Am J Transplant, Volume 22, Suppl 3 Archives - Page 163 of 190 - ATC Abstracts

2022 American Transplant Congress
Alloimmune Recognition Blocks Recipient Macrophage Differentiation into Reparative Subsets
J. Warunek¹, A. Lucas², L. R. Mathews², M. Oberbarnscheidt², F. Lakkis², H. Turnquist²
¹Immunology, Thomas E. Starzl Transplantation Institute, University at Pittsburgh, Pittsburgh, PA, ²Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: Monocytes differentiate into macrophage subsets that orchestrate tissue repair in response to damage signals and local cytokines. After heart transplant (Tx), graft IL-33 acts…
2022 American Transplant Congress
Evs from Patients with Amr Induce Tubular Senescence and Endmt Through Horizontal Transfer of Mirnas
R. Franzin¹, A. Stasi¹, F. Sallustio¹, S. Bruno², G. Merlotti³, M. Quaglia³, G. Grandaliano⁴, P. Pontrelli¹, J. Thurman⁵, G. Camussi², G. Stallone⁶, V. Cantaluppi³, L. Gesualdo¹, G. Castellano⁷
¹DETO, University of Bari, Bari, Italy, ²University of Turin, Turin, Italy, ³University of Piemonte Orientale, Novara, Italy, ⁴Università Cattolica Sacro Cuore, Rome, Italy, ⁵University of Colorado School of Medicine, Aurora, CO, ⁶University of Foggia, Foggia, Italy, ⁷University of Milan, Milan, Italy
*Purpose: Extracellular vesicles (EV) are emerging mediators in several diseases; however, their role in antibody-mediated allograft rejection (AMR) has been poorly investigated.*Methods: Plasma EVs from…
2022 American Transplant Congress
Do Videos Work Better Than Digital Ads at Reaching Audiences? Examining Which Message Types Engage and Encourage Further Exploration of Living Donation
L. A. Davis¹, A. Livingston², A. Waterman³
¹HMH, Houston, TX, ²Multiview, Irving, TX, ³Transplant Research and Education Center, Houston, TX
*Purpose: Testing and examination of media campaigns focused on deceased donor transplant abound. Fewer studies examine the effectiveness of different media strategies at increasing not…
2022 American Transplant Congress
‘Adjuvant Conditioned’ Myeloid Derived Suppressor Cells Prolong Islets Graft Survival Through IL-10 Production
J. Ge¹, L. Ott¹, A. Das¹, J. Markmann², A. Cuenca¹
¹Department of Surgery, Boston Children's Hospital, Boston, MA, ²Division of Transplant Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA
*Purpose: Advances in immunosuppression have been relatively stagnant over the last 2 decades and transplant patients continue to experience morbidity associated with immunosuppression regimens. Through…
2022 American Transplant Congress
Equivalence of Pediatric Paper and Electronic-Based Patient-Reported Outcome Measures: Findings from a Systematic Review
S. Kortbeek¹, A. Pawaria², V. L. Ng¹
¹Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ²Pediatric Hepatology, Gastroenterology and Liver Transplant, Global Hospitals, Mumbai, India
*Purpose: Integration of patient reported outcome measures (PROMs) in routine clinical care reduces utilisation of health care services and improves patient outcomes. Electronic versions of…
2022 American Transplant Congress
Perioperative Cardiovascular Outcomes of Pre-Transplant ECMO in Recipients of Lung Transplant
F. Anjum¹, R. Munshi², A. M. Courtwright¹, M. M. Crespo¹, J. C. Salgado¹, J. D. Christie¹, V. N. Ahya¹, N. Patel¹, D. Hadjiliadis¹, E. Clausen¹, M. Cevasco³, E. E. Cantu³, C. A. Bermudez³, J. M. Diamond¹
¹Pulmonary and Critical Care, University of Pennsylvania, Philadelphia, PA, ²Nassau University Medical Center, East Meadow, NY, ³Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA
*Purpose: Use of extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplant (BTT) has increased over time. While similar one-year and overall survival has…
2022 American Transplant Congress
Contacts Between Organ Donor Families and Their Recipients is Therapeutic for Both Sides in Most Cases
R. Green
Nicholas Green Foundation, La Canada Flintridge, CA
*Purpose: The study's purpose is to discover if making it possible for organ donor families to contact their recipients -- when both sides express the…
2022 American Transplant Congress
Regulatory T and B Cell Responses Are Equally Compromised During Antibody-Mediated Rejection of Kidney Allografts
K. Louis¹, P. Fadakar², C. Macedo², M. Yamada², M. Lucas², X. Gu², A. Zeevi², P. Randhawa², C. Lefaucheur³, D. Metes²
¹Inserm U976, Human Immunology and Immunopathology, Paris, France, ²Surgery, University of Pittsburgh, Pittsburgh, PA, ³Inserm U970, Paris Translational Research Center for Organ Transplantation, Paris, France
*Purpose: Although considerable advances have been made in understanding the cellular effector mechanisms responsible for donor-specific antibody (DSA) generation leading to antibody-mediated rejection (ABMR), the…
2022 American Transplant Congress
Impact of Respiratory Viral Panel Testing on Clinical Decision-Making Among Lung Transplant Recipients Based on Extent of Immunosuppression
A. C. Vostal¹, A. Lynen², S. Chintalapati¹, M. Uehling¹, K. Prakash², A. Shishido¹, J. Baghdadi²
¹University of Maryland Medical Center, Baltimore, MD, ²University of Maryland School of Medicine, Baltimore, MD
*Purpose: Lung transplant recipients (LTRs) are at high risk for complications from viral respiratory infection, including chronic allograft dysfunction. Thus, multiplex molecular testing for respiratory…
2022 American Transplant Congress
Resistance Isn’t Futile: The Independent Effect of Pumping Resistance on Long-Term Kidney Graft Survival
D. Stewart¹, J. Foutz¹, L. Kamal², G. Gupta²
¹United Network for Organ Sharing, Richmond, VA, ²Virginia Commonwealth University Health, Richmond, VA
*Purpose: Kidneys are pumped for therapeutic (to mitigate deleterious effects of ischemia), practical (to facilitate transplant scheduling), and prognostic (to assess organ quality) purposes. Yet…