Am J Transplant, Volume 22, Suppl 3 Archives - Page 57 of 190 - ATC Abstracts

2022 American Transplant Congress
Prediction of ESRD Risk in Living Kidney Donors Through Thirty Years Post-Donation
A. Massie¹, J. Snyder², M. Levan¹, D. Brennan¹, F. Al-Ammary¹, D. Segev¹
¹Johns Hopkins, Baltimore, MD, ²Scientific Regristry of Transplant Recipients, Minneapolis, MN
*Purpose: Living kidney donors face increased risk of ESRD, although absolute risk remains low through 20 years postdonation. Informed consent for kidney donation depends on…
2022 American Transplant Congress
Changes in Diastolic Function and Cardiac Geometry After Pediatric Kidney Transplant: A Longitudinal Study
K. Sgambat¹, S. Clauss², A. Moudgil¹
¹Nephrology, Children's National Hospital, Washington DC, DC, ²Cardiology, Children's National Hospital, Washington DC, DC
*Purpose: Kidney transplant recipients are at increased risk for cardiovascular disease but systolic function is often preserved and may not reveal cardiac dysfunction until it…
2022 American Transplant Congress
Renal Failure is Reversible in the Majority of Patients Transplanted for Alcohol-Associated Hepatitis: A Review of the UNOS Database
Y. Bekki, G. Im, T. Schiano, S. Florman
Icahn School of Medicine at Mount Sinai, RMTI, New York, NY
*Purpose: The simultaneous liver-kidney (SLK) allocation policy in 2017 created Safety Net kidney allocation priority for liver transplant (LT) recipients with renal failure. Renal failure…
2022 American Transplant Congress
Post Heart Transplant Outcomes of Desensitized Durable Mechanical Circulatory Support Patients
J. Youn¹, D. Kim², J. Choi², K. Kim¹, I. Kim³, E. Kransdorf⁴, D. Chang⁴, M. Kittleson⁴, J. Patel⁴, R. Cole⁴, J. Moriguchi⁴, D. Ramzy⁵, F. Esmailian⁵, J. A. Kobashigawa⁴
¹Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea, Republic of, ²Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, ³Keimyung University Dongsan Hospital, Daegu, Korea, Republic of, ⁴Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Department of Cardiothoracic Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Desensitization therapy (DST) is considered to increase the chances of a negative crossmatch, to expand the number of suitable donors, and to improve post-transplant…
2022 American Transplant Congress
COVID-19 in Solid Organ Transplant: A Global Perspective
.. C19TxR Consortium
ESOT, NHSBT, UNOS, CareDx, South San Francisco, CA
*Purpose: Transplantation has been disrupted dramatically by COVID-19 due to reallocation of healthcare resources and concerns from early reports of increased mortality rates (20-30%) in…
2022 American Transplant Congress
Pancreatic Islets Engineered with Thrombomodulin Show Enhanced Engraftment in an Intraportal Transplantation Model by Mitigating Instant Blood-Mediated Inflammatory Reactions
A. Turan¹, L. Zhang², M. Tarique², V. Ulker², E. Yolcu³, H. Shirwan³
¹Molecular Microbiology and Immunology, University of Missouri at Columbia, Columbia, MO, ²Department of Child Health, University of Missouri at Columbia, Columbia, MO, ³Child Health and Molecular Microbiology and Immunology, University of Missouri at Columbia, Columbia, MO
*Purpose: IBMIR is a major culprit of early islet loss post-transplant. Thrombomodulin (TM) is an anti-coagulant and cofactor of activated Protein C (APC) that perpetuates…
2022 American Transplant Congress
Role of Mitochondrial Transplantation in Enhancing Liver Regeneration Following Partial Hepatectomy
G. Lamanilao¹, C. Watkins¹, C. Kuscu¹, C. Kuscu¹, J. Eason², A. Bajwa¹
¹Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, ²University of Tennessee/Methodist Transplant Institute, Memphis, TN
*Purpose: Therapeutic strategies that accelerate the rate of liver regeneration following partial hepatectomy (PH) should be developed to reduce occurrences of small for size syndrome…
2022 American Transplant Congress
Implementing Clinical Decision Support Tools for Immunosuppressant Drug-Drug Interactions to Prevent Graft Failure
A. Yishak¹, S. Ledan², S. Mukherjee³, C. Chen², A. Ayoola², T. Kim², A. Olenik², K. Mullican², A. Henje², N. Lorence², L. Beckman²
¹MAPMG, Mc Lean, VA, ²Kaiser Permanente, Silver Spring, MD, ³MAPMG, Rockville, MA
*Purpose: Immunosuppressant drug-drug interactions can result in immunosuppressant toxicity or subtherapeutic levels causing rejection. If not identified and managed appropriately, these interactions may result in…
2022 American Transplant Congress
Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Porcine Pancreas Grafts
C. Parmentier, S. Ray, L. Mazilescu, M. Kawamura, T. Goto, Y. Noguchi, B. Arulratnam, S. Ganesh, M. Selzner, T. Reichman
Multi-Organ Transplant Department, University Health Network - Toronto General Hospital, Toronto, ON, Canada
*Purpose: The purpose of this study was to develop a stable porcine model for normothermic ex-vivo pancreas perfusion (NEVPP) for the preservation of grafts with…
2022 American Transplant Congress
Sirolimus Use Is Associated With An Improved Immune Response To Covid-19 Vaccination In Kidney Transplant Recipients
G. B. Perkins¹, M. Tunbridge², T. Salehi², C. Chai¹, C. M. Hope¹, P. Garcia-Valtanen¹, J. J. Singer³, P. R. Hurtado², S. C. Barry¹, B. Grubor-Bauk¹, P. Hissaria², S. J. Chadban³, P. Coates¹
¹University of Adelaide, Adelaide, Australia, ²Royal Adelaide Hospital, Adelaide, Australia, ³Royal Prince Alfred Hospital, Sydney, Australia
*Purpose: Kidney transplant recipients (KTRs) are highly vulnerable to severe COVID-19, however are poorly protected by vaccination. Additional vaccine doses have achieved limited improvements in…