2022 American Transplant Congress
Integrated Alcohol Use Disorder Clinic as a Strategy to Reduce Alcohol Relapse After Early Liver Transplantation in Patients with Alcohol Related Liver Disease
*Purpose: In recent years, for patients with Alcohol related Liver Disease (ALD), there has been a trend towards early Liver Transplantation (LT) rather than waiting…2022 American Transplant Congress
Critical Care of the Brain-Dead Recipient of a Pig-to-Human Renal Transplant
1NYU Langone Transplant Institute, New York, NY, 2NYU Langone Health, New York, NY
*Purpose: The care of a brain dead (BD) patient undergoing xenotransplantation in a non-clinical environment poses unique challenges. Selection of an appropriate decedent, stabilization of…2022 American Transplant Congress
Use of Ancestral Genetic SNP Phenotyping to Define Genotypic Ethnicity in Solid Organ Transplant Patients
Surgery, Baylor College of Medicine, Houston, TX
*Purpose: Transplantation research has mainly categorized ethnicity into four main groups African American, Caucasian, Hispanic, and Asian Pacific Islander. Our world has increased in admixure…2022 American Transplant Congress
Detection of CMV Mediated Sub-Clinical Rejection by Urine Biomarkers
1Nephrosant Inc, San Francisco, CA, 2UCLA, Los Angeles, CA, 3UCSF, San Francisco, CA
*Purpose: Research on early detection of Cytomegalovirus (CMV) mediated sub-clinical rejection (sAR) is in its nascence. This study explores the efficacy of urine-based biomarkers for…2022 American Transplant Congress
Detection of Alloreactive CD8+ T Cell Responses and the Immunopeptidome That Elicits Their Activation
*Purpose: T cell-mediated rejection results in graft dysfunction and contributes to premature failure. Due to the complexity of the TCR:pMHC interaction, prediction of alloreactive T…2022 American Transplant Congress
Single Nuclei RNA-Sequencing Identifies Distinct Cell Profile in Kidney Allografts with Recurrent Focal Segmental Glomerular Sclerosis (FSGS)
1NWU, Chicago, IL, 2University of Maryland, Baltimore, MD, 3UTHSC, Memphis, TN
*Purpose: Strong evidence suggests that primary FSGS is due to a plasma factor that results in general podocyte dysfunction and risk of recurrence after kidney…2022 American Transplant Congress
Association of Psychosocial Clearance and Race in the Kidney Transplant Evaluation Process
*Purpose: The psychosocial evaluation of transplant candidates is a comprehensive assessment of the (Fig 1). Psychosocial risk factors can be the only basis for not…2022 American Transplant Congress
Evaluation of Crushed Posaconazole Delayed Release Tablets in Lung Transplant Recipients
*Purpose: We hypothesized that crushed posaconazole delayed release (POSA DR) tablets can reach therapeutic levels in lung transplant recipients who are at risk for invasive…2022 American Transplant Congress
A Multi-Center Study Assessing the Association of Frailty with Infection in Kidney Transplant Recipients
*Purpose: Frailty is a multi-dimensional characterization of decreased reserve and diminished response to stressors in older adults. Frailty at the time of transplant has been…2022 American Transplant Congress
HLA-Specific IgD/CD27 Double Negative B Cell Frequency Assessed by a Novel Multiplex Bead-Based Assay Predicts Rejection in Kidney Transplant Recipients
*Purpose: Recipients with sensitization to HLA defined by a high percentage of Panel Reactive Antibodies (PRA) or Donor-specific anti-HLA antibodies (DSA) are at higher immunologic…
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