ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Cmv-Specific Cell-Mediated Immune Reconstitution in High-Risk Hematopoietic Cell Transplant Recipients Receiving Letermovir Prophylaxis

    M. Z. Abidi1, K. Garth1, J. Gutman2, A. Weinberg1

    1Medicine, Infectious Disease, University of Colorado, Aurora, CO, 2Medicine, Hematology and Oncology, University of Colorado, Aurora, CO

    *Purpose: In the absence of antiviral prophylaxis following Hematopoietic Cell Transplant (HCT), the incidence of clinically significant cytomegalovirus reactivation (cCMV) is 30% in CMV seropositive…
  • 2022 American Transplant Congress

    Social Determinants of Health Impact Successful Listing for Liver and Kidney Transplant

    J. B. Henson, D. Mohottige, J. M. Wilder, A. J. Muir, L. M. McElroy

    Duke University, Durham, NC

    *Purpose: To evaluate the association between community socioeconomic disadvantage and structural social determinants of health (SDOH) on successful listing for liver (LT) and kidney transplantation…
  • 2022 American Transplant Congress

    Presence of Infiltrating Regulatory T Cells in the Cardiac Xenografts and Their Potential Role in Graft Survival

    A. K. Singh1, C. E. Goerlich1, G. Braileanu1, A. Hershfeld1, T. Zhang1, I. Tatarov1, B. Lewis1, F. Sentz1, D. Ayares2, B. Griffith1, M. M. Mohiuddin1

    1Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, 2Revivicor Inc, Blacksburg, WV

    *Purpose: Regulatory T (CD4+CD25HiFoxP3+) cells (Treg) are a very small subset of CD4+ T cells that have been shown to play an important role in…
  • 2022 American Transplant Congress

    Early Clinical Experience With Nirmatrelvir/ritonavir For Treatment Of Covid-19 In Solid Organ Transplant Recipients

    D. Salerno1, D. Jennings2, N. Lange3, D. Kovac1, T. Shertel1, J. Chen4, J. Hedvat5, J. Scheffert1, R. S. Brown6, M. Pereira7

    1NewYork-Presbyterian Hospital, New York, NY, 2Long Island University, Brooklyn, NY, 3Pharmacy, NewYork-Presbyterian Hospital, New York, NY, 4Columbia University Irving Medical Center, Fort Lee, NJ, 5New York Presbyterian Hospital, Tenafly, NJ, 6Weill Cornell Medicine, New York, NY, 7New York Presbyterian Hospital, New York, NY

    *Purpose: Nirmatrelvir/ritonavir use has not yet been described in solid organ transplant recipients (SOTR) who become infected with COVID-19. The objective of our study was…
  • 2022 American Transplant Congress

    Non-HLA Antibodies to G Protein-Coupled Receptors and Allograft Survival in Pediatric Kidney Transplant Recipients: Short- and Long-Term Outcomes

    M. Pearl1, L. Chen1, P. Weng1, E. T. Chambers2, E. F. Reed3

    1UCLA, Los Angeles, CA, 2Pediatrics, Duke University, Durham, NC, 3Univ of California LA, Los Angeles, CA

    *Purpose: We have recently shown that the non-HLA antibodies to angiotensin II type 1 receptor (AT1R-Ab) and endothelin-1 type A receptor (ETAR-Ab) are prevalent and…
  • 2022 American Transplant Congress

    Liver Transplantation in Patients with Portal Vein Thrombosis: Implications and Outcomes

    D. Noguchi, C. J. Rosenthal, M. Ha, V. G. Agopian, D. G. Farmer, F. M. Kaldas

    Liver and Pancreas Transplant Center, UCLA, Los Angeles, CA

    *Purpose: Preoperative bland portal vein thrombosis (PVT) is common in Liver transplant (LT) candidates and has been suspected to negatively impact post-LT outcomes, however studies…
  • 2022 American Transplant Congress

    Effect of Covid-19 Vaccination on Markers of Rejection in Heart Transplant Recipients

    Z. Pieters1, E. Bruno1, S. Kim1, S. De Sirkar1, M. Thomas1, S. B. Sharmin2, M. Liebo1, A. Heroux1, N. Clark1, G. Reid1, S. Uprichard2, M. Yu1

    1Medicine, Loyola University Medical Center, Maywood, IL, 2Loyola University Chicago, Chicago, IL

    *Purpose: Heart transplant recipients have worse survival with COVID-19 than the general population, highlighting the importance of vaccination in these patients. The impact of vaccination…
  • 2022 American Transplant Congress

    Trends in Prescribing Gabapentinoids, Co-Prescribed with Opioids or Benzodiazepines Among Kidney Transplant Recipients

    J. Ahn1, S. Bae1, J. Kim1, M. Schnitzler2, G. Hess3, K. Lentine2, D. Segev1, M. McAdams-DeMarco1

    1Johns Hopkins University, Baltimore, MD, 2Saint Louis University, St. Louis, MO, 3Drexel University, Philadelphia, PA

    *Purpose: Gabapentinoid are commonly used to manage neuropathic pain in recipients with kidney transplantation (KT), with increasing concerns of co-prescribing with opioids and benzodiazepines leading…
  • 2022 American Transplant Congress

    Long-Term Rejection Free Renal Allograft Survival with Fc-Modified Anti-cd154 Antibody Monotherapy in Nonhuman Primates

    G. Lassiter, T. Hirose, A. D’Attilio, T. Kawai

    MGH Center for Transplantation Sciences, Boston, MA

    *Purpose: Belatacept is currently the only FDA approved costimulatory blockade (CB) used as an alternative to calcineurin inhibitors in kidney transplantation. However, it has been…
  • 2022 American Transplant Congress

    Human PBMC-Transferred Murine MHC Class I/II-Deficient NOG Mice Enable Long-Term Evaluation of Human Immune Responses to Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Sheets

    R. Matsumoto

    Center for Immune Therapeutics and Diagnosis, Juntendo University, Tokyo, Japan

    *Purpose: Transplantation of cardiomyocytes sheets derived from allogenic human induced pluripotent stem cells (hiPS-CMs) hold great promise in generating new functional myocardium in situ. However,…
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