Am J Transplant, Volume 22, Suppl 3 Archives - Page 178 of 190 - ATC Abstracts

2022 American Transplant Congress
Monitoring of Kidney Allograft Rejection Using Patient-Centric State-of-the-Art Tools – An Approach to Early Diagnosis and Intervention
A. Rizvi¹, A. Gamilla-Crudo², S. A. Hussain³, M. Kueht⁴, J. Fair⁴, M. Mujtaba²
¹Internal Medicine, Nephrology, University of Texas Medical Branch, Galveston, TX, ²University of Texas Medical Branch, Galveston, TX, ³Nephrology, University of Texas Medical Branch, Houston, TX, ⁴Surgery, University of Texas Medical Branch, Galveston, TX
*Purpose: The early detection and timely management of kidney allograft rejection using traditional markers including serum creatinine (SCr) has been inadequate due to lagging response.…
2022 American Transplant Congress
Preclinical Evaluation of Functional Survival of Stem Cell Derived Islets Microencapsulated in Alginate with CXCL12 in Non-Human Primates without Immunosuppression
M. C. Poznansky
Vaccine and Immunotherapy Center, Massachusetts General Hospital, Charlestwon, MA
*Purpose: Human stem cell-derived islet-like cells (SC-islets) represent a sustainable source for beta-cell replacement to achieve a functional cure for type 1 diabetes. We previously…
2022 American Transplant Congress
Pure Laparoscopic versus Open Right Hepatectomy in Living Liver Donors (Graft Weight Discrepancy)
J. Seo¹, S. Hong¹, S. Lee², S. Suh², S. Hong¹, E. Han¹, Y. Choi², N. Yi², K. Lee³, K. Suh¹
¹Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of, ²Seoul National University College of Medicine, Seoul, Korea, Republic of, ³Seoul National University, Seoul, Korea, Republic of
*Purpose: The studies of volumetric evaluation in pure laparoscopic donor hepatectomy (PLDH) are relatively less known than that of conventional donor hepatectomy. The aim of…
2022 American Transplant Congress
How Does Anti-CD38 Antibody Treatment (Daratumumab) Impact Immunological Assessment in Solid Organ Transplantation?
S. Ho¹, K. Putnam², C. Peiter², W. Herczyk², J. Gerlach³, E. Campagnaro⁴, Y. Lu⁴, K. Woodside⁴, M. Cusick⁴
¹Gift of Hope Organ & Tissue Donor Network, Itasca, IL, ²Gift of Life Michigan, Ann Arbor, MI, ³Michigan State University, East Lansing, MI, ⁴University of Michigan Medicine, Ann Arbor, MI
*Purpose: We report the first case of Dara interference of routine pre-transplant (Tx) crossmatch (XM) repeatedly causing aberrant false positives which inadvertently delayed Tx for…
2022 American Transplant Congress
Effect of Sars-CoV-2 Delta Variant on Post-Vaccination COVID-19 Infection in Solid Organ Transplant Recipients
E. Tuttle¹, J. Moon², T. J. Grazia³, T. Sam⁴, S. Mathai³
¹Pulmonary and Critical Care Department, Baylor University Medical Center, Dallas, TX, ²Department of Internal Medicine, Baylor University Medical Center, Dallas, TX, ³Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, TX, ⁴Department of Pharmacy, Baylor University Medical Center, Dallas, TX
*Purpose: In July 2021, the SARS-CoV-2 Delta variant emerged as the dominant strain in the North Texas area. We reviewed COVID-19 infections post-vaccination in Solid Organ…
2022 American Transplant Congress
The Effectiveness of Healthcare-Associated Infections Prevention Measures in the Incidence of Infections and In-Hospital Mortality After Liver Transplantation: A Quasi-Experimental Single-Center Study
C. Bittante¹, L. R. Requião-Moura², F. Menezes¹, S. Morgado¹, L. Correa³, L. Camargo²
