Am J Transplant, Volume 22, Suppl 3 Archives - Page 178 of 190 - ATC Abstracts

2022 American Transplant Congress
Early Clinical Experience With Alvr109, A Partially Hla-matched Sars-cov-2 Specific T-cell Therapy, In Immunocompromised Patients With Covid-19
G. Haidar¹, J. Jacobs², K. Hughes², K. McCormick², A. Naqvi², M. Agha², T. Bogdanovich², B. Johnson², J. Kozar², E. Lendermon², C. Marino², A. Raptis², F. Silveira², W. Marshall³, M. Miller³, E. Atillasoy³, J. Mellors²
¹University of Pittsburgh, Pittsburgh, PA, ²UPitt, Pittsburgh, PA, ³Allovir, Waltham, MA
*Purpose: Therapies for COVID-19 in immunocompromised (IC) patients (pts), including transplant (tx) pts, are limited. We describe our experience with ALVR109, an allogeneic, partially HLA-matched…
2022 American Transplant Congress
In Vitro Fertilization Use Among Female Kidney Transplant Recipients
L. A. Coscia¹, J. M. Konel², M. Bowring³, S. Constantinescu⁴, M. J. Moritz⁵
¹Transplant Pregnancy Registry International, Philadelphia, PA, ²Wayne State University School of Medicine, Detroit, MI, ³Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, ⁵Surgery, Lehigh Valley Health Network, Allentown, PA
*Purpose: Infertility is common among female kidney transplant recipients (KTRs). In vitro fertilization (IVF) is a potential option. The purpose of this study was to…
2022 American Transplant Congress
Increased Regulatory T-cells in Tumor Microenvironment is Associated with Hepatocellular Carcinoma Differentiation in Patients Undergoing Liver Transplantation
G. Orozco¹, R. Gedaly², L. Turcios², F. Marti²
¹Surgery, University of Kentucky, Lexington, KY, ²UKHC, Lexington, KY
*Purpose: Tumor-infiltrating lymphocytes are an essential component of the tumor microenvironment. The balance between cytotoxic effector T cells and immunosuppressive regulatory T cells is critical…
2022 American Transplant Congress
Post-Kidney Transplant Valacyclovir versus Valganciclovir for CMV Prophylaxis: A Randomized Controlled Trial
P. S. Verghese¹, A. Matas², S. Chinnakotla², M. Evans³, H. Balfour Jr⁴
¹Univ of Minnesota Pediatric Nephrology, Minneapolis, MN, ²Surgery, University of Minnesota Medical School, Minneapolis, MN, ³Biostatistics, University of Minnesota, Minneapolis, MN, ⁴Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN
*Purpose: Valganciclovir (valG) is an effective CMV prophylactic agent post-kidney transplant (KTx) with significant side effects. Valacyclovir (valA) may be effective for CMV prophylaxis with…
2022 American Transplant Congress
Prevalence and Clinical Significance of Pancreatic Cystic Lesions in Immunosuppressed Patients with Solid Organ Transplantation
Y. Yu, H. Jo, Y. Choi, J. Lee, D. Kim
HBP surgery and liver transplantation, Korea University College of Medicine and School of Medicine, Seoul, Korea, Republic of
*Purpose: Solid organ transplant recipients have an increased risk of cancer due to immunosuppressive therapy. Pancreatic cystic lesions (PCLs) are increasingly being detected, some with…
2022 American Transplant Congress
First-in-Human Clinical-Grade Porcine Kidney Xenotransplant
J. E. Locke¹, B. Orandi¹, V. Kumar¹, J. Houp¹, D. Anderson¹, V. Hauptfeld¹, D. Martin², C. Killian¹, S. Macedon¹, N. Budd¹, K. Stegner¹, A. Dandro³, M. Kokkinaki³, K. Kuravi³, R. Reed⁴, H. Fatima¹, G. Baker¹, J. Perry¹, E. Bryant¹, M. Cheung¹, E. Erman¹, K. Kraebber¹, T. Gamblin¹, L. Guy¹, D. Ayares³, P. Porrett¹
¹University of Alabama at Birmingham, Birmingham, AL, ²Deakin University, Geelong, Australia, ³Revivicor, Incorporated, Blacksburg, VA, ⁴University of Alabama at Birmingham, Irondale, AL
*Purpose: Proof-of-concept xenotransplant work has been performed in pig to non-human primates (NHP), but it is unclear if outcomes can be recapitulated in humans. While…
2022 American Transplant Congress
The Post-operative Clinical Outcomes Of 59 Tanrp Cases In An International Cohort
J. Louca¹, N. Patel¹, S. Messer², J. Chindu², S. Large²
¹Cambridge University, Cambridge, United Kingdom, ²Royal Papworth Hospital, Cambridge, United Kingdom
*Purpose: Heart transplantation is an immensely effective service and is currently the only definitive treatment for heart failure. However, transplantation is limited by donor availability.…
2022 American Transplant Congress
Comparing Long-Term Outcomes of Steroid-Based versus Steroid-Avoidant Immunosuppression in Pediatric Kidney Transplant Recipients
N. Hayde¹, E. Blanchette², J. Zhang³, M. Chandran², M. Bock², S. Galbiati³, T. Blydt-Hansen⁴
¹Montefiore Medical Center, Bronx, NY, ²Children's Hospital Colorado, Aurora, CO, ³Emmes Corporation, Rockville, MD, ⁴University of British Columbia, Vancouver, BC, Canada
*Purpose: With increasing use of potent immunosuppressant (IS) medications, steroid-avoidant (SA) regimens are now commonly used for pediatric kidney transplant recipients (pKTs) to avoid potential…
2022 American Transplant Congress
Gender Affects the Association Between Serum Creatinine Levels and Clinical Response to Terlipressin in Patients with Hepatorenal Syndrome Type of Acute Kidney Injury
K. Jamil¹, R. Frederick², S. Pappas³
¹Hepatology, Mallinckrodt Pharmaceuticals, Clinton, NJ, ²Liver Disease/Hepatology & Transplant Hepatology, California Pacific Medical Center, San Francisco, CA, ³Orphan Therapeutics, LLC, Longboat Key, FL
*Purpose: Hepatorenal syndrome (HRS)-acute kidney injury (AKI) is a rare and serious complication of cirrhosis, with serum creatinine (SCr) used diagnostically. Women generally have less…
2022 American Transplant Congress
Creating a Workflow for the Electronic Medical Record Allows Living Donor Liver Transplantation Programs to Track Candidates and Identify Areas for Optimization
A. Liapakis¹, R. Batra¹, E. Cohen², D. Haakinson¹, M. Schilsky¹, K. Ventura², D. Mulligan¹
¹Yale University School of Medicine, New Haven, CT, ²Yale New Haven Hospital, New Haven, CT
*Purpose: To provide a pathway to increase living donor liver transplantation (LDLT) opportunities through creation of a simple workflow algorithm embedded within the EPIC electronic…