Am J Transplant, Volume 22, Suppl 3 Archives - Page 17 of 190 - ATC Abstracts

2022 American Transplant Congress
Three-Way Comparison of Central DSA, %dd-cf DNA, and Molecular Biopsy Findings in the Trifecta Study
P. F. Halloran¹, L. G. Hidalgo², Z. Demko³, A. Prewett³, J. Reeve¹, C. Lawrence⁴, D. Lowe⁴, P. Billings³, .. and the Trifecta Investigators⁵
¹Alberta Transplant Applied Genomics Centre, Edmonton AB, AB, Canada, ²University of Wisconsin, Madison, WI, ³Natera Inc., San Carlos, CA, ⁴One Lambda Inc., West Hills, CA, ⁵., ., AB, Canada
*Purpose: Trifecta (ClinicalTrials.gov #NCT04239703) is a prospective, IRB-approved, consented study of the relationships among three central tests in kidney transplant indication biopsies: molecular biopsy diagnoses…
2022 American Transplant Congress
The Enhanced Recovery After Surgery (ERAS) Program for Donor Hepatectomy; Useful Method for Donor Safety? Or Unnecessary Hindrance?
H. Choi¹, G. Na², H. Park¹, Y. Woo¹, Y. Choi¹, S. Park¹, Y. You¹
¹Seoul St. Mary's hospital, The Catholic University of Korea, Seoul, Korea, Republic of, ²Bucheon St. Mary's hospital, The Catholic University of Korea, Bucheon, Korea, Republic of
*Purpose: Enhanced recovery after surgery (ERAS) programs have been reported to reduce the rate of postoperative complications and shorten hospital stays in liver surgery. However,…
2022 American Transplant Congress
Impact of a Pharmacy-Led Post-Transplant Diabetes Mellitus Clinic in Solid Organ Transplant Recipients
H. Sweiss¹, R. Hall¹, M. Flores², S. Bhayana¹, R. Patel¹, C. Long²
¹University Health - University Hospital, San Antonio, TX, ²College of Pharmacy, University of Incarnate Word, San Antonio, TX
*Purpose: To evaluate the impact of a pharmacy-led post-transplant diabetes mellitus (DM) clinic.*Methods: This retrospective chart review from 08/01/20 to 6/30/21 evaluated adult kidney transplant…
2022 American Transplant Congress
Using mTOR Inhibitor Nanoimmunotherapy to Induce Cardiac Allograft Tolerance in Non-Human Primates
J. M. O¹, P. M. Patel², A. J. Teunissen³, C. L. Miller⁴, T. Costa¹, M. Momodu¹, D. Muldoon¹, A. Dehnadi¹, I. M. Hanekamp¹, V. Pothula⁵, R. Sanchez-Tarjuelo⁶, G. Prevot⁶, W. J. Mulder⁶, J. Allan⁷, J. Ochando⁸, J. Madsen⁹
¹MGH, Boston, MA, ²Emory University, Atlanta, GA, ³Icahn School of Medicine at Mount Sinai, New york, NY, ⁴Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ⁵Icahn School of Medicine at Mount Sinai, New York, NM, ⁶Icahn School of Medicine at Mount Sinai, New York, NY, ⁷Massachusetts General Hospital - Harvard Medical S, Marblehead, MA, ⁸Mount Sinai School of Med, New York, NY, ⁹Massachusetts General Hospital, Boston, MA
*Purpose: Though tolerance of kidney allografts has been consistently achieved using a mixed-chimerism model, cardiac allografts remain resistant to tolerance induction. Lipoprotein-based nanobiologics loaded with…
2022 American Transplant Congress
Polarized Il-6 Secretion from Lymphatic Endothelial Cells Promotes Treg Conversion to Extregs
V. Saxena¹, W. Piao¹, L. Li¹, M. W. Shirkey¹, R. Lakhan¹, S. Walden², K. L. Hippen², B. Blazar², J. S. Bromberg¹
¹University of Maryland School of Medicine, Baltimore, MD, ²University of Minnesota, Minneapolis, MN
*Purpose: Regulatory T cell (Treg) suppressor function and allograft protection depend on maintenance of transcription factor Foxp3 expression and lymphatic migration. Lymphatic endothelial cell (LEC)…
