ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Early Experience with Varicella Vaccination in Pediatric Heart Transplant Recipients

    A. Dipchand, M. Seifert-Hansen

    The Hospital of Sick Children, Toronto, ON, Canada

    *Purpose: International consensus guidelines to vaccinate children after transplant with varicella (VZV) vaccine exclude heart recipients due to insufficient evidence for safety, seroconversion rate, and…
  • 2022 American Transplant Congress

    Moral Distress Among Palliative Care and Transplant Clinicians in the Context of Transplant Care

    K. Ladin1, E. Park2, J. Perugini2, K. Aufort2, T. Porteny2

    1Tufts University, Medford, MA, 2REACH Lab, Tufts University, Medford, MA

    *Purpose: Despite benefits of palliative care referrals and early advance care planning for patients with end-stage organ disease and recipients experiencing graft failure, few patients…
  • 2022 American Transplant Congress

    DEPTOR: A Novel Endothelial-Specific Regulator of Cell-Intrinsic Anti-Inflammation Following Transplantation

    C. Testini1, S. Bose1, K. Liu1, S. Kong1, E. Flynn1, M. Miovski1, J. Leyva-Rangel1, M. Laplante2, J. Wedel1, D. M. Briscoe1

    1Boston Children's Hospital and Harvard Medical School, Boston, MA, 2Laval University, Quebec, QC, Canada

    *Purpose: Recent studies have highlighted a paradigm whereby the maintenance of normal tissue homeostasis and the prevention of chronic inflammation is dependent on the active…
  • 2022 American Transplant Congress

    Prediction of ESRD Risk in Living Kidney Donors Through Thirty Years Post-Donation

    A. Massie1, J. Snyder2, M. Levan1, D. Brennan1, F. Al-Ammary1, D. Segev1

    1Johns Hopkins, Baltimore, MD, 2Scientific Regristry of Transplant Recipients, Minneapolis, MN

    *Purpose: Living kidney donors face increased risk of ESRD, although absolute risk remains low through 20 years postdonation. Informed consent for kidney donation depends on…
  • 2022 American Transplant Congress

    Changes in Diastolic Function and Cardiac Geometry After Pediatric Kidney Transplant: A Longitudinal Study

    K. Sgambat1, S. Clauss2, A. Moudgil1

    1Nephrology, Children's National Hospital, Washington DC, DC, 2Cardiology, Children's National Hospital, Washington DC, DC

    *Purpose: Kidney transplant recipients are at increased risk for cardiovascular disease but systolic function is often preserved and may not reveal cardiac dysfunction until it…
  • 2022 American Transplant Congress

    Renal Failure is Reversible in the Majority of Patients Transplanted for Alcohol-Associated Hepatitis: A Review of the UNOS Database

    Y. Bekki, G. Im, T. Schiano, S. Florman

    Icahn School of Medicine at Mount Sinai, RMTI, New York, NY

    *Purpose: The simultaneous liver-kidney (SLK) allocation policy in 2017 created Safety Net kidney allocation priority for liver transplant (LT) recipients with renal failure. Renal failure…
  • 2022 American Transplant Congress

    Post Heart Transplant Outcomes of Desensitized Durable Mechanical Circulatory Support Patients

    J. Youn1, D. Kim2, J. Choi2, K. Kim1, I. Kim3, E. Kransdorf4, D. Chang4, M. Kittleson4, J. Patel4, R. Cole4, J. Moriguchi4, D. Ramzy5, F. Esmailian5, J. A. Kobashigawa4

    1Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea, Republic of, 2Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, 3Keimyung University Dongsan Hospital, Daegu, Korea, Republic of, 4Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 5Department of Cardiothoracic Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: Desensitization therapy (DST) is considered to increase the chances of a negative crossmatch, to expand the number of suitable donors, and to improve post-transplant…
  • 2022 American Transplant Congress

    COVID-19 in Solid Organ Transplant: A Global Perspective

    .. C19TxR Consortium

    ESOT, NHSBT, UNOS, CareDx, South San Francisco, CA

    *Purpose: Transplantation has been disrupted dramatically by COVID-19 due to reallocation of healthcare resources and concerns from early reports of increased mortality rates (20-30%) in…
  • 2022 American Transplant Congress

    Pancreatic Islets Engineered with Thrombomodulin Show Enhanced Engraftment in an Intraportal Transplantation Model by Mitigating Instant Blood-Mediated Inflammatory Reactions

    A. Turan1, L. Zhang2, M. Tarique2, V. Ulker2, E. Yolcu3, H. Shirwan3

    1Molecular Microbiology and Immunology, University of Missouri at Columbia, Columbia, MO, 2Department of Child Health, University of Missouri at Columbia, Columbia, MO, 3Child Health and Molecular Microbiology and Immunology, University of Missouri at Columbia, Columbia, MO

    *Purpose: IBMIR is a major culprit of early islet loss post-transplant. Thrombomodulin (TM) is an anti-coagulant and cofactor of activated Protein C (APC) that perpetuates…
  • 2022 American Transplant Congress

    Role of Mitochondrial Transplantation in Enhancing Liver Regeneration Following Partial Hepatectomy

    G. Lamanilao1, C. Watkins1, C. Kuscu1, C. Kuscu1, J. Eason2, A. Bajwa1

    1Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, 2University of Tennessee/Methodist Transplant Institute, Memphis, TN

    *Purpose: Therapeutic strategies that accelerate the rate of liver regeneration following partial hepatectomy (PH) should be developed to reduce occurrences of small for size syndrome…
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