Am J Transplant, Volume 22, Suppl 3 Archives - Page 184 of 190 - ATC Abstracts

2022 American Transplant Congress
Combined CyTOF and Elispot Investigation of CMV Response Over the First Year Post Kidney Transplantation
T. Jouve¹, L. Donadeu Casassas², S. Hartzell³, E. Crespo², M. Meneghini², A. Torija², P. Cravedi⁴, O. Bestard²
¹Nephrology, Vall d’Hebron Institut de Recerca (VHIR), Grenoble, Spain, ²Nephrology, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain, ³Mount Sinai Hospital, New York, NY, ⁴Mount Sinai, New York, NY
*Purpose: CMV remains a threat for kidney transplant recipients (KTR). Deciphering the impact of CMV on the immune system of KTR has helped improving CMV…
2022 American Transplant Congress
Comparing Disparities in Access to First and Re-Kidney Transplantation Among Hispanic and Black Adults in the United States
S. Sandal¹, J. Ahn², V. Thompson³, T. Purnell⁴, M. Cantarovich⁵, D. Segev³, M. McAdams DeMarco³
¹McGill University, Montreal, QC, Canada, ²SOM, Johns Hopkins University, Baltimore, MD, ³Johns Hopkins University, Baltimore, MD, ⁴Johns Hopkins School of Medicine, Baltimore, MD, ⁵McGill University Health Ctr, Montreal, QC, Canada
*Purpose: There are significant racial/ethnic disparities in access to solid organ transplantation; lack of education and familiarity with the transplant process are postulated contributors. Among…
2022 American Transplant Congress
Autencoder, a Novel Computational Tool to Score T Cell Clones Demonstrates Biopsy T Cell Clones Are Not Represented in the Peripheral Blood
N. Borcherding, A. Leckie-Harre, H. Wu, B. D. Humphreys, A. F. Malone
Washington University, St Louis, MO
*Purpose: Antibody-mediated rejection (AMR) remains one of the major causes of allograft failure and our understanding of this disease process is poor. The generation and…
2022 American Transplant Congress
130 Totally Robotic Donor Hepatectomy: Reproducibility Of A Standardized Technique Across 2 Specialized Centers
Y. Cheah¹, H. Yang², C. J. Simon¹, J. Kim³, M. Akoad³, G. Choi²
¹Roger L Jenkins Transplant Institute, Lahey Hospital & Medical Center, Burlington, MA, ²Division of HPB Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of, ³Lahey Hospital & Medical Center, Burlington, MA
*Purpose: Robotic surgery is emerging as a feasible though complex technique to enable minimally-invasive donor hepatectomy.*Methods: First multicenter prospective study on 130 consecutive totally robotic…
2022 American Transplant Congress
Disruption of B Cell Population is Associated with Increased Infections in Pediatric Transplant Recipients
B. Geng, L. Loop, C. Anterasian, D. Mortazavi, J. Kitsen, C. Collins, K. Newton, E. Ingulli
Pediatrics, UCSD Rady Children's, San Diego, CA
*Purpose: Solid-organ transplant recipients are placed on long-term immunosuppression, preventing graft rejection but increasing the risk of infection. Pediatric transplant recipients are at increased risk…
2022 American Transplant Congress
Kidney Transplant Alone Recipients with Advanced Liver Disease Have Similar Outcomes to Those without Advanced Liver Disease
R. R. Nathani, S. M. Rutledge, C. Villarroel, R. Shapiro, G. Y. Im
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: The prevalence of concomitant liver disease (CLD) in patients with ESRD is reported to be 7-40%. Safety of kidney transplant alone (KTA) in those…
2022 American Transplant Congress
Cost-Effectiveness of Transplanting Hepatitis C Donor Hearts Into Hepatitis C Uninfected Recipients
A. R. Gandhi¹, A. E. Woolley², L. R. Baden², M. M. Givertz², M. L. Jones¹, J. Kim³, H. R. Mallidi², M. R. Mehra², A. M. Neilan¹
¹Massachusetts General Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, MA, ³Harvard T.H. Chan School of Public Health, Boston, MA
*Purpose: To examine the clinical impact and cost-effectiveness of hepatitis C viremic (HCV+) heart organ donation in the United States.*Methods: We used a microsimulation model…
2022 American Transplant Congress
Poor Tolerability of CFTR Modulator Therapy in Lung Transplant Recipients
C. Doligalski, C. McKinzie, A. Yang, R. Coakley
UNC Health, Chapel Hill, NC
*Purpose: Elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) is a highly effective therapy for cystic fibrosis (CF) with potential benefits in lung transplant recipients (LTRs) for extrapulmonary CF manifestations, however…
2022 American Transplant Congress
Identification of a Unique and Mechanistic Urinary Cell mRNA Signature in Tolerant Kidney Transplant Recipients Conditioned with FCR001 Facilitating Cells
J. Lee¹, J. R. Leventhal², C. Li³, R. Ding¹, S. Ildstad⁴, M. Suthanthiran⁵
¹Weill Cornell Medicine, New York, NY, ²Surgery, Northwestern Medicine, Chicago, IL, ³Medicine, WCMC, New York, NY, ⁴Univ Louisville / Talaris, Louisville, KY, ⁵Weill Cornell Med, New York, NY
*Purpose: Urinary cell mRNA profiling is a powerful tool to interrogate kidney allograft status and can diagnose and anticipate acute rejection in kidney allograft recipients.…
2022 American Transplant Congress
HCK is a Key Regulator for Macrophage Polarization in Kidney Fibrosis
C. Wei, M. Chen, Z. Sun, Z. Yi, C. He, W. Zhang
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Interstitial fibrosis and tubular atrophy (IF/TA) is common histological abnormality in biopsy of kidney transplants. Our previous study from a prospective human kidney transplant…