2022 American Transplant Congress
Predictors of Delayed Kidney Graft Function Following Combined Liver and Kidney Transplantation
P. Vincenzi¹, J. Gaynor², R. Vianna³, G. Ciancio³
¹General Surgery, Ospedali Riuniti Marche Nord, Pesaro, Italy, ²General Surgery, Miami Transplant Institute, Miami, FL, ³Transplant Surgery, Miami Transplant Institute, Miami, FL
*Purpose: Combined liver and kidney transplantation (CLKT) improves the survival in liver transplant recipients with renal dysfunction. However, kidney DGF (kDGF) still represents a common…
2022 American Transplant Congress
An Initial Analysis of Baseline Levels of Dd-cfdna After Pancreas Transplantation: A Prospective Study from High-Volume Centers in the United States
A. Yoo¹, I. Qian¹, A. Riedel¹, G. Kibria¹, A. Bartosic¹, R. Soltani², O. Nduanya³, M. Omidi³, J. S. Odorico², P. L. Abrams³, M. Cooper³, J. S. Bromberg¹, J. R. Scalea¹
¹University of Maryland School of Medicine, Baltimore, MD, ²University of Wisconsin School of Medicine, Madison, WI, ³Georgetown University School of Medicine, Washington, DC
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) testing, which has been validated for monitoring kidney transplant (KTx) rejection, may provide an alternative to pancreas biopsy that prevents…
2022 American Transplant Congress
Alcohol Renal Syndrome: Alcohol Related Liver Disease for Liver Transplant is Associated with Renal Dysfunction
J. Lee, K. Okumura, R. Misawa, H. Sogawa, G. Veillette, D. John, B. Partiula, R. Bodin, D. C. Wolf, T. Diflo, S. Nishida
Westchester Medical Center / New York Medical College, Valhalla, NY
*Purpose: Liver transplantation (LT) due to alcohol related liver disease (ALD) has been increasing in the US. Alcohol has been known to increase the risk…
2022 American Transplant Congress
Incidence of Posttransplant Lymphoproliferative Disorder with Belatacept Therapy versus Calcineurin Inhibitor Therapy Alone: Data from One Academic Medical Center
K. Addonizio¹, G. Petrossian¹, A. Hsiao¹, L. Teixeira¹, N. Koizumi², R. James², S. Patel³, R. Plews¹, D. Conti¹, J. Ortiz¹
¹Division of Renal and Pancreatic Transplant Services, Albany Medical Center, Albany, NY, ²George Mason University, Fairfax, VA, ³UMC Las Vegas, Las Vegas, NV
*Purpose: To compare rates of post-transplant lymphoproliferative disorder (PTLD) in patients treated with Belatacept and low-dose calcineurin inhibitors (CNIs) versus patients only treated with standard-dose…
2022 American Transplant Congress
Validation of Shared T Cell Epitope Analysis as a Tool to Detect Preformed Donor-Reactive CD4⁺ Memory T-helper Cells
T. Tomosugi¹, K. Iwasaki², S. Sakamoto³, K. Ftamura¹, M. Okada¹, T. Hiramitsu¹, N. Goto¹, S. Narumi¹, Y. Watarai¹, T. Kobayashi⁴
¹Transplant Surgery, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan, ²Department of Kidney Diseases and Transplant Immunology, Aichi Medical University School of Medicine, Nagoya, Japan, ³Histocompatibility Laboratory, Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan, ⁴Renal Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Japan
*Purpose: Adaptive immunity creates immunological memory after the first response to a specific foreign antigen including HLA. During this response, adaptive immunity memorizes the molecular…