Am J Transplant, Volume 22, Suppl 3 Archives - Page 5 of 190 - ATC Abstracts

2022 American Transplant Congress
Impact of HMGB-1 SNPs on Comorbidities and Postoperative Complications in Liver Transplant Recipients
N. Tsukiyama¹, Y. Tanaka¹, Y. Imaoka¹, A. Seidakhmetov¹, R. Nakano¹, N. Tanimine¹, D. Marlen¹, M. Ohira², H. Tahara¹, K. Ide¹, H. Ohdan¹
¹Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan, ²Hiroshima University, Hiroshima, Japan
*Purpose: High-mobility group box 1 (HMGB-1) is an inflammatory mediator which becomes an uncontrollable lethal factor when released in excess from the nucleus or the…
2022 American Transplant Congress
The Effect of Tacrolimus and Mycophenolic Acid on Torque Teno Virus Loads in Kidney Transplant Recipients
A. van Rijn, S. Meziyerh, D. van der Helm, T. van Gelder, A. Kroes, J. de Fijter, D. Moes, J. Rotmans, A. de Vries, M. Feltkamp
Leiden University Medical Center, Leiden, Netherlands
*Purpose: Measuring immune function in kidney transplant recipients (KTRs) remains challenging given the precarious balance between over- and underimmunosuppression. This is primarily due to high…
2022 American Transplant Congress
Plasma Donor-Derived Cell-Free DNA Longitudinal Kinetics After Kidney Transplantation in Children
R. Dandamudi¹, S. Federman², R. Woodward², S. Dholakia², L. Walther¹, V. Dharnidharka¹
¹Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, ²CareDx, Brisbane, CA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) are DNA fragments released continuously into circulation from injured donor allograft cells. In adult studies, the levels drop to a…
2022 American Transplant Congress
Single-cell Transcriptomic Analysis Of Peripheral Blood Reveals The Disparate Subsets Of Innate Immune Cells In Kidney Transplant Recipient With BK Virus Infection
H. BAE¹, J. Ryu², J. Jang¹, J. Lee¹, G. Ko¹, H. PARK¹, E. Oh³
¹Department of Biomedical Science, Graduate School, College of medicine, The Catholic university of Korea, Seoul, Seoul, Korea, Republic of, ²Department of Laboratory Medicine, College of Medicine, Seoul St. Mary’s hospital, the Catholic University of Korea, seoul, Korea, Republic of, ³Catholic University Department of Laboratory Medicine, Seoul 137-040, Korea, Republic of
*Purpose: BK virus (BKV) infection is a common problem in kidney transplant recipients receiving immunosuppressive therapy, resulting in a serious complications including BKV-associated nephropathy and…
2022 American Transplant Congress
A Randomised Trial Of Normothermic Machine Perfusion Versus Static Cold Storage In Donation After Circulatory Death Renal Transplantation
S. Hosgood¹, C. Callaghan², C. Wilson³, G. Oniscu⁴, B. Phillips⁵, L. Bates³, L. Smith⁶, M. L. Nicholson⁷
¹Surgery, University of Cambridge, Cambridge, United Kingdom, ²Transplant, Guys & St Thomas's, London, United Kingdom, ³Transplant, Freeman Hospital, Newcastle, United Kingdom, ⁴Edinburgh Royal Infirmary, Edinburgh, United Kingdom, ⁵Transplant, Guy's & St Thomas's, London, United Kingdom, ⁶NHSBT, NHSBT, Bristol, United Kingdom, ⁷University of Cambridge, Cambridge, United Kingdom
*Purpose: Kidneys from donation after circulatory death (DCD) donors are more susceptible to cold storage injury and have a high risk of delayed graft function…
2022 American Transplant Congress
Transplant Centers That Assess Frailty as Part of Clinical Practice Have Better Outcomes
X. Chen¹, Y. Liu¹, V. Thompson¹, N. M. Chu¹, E. A. King¹, J. D. Walston², J. A. Kobashigawa³, D. M. Dadhania⁴, D. L. Segev¹, M. A. McAdams-DeMarco¹
¹Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, ²Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, ³Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, ⁴Division of Nephrology and Hypertension, Weill Cornell Medicine, New York, NY
*Purpose: Frailty predicts adverse post-kidney transplant (KT) outcomes, yet impacts of frailty assessments on center-level outcomes remain unclear. We tested whether transplant centers assessing frailty…
2022 American Transplant Congress
A Randomized, Controlled, Double-blind Trial Of Inulin To Boost Response To A Third Covid-19 Vaccine Dose In Kidney Transplant Recipients.
J. Singer¹, M. Tunbridge², T. Salehi³, G. Perkins⁴, B. Grubnor-Bauk⁵, B. Sim³, T. Ying⁶, P. T. Coates³, S. J. Chadban¹
¹Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia, ²Renal Medicine, Royal Adelaide Hospital, Adelaide, Australia, ³Royal Adelaide Hospital, Adelaide, Australia, ⁴School of Biological Sciences, University of Adelaide, Adelaide, Australia, ⁵Adelaide University, Adelaide, Australia, ⁶Royal Prince Alfred Hospital, Sydney, Australia
*Purpose: Kidney transplant recipients (KTR) commonly exhibit inadequate responses to 2-dose COVID-19 vaccination schedules and remain at increased risk of severe COVID-19. Gut dysbiosis is…
2022 American Transplant Congress
Technology Enabled And Molecular Monitoring Of The Allograft And Transplant Recipient Study
N. Sulejmani¹, D. Axelrod², S. Dholakia¹, S. Shah³
¹CareDx, South San Francisco, CA, ²University of Iowa, Iowa City, IA, ³University of Cincinnati, Cincinnati, OH
*Purpose: With the widespread availability of smart mobile devices, mobile health (mHealth) provides the opportunity to reach wide array of patients. Readmission rates as high…
2022 American Transplant Congress
A Multicenter Randomized Controlled Trial To Compare The Efficacy Of Ex-vivo Machine Perfusion With Static Cold Storage In Human Liver Transplantation: The University Of Maryland Experience
J. Avruch¹, N. Goussous², S. Malik¹, M. Pinedo¹, R. Meier¹, C. Bhati¹, D. Maluf¹, R. Barth³, J. Alvarez-Casas¹
¹Transplant Surgery, University of Maryland School of Medicine, Baltimore, MD, ²Transplant Surgery, University of California Davis Health, Davis, CA, ³University of Chicago, Chicago, IL
*Purpose: There is accumulating clinical evidence of the benefit of normothermic ex-vivo machine perfusion (NMP) compared with traditional static cold storage of liver allografts prior…
2022 American Transplant Congress
The Development of a Scientific Registry of Transplant Recipients Data Query Tool: A Human-Centered Design Process
C. Schaffhausen¹, A. Hart², C. S. Zinner³, A. K. Israni², J. Snyder¹
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²Hennepin Healthcare (HHS) / University of Minnesota (UMN), Minneapolis, MN, ³Accenture Federal Services, Washington, DC
*Purpose: The Scientific Registry of Transplant Recipients (SRTR) provides national transplant data in various forms, including the OPTN/SRTR Annual Data Report (ADR). The ADR includes…

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