ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Predictors of Short and Long Term Outcomes of Donor After Cardiac Death (DCD) versus Donor After Brain Death (DBD) Kidney Transplantation from Supra Marginal Donors ( D4). A Machine Learning Analysis (MLA) of NHSBT Registry Data Since Year 2000

    H. Sharma1, A. Sharma2, T. Gunawardhane1, B. Devkaran1, K. Kapoor1, S. Mehra1

    1Royal Liverpool University Hospital, Liverpool, United Kingdom, 2Loyola University Chicago, Chicago, IL

    *Purpose: Marginal Donor 4- D4 ( Donor Risk Index ≥1.50 ) Matching was introduced as a part of new Kidney allocation scheme in the UK…
  • 2022 American Transplant Congress

    Effectiveness and Limitations of PK Analysis in Optimization of Immunosuppressive Therapy for Kidney Transplantation

    M. Okumura, K. Ishiyama, S. Ashimine, Y. Miwa, K. Iwasaki, T. Kobayashi

    Division of Kidney Transplantation, Department of Surgery, Aichi Medical University, Nagakute, Japan

    *Purpose: In recent years, significant improvement in organ transplant outcomes have been achieved by using multidrug therapy with several immune monitoring, but the complexity of…
  • 2022 American Transplant Congress

    Third Dose of SARS-CoV-2 mRNA Vaccines Significantly Increases Delta (B.1.617.2) Variant Anti-Spike Antibody Levels in Kidney Transplant Recipients

    A. Al Jurdi1, R. B. Gassen1, T. Borges1, I. T. Lape1, L. Morena1, O. Efe1, Z. Solhjou2, R. El Fekih2, C. Kotton1, J. Azzi2, L. Riella1

    1Massachusetts General Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA

    *Purpose: Emerging SARS-CoV-2 variants may be associated with a higher risk of breakthrough infections compared to wild-type (WT) virus in kidney transplant recipients (KTRs). The…
  • 2022 American Transplant Congress

    Optimizing Kidney Transplant Immunosuppression Using a Phenotypic Personalized Dosing Model

    J. F. Bruner1, N. Padmanabhan2, C. Ho2, A. Zarrinpar1

    1Surgery, University of Florida, Gainesville, FL, 2Bioengineering, University of California, Los Angeles, Los Angeles, CA

    *Purpose: Immunosuppression is essential for preventing rejection and promoting long-term graft survival following solid organ transplantation; it also places patients at risk for infection and…
  • 2022 American Transplant Congress

    Real-Life Prevention of Breakthrough SARS-CoV-2 Infections by mRNA Vaccines in Kidney Transplant Recipients vs Hemodialysis Patients

    D. Rodríguez-Espinosa, E. Montagud-Marrahi, J. Cacho, C. Arana, N. Taurizano, E. Hermida, J. Del Risco, J. Casals, A. Rosario, E. Cuadrado, N. Rodríguez, I. Revuelta, B. Bayès, P. Ventura-Aguiar, F. Cofan, E. Poch, F. Oppenheimer, M. Vera, L. Rodas, F. Maduell, F. Diekmann, A. Cases, J. Broseta, D. Cucchiari

    Nephrology and Renal Transplantation, Hospital Clinic of Barcelona, Barcelona, Spain

    *Purpose: The increased COVID-19 severity observed in kidney transplant recipients (KTR) has been widely reported. In addition, several studies have shown a reduced humoral and…
  • 2022 American Transplant Congress

    Rhinovirus Infection in Solid Organ Transplant Recipients

    G. Motoa1, M. A. Mendoza1, M. Raja1, J. Simkins2, S. Anjan2, E. Martin2, A. Phancao2, N. Sinha2, L. Abbo1, G. Guerra2, Y. Natori2

    1Jackson Memorial Hospital / University of Miami, Miami, FL, 2Miami Transplant Institute – University of Miami, Miami, FL

    *Purpose: Respiratory viral infections are one of the most common infections in solid organ transplant recipients (SOTR), causing significant morbidity and mortality. Limited data is…
  • 2022 American Transplant Congress

    Diagnosis of Acute Graft Rejection After Kidney Transplantation Using Metabolome Analysis by Liquid Biopsy Approach

    H. Iwamoto1, O. Konno1, Y. Kihara1, M. Okihara1, I. Akashi1, T. Ueno1, M. Sugimoto2

    1Department of Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan, 2Research and Development Center for Minimally Invasive and Preemptive Medicine, Tokyo Medical University, Tokyo, Japan

    *Purpose: Presently, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy procedure…
  • 2022 American Transplant Congress

    Do Early Trends of Donor-Derived Cell Free DNA Predict Long Term Kidney Allograft Outcomes?

    S. Park1, K. Guo2, L. Zhao2, C. Rebello2, J. Friedewald2

    1Transplant Nephrology, Northwestern University, Chicago, IL, 2Northwestern University, Chicago, IL

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) has been studied and established for acute rejection detection but the impact of early dd-cfDNA changes on graft outcomes has…
  • 2022 American Transplant Congress

    Predictive Value of Abnormal Hemodynamic Response to Dobutamine Stress Echocardiography in Liver Transplant Recipients

    M. Groose, A. Peotter, L. Hammel

    University of Wisconsin Hospitals and Clinics, Madison, WI

    *Purpose: Dobutamine stress echocardiography (DSE) is an effective tool for perioperative cardiac risk stratification in patients without end-stage liver disease (ESLD). However, DSE is frequently…
  • 2022 American Transplant Congress

    Resource Utilization in Liver Transplant Patients Based on Psychological Evaluation of High Risk vs. Non-High Risk

    K. Barber1, D. Chism2, R. Sauls3, R. Shargo3, M. Gosselin4, S. Mohammed3, K. Robichaux3, A. Kumar5, J. Buggs1

    1Transplant Surgery, Tampa General Hospital, Tampa, FL, 2Lake Erie College of Osteopathic Medicine, Bradenton, FL, 3University of South Florida, Tampa, FL, 4University of Tampa, Tampa, FL, 5Morsani College of Medicine, University of South Florida, Tampa, FL

    *Purpose: Psychological evaluation in liver transplant candidates helps to determine suitability. The psychological risk assessment results in the characterization of either low, medium, or high…
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