipients

    K. Piburn1, L. Maestretti2, M. V. Patton2, A. M. McGrath2, O. S. Indridason3, A. Chaudhuri1, P. Grimm1, V. Sigurjonsdottir1

    1Pediatric Nephrology, Stanford University, Palo Alto, CA, 2Pediatric Kidney Transplant, Lucile Packard Children's Hospital, Palo Alto, CA, 3Division of Nephrology, Landspitali – the National University Hospital of Iceland, Reykjavik, Iceland

    *Purpose: High tacrolimus intrapatient variability (IPV) is a known risk factor for poor graft outcomes in kidney transplantation. Baseline trends in tacrolimus IPV have not…
  • 2022 American Transplant Congress

    Physicians Are Perfectionists and Patients Are Pragmatic? Comparing Physician and Patient Definitions of Success in Liver Transplantation

    I. Woelfel1, D. Faulkner1, W. Kellett1, K. Washburn2, A. Schenk1

    1Ohio State University, Columbus, OH, 2The Ohio State University, Columbus, OH

    *Purpose: The purpose of this study was to compare and contrast patient and physician perceptions of success one year after liver transplantation.*Methods: This was a…
  • 2022 American Transplant Congress

    Single Center Experience with Acute Kidney Injury Deceased Donor Kidneys from Marginal Donors

    B. K. Sharda, M. Garner, A. Farney, G. Orlando, C. Jay, J. Rogers, A. Daniel, A. Gutierrez, N. Sakhovskaya, R. Stratta

    Atrium Health Wake Forest Baptist Medical Center, Winston Salem, NC

    *Purpose: Many centers will selectively transplant kidneys from standard criteria donors (SCD) with terminal acute kidney injury (AKI). However, there is limited experience with transplanting…
  • 2022 American Transplant Congress

    Nebulized Mitochondria Localize to Transplanted Allografts and Improve Outcomes Following Lung Transplantation

    D. Nord1, Z. Tu2, L. Langerude1, A. McQuiston1, J. Kwon3, S. Nadig4, T. Machuca5, C. Atkinson1

    1Pulmonary Medicine, University of Florida, Gainesville, FL, 2University of Florida, Gaineville, FL, 3MUSC College of Medicine, Charleston, SC, 4Northwestern University, Charleston, SC, 5Department of Surgery, University of Florida, Gainesville, FL

    *Purpose: Mitochondrial transplantation therapy is an innovative strategy for the treatment of mitochondrial dysfunction. The approach has shown efficacy in the treatment of cardiac ischemic…
  • 2022 American Transplant Congress

    HDAC6 Inhibition Mediated Protection from Hepatic Ischemia Reperfusion is Associated with Preserved Glutathione Levels

    C. OBrien1, P. Hernandez1, S. Concors2, Z. Wang1, G. Ge3, A. Kozikowski4, W. Hancock5, M. Levine2

    1Surgery, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Surgery, University of Pensylvania, Philadelphia, PA, 4College of Pharmacy, University of Illinois at Chicago, Chicago, IL, 5Childrens Hospital of Philadelphia, Philadelphia, PA

    *Purpose: Liver Ischemia reperfusion injury (IRI) and Acetaminophen (APAP) toxicity are important causes of acute liver failure in the United States, that lack effective therapy.…
  • 2022 American Transplant Congress

    Parainfluenza Type 3 Infection in Solid Organ Transplant Recipients

    G. Motoa1, M. A. Mendoza1, M. Raja1, J. Simkins2, S. Anjan2, E. Martin2, A. Phancao2, N. Sinha2, L. Abbo1, G. Guerra2, Y. Natori2

    1University of Miami/Jackson Memorial Hospital, Miami, FL, 2Miami Transplant Institute – University of Miami, Miami, FL

    *Purpose: Respiratory viral infection, including COVID-19, causes significant morbidity and mortality in solid organ transplant recipients (SOTR), however, the data of parainfluenza virus (PIV) type…
  • 2022 American Transplant Congress

    En-Bloc Kidney Transplantation in Children Over a 33-year Period in USA – A Comparative Study

    P. Gogalniceanu1, I. D. Kostakis2, P. Chandak3, G. Papadakis4, J. Stojanovic5, F. Calder4, I. Loukopoulos4, N. Kessaris4

    1Abdominal Transplant Surgery, Guy's Hospital, London, London, United Kingdom, 2Department of HPB Surgery and Liver Transplantation, Royal Free Hospital, Royal Free London NHS Foundation Trust, London, United Kingdom, 3Transplantation, Guy's and St Thomas Hospitals NHS Trust and King's College London, London, United Kingdom, 4Guy's Hospital, London, United Kingdom, 5Great Ormond Street Hospital, London, United Kingdom

    *Purpose: En-bloc kidney transplantation is not commonly performed due to scarcity of such organs as well as due to potential technical and thrombotic problems. We…
  • 2022 American Transplant Congress

    Why and How We Do Native Nephrectomy in Low Weight Pediatric Kidney Transplantation Patients

    N. Celik1, B. Akyollu1, E. Arpali1, N. Akinci2, I. Bilge2, B. Kocak1

    1Division of Organ Transplantation, Koc University Hospital, Istanbul, Turkey, 2Division of Pediatric Nephrology, Koc University Hospital, Istanbul, Turkey

    *Purpose: There is no consensus about optimal timing for native nephrectomy according to the primary indication of kidney transplantation (KTx) especially in pediatric population and…
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