Am J Transplant, Volume 22, Suppl 3 Archives - Page 176 of 190 - ATC Abstracts

2022 American Transplant Congress
The High Acuity Index: A Posttransplant Prediction Score for High-MELD Patients
C. R. Christmann¹, A. Anand¹, G. Handing¹, A. Rana²
¹School of Medicine, Baylor College of Medicine, Houston, TX, ²Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: Patients with a very high Model for End-Stage Liver Disease (MELD) score are at significant short-term risk for death without liver transplantation. While many…
2022 American Transplant Congress
Favorable Outcomes in Older Diabetics Receiving a Simultaneous Kidney Pancreas Transplant Compared to Those Receiving a Living Donor Kidney Transplant
P. Budhiraja¹, H. Me¹, J. Ninan², S. Reddy², S. S. Misra¹, R. Heilman¹, H. Khamash¹, K. Reddy¹, C. Jadloweic¹, N. Katariya¹, H. Chakkera¹
¹Mayo Clinic, Phoenix, AZ, ²Mayo Clinic, Rochester, MN
*Purpose: To compare the long-term outcomes of older (50-65 yr) diabetic patients who received Simultaneous Kidney pancreas transplantation (SKP) vs. living donor (LD) kidney transplants.*Methods:…
2022 American Transplant Congress
Do Social Support Requirements Delay Time to Listing Decision in Liver Candidates?
M. Jesse¹, A. Peleman¹, M. Karrick¹, F. Nimri¹, N. Parikh², A. Segal¹, D. Moonka¹, M. Abouljoud¹, A. Yoshida¹
¹Henry Ford Health System, Detroit, MI, ²University of Michigan, Ann Arbor, MI
*Purpose: Social support requirements in the evaluation of transplant candidates have recently come under increased scrutiny. One criticism is that these requirements delay listing decisions.…
2022 American Transplant Congress
Pretransplant Recipient TNFR2⁺T Regulatory Cell Frequency Predicts Long-Term Outcomes After Kidney Transplantation
A. Kouyoumdjian, N. Saberi, S. Negi, J. Tchervenkov, S. Paraskevas
McGill University Health Centre, Montreal, QC, Canada
*Purpose: Pre-transplant indices capable of predicting long-term renal allograft function could improve graft allocation strategies. We previously associated pretransplant frequency of Tumor Necrosis Factor Receptor…
2022 American Transplant Congress
P2X7R Signaling Controls Exosome Release by Macrophages and Donor MHC Cross-Dressing After Skin Transplantation
H. H. Lancia¹, N. Carnel², A. G. Lellouch¹, C. Cetrulo¹, G. Benichou²
¹Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, ²Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA
*Purpose: Exosomes released by transplanted organs play an important role in the host's immune response leading to their rejection. Donor exosomes contribute to alloimmunity by…
2022 American Transplant Congress
Proteome Profiling of Recurrent Primary Focal Segmental Glomerulosclerosis (FSGS) Plasma Samples Reveals Potential Proteins Involved in Primary FSGS
L. Gallon¹, N. Ahsan², V. Mas³, J. Leventhal¹, L. Fornelli²
¹Northwestern Univ NMFF, Chicago, IL, ²Mass Spectrometry, Proteomics and Metabolomics Core Facility, Department of Chemistry and Biochemistry, The University of Oklahoma, Oklahoma, OK, ³University of Maryland, Baltimore, MD
*Purpose: The presumed etiology of primary FSGS is a plasma factor that results in general podocyte dysfunction with partial and/or unpredictable response to immunosuppressive therapy…
2022 American Transplant Congress
Social Determinants of Health Are Associated with Pre-Emptive Wait Listing and Do Not Fully Account for Racial Gap in Early Access to the Waitlist
A. M. Zehner¹, L. A. Cartwright², T. Mupfudze², T. Wilson², A. Placona², B. Carrico²
¹Research Department, United Network for Organ Sharing, Richmond, VA, ²Research Department, UNOS, Richmond, VA
*Purpose: We leveraged a novel data linkage of candidate-level indicators of social determinants of health (SDOH) among kidney waitlist candidates in the United States to…
2022 American Transplant Congress
Predicted Performance of Bayesian-Based Precision Dosing Software for Tacrolimus
A. Seghezzo¹, J. Kerr¹, A. Gupta², A. Ta², L. Powell², A. Feist³
¹University of California San Diego Health, San Diego, CA, ²PrecisePK, San Diego, CA, ³UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA
*Purpose: Bayesian-based precision dosing software (BPDS) has been utilized for therapeutic drug monitoring to optimize medication use. However, BPDS for tacrolimus (TAC) is not routinely…
2022 American Transplant Congress
T and B Cell Response to 3 Dose Covid Vaccine Series for Kidney Transplant Patients on Belatacept
J. Christensen¹, I. Yakubu², D. Kumar¹, D. Cornett³, M. A. Miller³, M. Altrich³, L. Flebbe-Rehwaldt³, R. Thompson¹, G. Gupta¹
¹Internal Medicine, Transplant Nephrology, VCUHealth, Richmond, VA, ²Pharmacy, VCUHealth, Richmond, VA, ³Eurofins Viracor, Lee's Summit, MO
*Purpose: Data shows COVID vaccine response after 2 doses in patients on Belatacept immunosuppression (IS) is low, with reported rates of seroconversion (as measured by…
2022 American Transplant Congress
Development and Validation of an Integrative DD-CFDNA System to Predict Allograft Rejection: A Population Based Study
O. Aubert, R. Brousse, J. Gueguen, M. Racape, C. Lefaucheur, A. Loupy
Paris Translational Center for Organ Transplantation, Paris, France
*Purpose: Post-transplantation patient care requires development and validation of non-invasive biomarkers to improve allograft monitoring and prevention from unnecessary and costly biopsies. Reports have suggested…