Am J Transplant, Volume 22, Suppl 3 Archives - Page 18 of 190 - ATC Abstracts

2022 American Transplant Congress
High-Level Pre-Transplant C-Peptide Among T2d Recipients of Simultaneous Pancreas and Kidney Transplants is Associated with Reduced Pancreatic Graft Function
S. Parajuli, D. Mandelbrot, D. Aufhauser, D. Kaufman, J. Odorico
University of Wisconsin, Madison, WI
*Purpose: Among selected patients with end-stage renal disease (ESRD) and type 2 diabetes (T2DM), simultaneous pancreas and kidney (SPK) transplants can be an effective option,…
2022 American Transplant Congress
Incidence and Risk Factors Associated with the Development of Hypoglycemia After Combined Pancreas-Kidney Transplantation
S. Kapoor¹, S. Jain², S. Stefan³, Y. Azzi³, M. Ajaimy³, P. Loarte-Campos³, C. Pynadath³, H. C. Yaffe³, M. Le³, J. Rocca³, S. Greenstein³, M. Kinkhabwala³, J. Graham³, E. Akalin⁴, L. Liriano-Ward³
¹Montefiore Medical Center, New York, NY, ²Montefiore Medical Center, Scarsdale, NY, ³Montefiore Medical Center, Bronx, NY, ⁴Albert Einstein College of Medicine, Montefiore Medical Ctr, Bronx, NY
*Purpose: To review the incidence of hypoglycemia after pancreas transplantation in recipients with type 1 and 2 diabetes mellitus and the risk factors associated with…
2022 American Transplant Congress
Incidence and Outcomes of CMV Infection in Pancreas Transplant with Thymoglobulin Induction: A Single Center Experience
W. Abusalah, A. Yadav
Thomas Jefferson University Hospital, Philadelphia, PA
*Purpose: CMV infection is a major infectious complication in pancreas transplant recipients (PTR). Incidence of CMV viremia in PTR with thymoglobulin induction and it's effect…
2022 American Transplant Congress
Lung Allograft-Resident Eosinophils Maintain Long-Term Graft Integrity by Restraining Humoral Alloimmunity
Z. Mei¹, Y. Guo¹, D. Li¹, M. Khalil¹, A. Banerjee¹, A. Gelman², D. Kreisel², A. Krupnick³
¹Department of Surgery, University of Maryland, Baltimore, Baltimore, MD, ²Washington University in St. Louis, St. Louis, MO, ³Department of Surgery, University of Maryland, Baltimore, baltimore, MD
*Purpose: The finding that eosinophils facilitate immunosuppression-mediated acceptance of murine lung allograft by downregulating alloreactive CD8+ T cells has been recently described by our group.…
2022 American Transplant Congress
Discrepancy Rates Between Histology (HIST) and Molecular Diagnosis (MDX) of T-cell Mediated Rejection (TCMR) Depend on Choice of Bioinformatics Pipeline
M. Ellison, D. Spagnolo, P. Randhawa
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: HIST based treatment of TCMR has played a key role in the reduction of its incidence to historic lows of ~10%. MDX methods developed…
2022 American Transplant Congress
Outcomes of Living Liver Donors Are Worse Than Those of Matched Healthy Controls: Nationwide Cohort Study
J. Kim¹, J. Choi², J. Kim³, H. Kim⁴, J. Joh¹
¹Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, ²Department of Surgery, Myongji Hospital, Goyang, Korea, Republic of, ³Department of Urology, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea, Republic of, ⁴Department of Preventive Medicine, Korea University, Seoul, Korea, Republic of
*Purpose: Donor death is the most serious complication of living liver donation, but is reported rarely. We investigated the actual mortality of living liver donors…
2022 American Transplant Congress
Effect of Mycophenolate Mofetil Dosing on Antibody Response to SARS-CoV-2 Vaccination in Heart and Lung Transplant Recipients
J. Mitchell¹, T. P. Chiang¹, J. Alejo¹, A. Chang¹, A. Abedon¹, R. Avery¹, A. Tobian¹, A. Massie¹, M. Levan¹, D. Warren¹, J. Garonzik-Wang², D. Segev¹, W. Werbel¹
¹Johns Hopkins University, Baltimore, MD, ²University of Wisconsin-Madison, Madison, WI
*Purpose: Mycophenolate mofetil (MMF) use is associated with decreased antibody response to the SARS-CoV-2 mRNA vaccine series in heart and lung transplant recipients (HLTRs). Higher…
2022 American Transplant Congress
Early Tacrolimus Exposure is Associated with BK-Viremia in Kidney Transplant Recipients
S. Meziyerh, A. L. van Rijn, D. van der Helm, P. J. van der Boog, T. van Gelder, A. C. Kroes, J. W. de Fijter, D. J. Moes, J. I. Rotmans, M. C. Feltkamp, A. P. de Vries
LUMC, Leiden, Netherlands
*Purpose: There is scant evidence to what extent maintenance immunosuppression is quantitatively associated with BK viremia. We investigated the association between tacrolimus (tac) whole blood…
2022 American Transplant Congress
Ikaros-SIRT1 Signaling Axis Regulates Macrophage Pyroptosis and Ischemia-Reperfusion Injury (IRI) in Mouse and Human Liver Transplantation
K. Kadono¹, H. Hirao¹, H. Kojima¹, K. J. Dery¹, X. Li², J. Kupiec-Weglinski¹
¹UCLA Medical Center, Los Angeles, CA, ²NIEHS, Durham, NC
*Purpose: Although Ikaros is a well-established regulator of lymphopoiesis, its role in myeloid cells and organ IRI remains unclear. We recently reported that the SIRT1-mediated…
2022 American Transplant Congress
Donor-Specific T Cell Senescence In Operationally Tolerant Liver Transplant Recipients
K. Deng¹, N. Tanimine², C. Breeden³, B. Burrell³, G. Gaile³, K. Lee¹, R. Matheson¹, F. Qiang¹, C. Rickert¹, C. LeGuern¹, J. Markmann¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Department of Gastroenterological and Transplantation Surgery, Hiroshima University, Hiroshima, Japan, ³Immune Tolerance Network, Bethesda, MD
*Purpose: Recent evidence indicates a correlation in liver transplant recipients between successful operational tolerance (OT) post immunosuppression withdrawal (ISW) with both recipient age and time…