¹Hospital Israelita Albert Einstein, São Paulo, Brazil, ²Universidade Federal de São Paulo, São Paulo, Brazil, ³Universidade Federal de São Paulo, Sao Paulo, Brazil
*Purpose: To evaluate the effectiveness of multifaceted control interventions (bundles) aimed at preventing multiple healthcare-associated infections (HAI) in liver transplant recipients.*Methods: This quasi-experimental study enrolled…
2022 American Transplant Congress
Impact of End-of-Chain Kidney Allocation on Access to Kidney Transplantation of Minority Patients: Implications for Reducing Disparities
J. Wade¹, K. Rancourt², A. Anane², A. Landeen², J. U. Singh³, X. Ye³, J. Tremaglio³, Z. Ebcioglu³, R. Kent³, B. Emmanuel⁴, G. Morgan⁴, O. K. Serrano⁴, W. Dar⁴
¹Department of Surgery, Surgical Research Program, Hartford Hospital, Hartford, CT, ²Hartford Hospital Transplant & Comprehensive Liver Center, Hartford, CT, ³Department of Medicine, Hartford Hospital Transplant & Comprehensive Liver Center, Hartford, CT, ⁴Department of Surgery, Hartford Hospital Transplant & Comprehensive Liver Center, Hartford, CT
*Purpose: Disparities in access to kidney transplantation (KT) among non-White patients is well-known, especially as it relates to living donor kidney transplantation (LDKT). We investigated…
2022 American Transplant Congress
Randomized, Phase 4 Study Evaluating the Pharmacokinetics and Tolerability of the New Tacrolimus Tablet Formulation (Tacrobell Tab) in Kidney Transplant Recipients
A. Han¹, E. Cho¹, H. Y. Woo¹, C. Ara¹, H. Lee², Y. Kim³, Y. Park⁴, J. Oh⁴, S. Min¹, J. Ha¹
¹Department of Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of, ²Seoul National University Hospital, Seoul, Korea, Republic of, ³Department of Nephrology, Seoul National University College of Medicine, Seoul, Korea, Republic of, ⁴Department of Clnical Pharmacology, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: Previous twice-a-day tacrolimus formulations available were capsular and of limited dose formulations (0.5mg, 1mg). Recently a new tablet formulation of tacrolimus with more diverse…
2022 American Transplant Congress
The Promise Of Tolerance In Living Donor Kidney Transplant (LDKT): A Retrospective, Real-world Assessment Of The Safety And Efficacy Of LDKT With FCR001 Investigational Cell-therapy Compared With Standard Of Care (SOC)
N. Krieger¹, J. R. Leventhal², B. Ho³, M. Richards⁴, D. Schaumberg⁴, S. Ildstad⁵, D. Axelrod⁶
¹Talaris Therapeutics, Inc, Wellesley, MA, ²SURGERY, Northwestern Medicine, Chicago, IL, ³Comprehensive Transplant Ctr, Chicago, IL, ⁴Evidera, Bethesda, MD, ⁵Talaris Therapeutics, Inc., Louisville, KY, ⁶University of Iowa, Iowa City, IA
*Purpose: FCR001 (FCR) is a cell therapy derived from mobilized donor PBMCs including hematopoietic progenitor cells, facilitating cells, and αβ T cells, intended to establish…
2022 American Transplant Congress
Analytical Evaluation and Comparison to STR of an Accurate and Sensitive Microchimerism Monitoring Tool for Liver Transplant Recipients
A. S. Kothari¹, C. Egidio¹, J. Miles², N. Gulbahce¹, S. Dholakia³, M. Grskovic⁴
¹Clinical Development, CareDx, South San Francisco, CA, ²Medical Affairs, CareDx, Brooklyn, NY, ³Medical Affairs, CareDx, South San Francisco, CA, ⁴CareDx, Brisbane, CA
*Purpose: Peripheral blood chimerism is associated with clinically relevant events post liver transplantation (LT). Accurate quantification of donor chimerism in LT recipients with ultra-sensitive chimerism…