ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Clusterin Protects Kidney Transplants from Ischemia-Reperfusion Injury by Modulating Neutrophil Infiltration

    Y. Shim1, R. Fan2, N. Dvorina2, K. McCrae1, B. William2

    1Cardiovascular and Metabolic Sciences, Cleveland Clinic Lerner Research Institute, Cleveland, OH, 2Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, OH

    *Purpose: Ischemia-reperfusion injury (IRI) is inevitable during organ transplantation. Clusterin (CLU) has shown to be protective in IRI. Supplementation of storage solution with recombinant CLU…
  • 2022 American Transplant Congress

    Axl and MerTK Regulate the Activation of Liver Ischemia Reperfusion Injury by Upregulating Il-13 in Kupffer Cells

    J. Zhang1, M. Ni1, H. Zhang1, R. Busuttil1, J. Kupiec-Weglinski1, X. Wang2, J. Jin3, Y. Zhai1

    1Dumont-UCLA Transplant Center, Los Angeles, CA, 2The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 3Guilin Medical University, Guilin, China

    *Purpose: Ischemia reperfusion injury (IRI) remains an unresolved clinical problem. A sterile inflammatory response drives the disease pathogenesis. Although mechanisms of liver innate immune activation…
  • 2022 American Transplant Congress

    Risk Factors Associated with ICU Admission and Death in Patients Hospitalized with COVID-19 Differ Between Solid Organ Transplant and Non-Solid Organ Transplant Patients

    J. Schaenman, H. Byford, T. R. Grogan, Y. Motwani, O. Beaird, M. Kamath, E. Lum, K. Meneses, D. Sayah, D. Vucicevic, S. Saab

    David Geffen School of Medicine at UCLA, Los Angeles, CA

    *Purpose: Despite the large numbers of reports on patient risk factors for poor clinical outcomes with COVID-19, little is known about how these risks may…
  • 2022 American Transplant Congress

    Recurrent Cytomegalovirus and the Role of Secondary Prophylaxis in Heart and Lung Transplant Recipients

    S. N. Finder1, K. Harrison1, M. Morrison1, S. Rega2, I. Feurer2, C. Gorsline3, G. Satyanarayana3, S. Hamel1

    1Department of Pharmaceutical Sciences, Vanderbilt University Medical Center, Nashville, TN, 2Vanderbilt Transplant Center, Nashville, TN, 3Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN

    *Purpose: This study aimed to describe the incidence of cytomegalovirus (CMV) recurrence in heart and lung transplant recipients and the effect of secondary prophylaxis (SP)…
  • 2022 American Transplant Congress

    The US Kidney Allocation System Should Not Allocate En Bloc Kidneys from Deceased Donors < 18 Kg as Equivalent to Top 20% KDPI Single Kidneys

    W. F. Parker1, A. Gallo2, L. Ross1

    1University of Chicago, Chicago, IL, 2Stanford University, Palo Alto, CA

    *Purpose: In December 2020, the US Kidney Allocation System (KAS) revised the allocation rules for deceased donors under 18 kg, stating that both kidneys must…
  • 2022 American Transplant Congress

    Final Flow and Resistance During Cold Pulsatile Perfusion Preservation Do Have Value in Prediction of Deceased Donor Graft Survival After Adjusting for KDPI

    D. S. Keith, E. Lessmann

    Kidney Transplant, Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine whether cold pulsatile perfusion preservation (CPPP) parameters of flow and resistance provide additional data regarding deceased donor kidney graft survival after adjusting…
  • 2022 American Transplant Congress

    Bisphosphonates for Fracture Prevention in Kidney Transplant Recipients

    J. Kahwaji1, S. Yang2, J. Sim3

    1Nephrology/Transplant, Kaiser Los Angeles Medical Center, Los Angeles, CA, 2Research and Evaluation, Kaiser-Permanente, Pasadena, CA, 3Nephrology, Kaiser Los Angeles Medical Center, Los Angeles, CA

    *Purpose: Kidney transplant recipients are at increased risk of fracture, however bisphosphonate use has not be shown to lower fracture risk in this population. We…
  • 2022 American Transplant Congress

    Prevalence of Mycophenolate Mofetil (MMF) Discontinuation and Outcomes in Pediatric Kidney Transplants (PKTX): A PNRC Study

    A. Moudgil1, K. Sgambat1, E. Benoit2, A. Jain3, M. Seifert4, C. Katsoufis5, L. Harshman6, A. Mansuri7, M. Somers8

    1Nephrology, Children's National Med. Ctr., Washington, DC, 2Nephrology, Boston's Children's Hospital, Boston, MA, 3Nephrology, Wayne State University, Troy, DC, 4Nephrology, The University of Alabama, Birmingham, AL, 5Nephrology, Holtz Children's Hospital, Miami, FL, 6Nephrology, University of Iowa, Iowa City, IA, 7Nephrology, Children's Hospital of Georgia, Augusta, GA, 8Nephrology, Boston Children's Hospital, Boston, MA

    *Purpose: MMF is discontinued in PKTX for various reasons. In this Pediatric Nephrology Research Consortium (PNRC) study, we determined prevalence and reasons for MMF discontinuation…
  • 2022 American Transplant Congress

    Performance of Kidney Transplantation in a Resource-Poor Setting of Southeast Nigeria- A Review of the First Ten Cases

    C. G. Okwuonu1, O. J. Chimezie2, G. O. Achor3, N. M. Erondu4, C. Ralph-Iheke5, S. Alhassan6

    1INTERNAL MEDICINE/NEPHROLOGY, Federal Medical Centre, Umuahia, Nigeria, 2OPTOMETRY, Federal Medical Centre, Umuahia, Nigeria, 3SURGERY/UROLOGY, Federal Medical Centre, Umuahia, Nigeria, 4ANAESTHESIA, Federal Medical Centre, Umuahia, Nigeria, 5NURSING SERVICES DIVISION, Federal Medical Centre, Umuahia, Nigeria, 6SURGERY/UROLOGY, Aminu Kano Teaching Hospital, Kano, Nigeria

    *Purpose: To assess complication and survival after performance of kidney transplantation in a resource poor setting in Southeast Nigeria*Methods: A retrospective review of transplant registers…
  • 2022 American Transplant Congress

    Hard to Place Dual Kidney Transplantation (HTPDKT): A Viable Option Despite Prolonged Cold Ischemia

    R. Plews1, E. Siskind2, M. Laftavi2, E. Shipman3, S. Shah2, D. Conti4, A. Adekile2, S. Nijim2, S. K. Patel2

    1Albany Medical College, Albany, NY, 2Center for Transplantation, University Medical Center of Southern Nevada, Las Vegas, NV, 3Nevada Donor Network, Las Vegas, NV, 4Albany Medical Center, Albany, NY

    *Purpose: Less than perfect kidneys are often difficult to place in the current kidney allocation system. The kidneys have to travel extended distances , increasing…
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