ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Final Flow and Resistance with Cold Pulsatile Perfusion Preservation Are Independent Risk Factors for Dialysis in the First Week Post-Transplant, Analysis of SRTR Data

    D. S. Keith, E. Lessmann

    Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine if final flow or resistance on cold pulsatile perfusion preservation (CPPP) have independent predictive value for dialysis in the first week post-transplant.*Methods:…
  • 2022 American Transplant Congress

    VCA Waiting List and Transplant Trends and Challenges in the US

    J. Wainright1, W. Cherikh1, S. Booker1, D. Klassen2

    1Research, UNOS, Richmond, VA, 2Office of the CMO, UNOS, Richmond, VA

    *Purpose: VCA transplantation has grown and changed, encountering challenges such as scarce funding sources and the COVID-19 pandemic.*Methods: The OPTN cohort includes 105 candidates listed…
  • 2022 American Transplant Congress

    Crosstalk Between micro-RNAs, mRNAs, and Long Non-Coding RNAs in Human Hepatic Ischemia Reperfusion Injury

    C. Kuscu1, S. Naik1, C. Eymard2, A. Bajwa1, D. Maluf3, V. Mas3, J. Eason4, C. Kuscu1

    1Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, 2James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, 3Surgery, University of Maryland, Baltimore, MD, 4University of Tennessee/Methodist Transplant Institute, Memphis, TN

    *Purpose: Present study utilizes multiple omics tools and clinical samples with a system biology approach characterizing mRNAs, long non-coding RNAs (lncRNAs) and small non-coding RNAs…
  • 2022 American Transplant Congress

    Donor App Increases Awareness and Overall Rates of Living Kidney Donation

    T. Shamaa1, I. Bajjoka1, H. Kandalaft1, R. Prashar2, M. Callaghan1, C. Crombez1, S. J. Serra1, M. Abouljoud1, J. Denny1

    1Transplant and Hepatobiliary Surgery, Henry Ford Transplant Institute, Detroit, MI, 2Transplant Nephrology, Henry Ford Transplant Institute, Detroit, MI

    *Purpose: The rate of living donor kidney transplants (LDKTs) performed has declined overall regardless of race. Studies show that web-based tools increase access to living…
  • 2022 American Transplant Congress

    Moving Beyond the Waitlist in Measurement of Access in Kidney Transplantation

    L. C. McMichael, D. T. Chang, M. Kadatz, J. Gill

    University of British Columbia, Vancouver, BC, Canada

    *Purpose: Studies limited to waitlist candidates have suggested better access to kidney transplantation and fewer disparities in acesss since the new kidney allocation system (KAS)…
  • 2022 American Transplant Congress

    Characterization of ICU Delirium Among Liver Transplant Recipients

    J. M. Ruck, K. Neufeld, E. Oh, J. C. Lai, E. King

    Johns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: Delirium has been shown to impact the hospital courses of older adults. Liver transplant (LT) recipients are a population that has previously been identified…
  • 2022 American Transplant Congress

    Artificial Intelligence Based Dosing of Tacrolimus in Liver Transplantation: Prospective, Randomized Phase 2 Trial

    A. Zarrinpar1, C. Ho2, C. Warren1, J. Khong2, M. Lee2, S. Duarte1, K. Andreoni1, M. Johnson1, N. Battula3, D. McKimmy1, T. Beduschi1

    1Surgery, University of Florida, Gainesville, FL, 2Mechanical and Aerospace Engineering, University of California, Los Angeles, CA, 3Surgery, University of Oklahoma, Oklahoma City, OK

    *Purpose: Inter- and intra-individual variability in calcineurin dose requirements necessitates empirical clinician-titrated dosing that frequently results in deviation from target ranges, particularly during the critical…
  • 2022 American Transplant Congress

    Evaluation of Hepatitis C Positive Donor to Hepatitis C Negative Recipient Kidney Transplant in a Highly Sensitized Patient Population

    A. T. Iaria, M. Martin, A. Hietpas, I. Tang, S. Koppe, I. Tzvetanov, E. Benedetti, C. Muran

    University of Illinois at Chicago, Chicago, IL

    *Purpose: This study assessed outcomes of hepatitis C virus (HCV) donor positive to recipient negative (D+/R-) kidney transplants (KT) in high immunologic risk patients. Literature…
  • 2022 American Transplant Congress

    Iguratimod Alleviates Endothelial to Mesenchymal Transition by Inducing AMBRA1/PARKIN-Dependent Mitophagy and Inhibiting NLRP3 Activation During Renal Allograft Interstitial Fibrosis

    Z. Gui1, W. Zijie2, M. Zheng3, R. Tan3, M. Gu4

    1Department of Urology, The Second Affiliated Hospital with Nanjing Medical University, Nanjing, China, 2Jiangsu Province Hospital, Nanjing, China, 3Department of Urology, the First Affiliated Hospital with Nanjing Medical University, Nanjing, China, 4Department of Urology, the Second Affiliated Hospital with Nanjing Medical University, Nanjing, China

    *Purpose: Chronic renal graft dysfunction (CAD) is caused by multiple factors, including glomerular sclerosis, inflammation, interstitial fibrosis and tubular atrophy (IF/TA). However, the most prominent…
  • 2022 American Transplant Congress

    Alloreactive Human Regulatory T Cell-Derived Extracellular Vesicles Exhibit Adenosinergic Mediated Suppression and Potential for Infectious Tolerance

    B. Schreiber, S. Tripathi, A. Chandraker

    Brigham and Women's Hospital, Boston, MA

    *Purpose: Regulatory T cells (Tregs) suppress the immune response through both contact dependent and independent mechanisms. Extracellular vesicles (EVs) are emerging as novel contact independent…
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