Am J Transplant, Volume 22, Suppl 3 Archives - Page 158 of 190 - ATC Abstracts

2022 American Transplant Congress
Living Donor Kidney Transplant in Recipients with Glomerulonephritis: Donor Recipient Biologic Relationship and Allograft Outcomes
R. El-Rifai¹, R. Spong¹, A. Bregman¹, K. Swanson¹, S. Jackson², S. Riad¹
¹Nephrology, University of Minnesota, Minneapolis, MN, ²MHealth, Minneapolis, MN
*Purpose: Controversies exist over the impact of donor-recipient biologic relationship on the outcomes of living donor kidney transplant in recipients with glomerulonephritis (GN). The improved…
2022 American Transplant Congress
Focal Distribution of TCMR Causes False Negative Results in Spatially Resolved Molecular Diagnostic Assays
P. Randhawa, Y. Huang
University of Pittsburgh, Pittsburgh, PA
*Purpose: Molecular assays on ~3mm biopsy (BX) fragments of cannot confirm histologic T-cell mediated rejection (TCMR) in ~50% of routine biopsies, and fail to detect…
2022 American Transplant Congress
Race-Based Differences in Simultaneous Liver and Kidney Transplant Utilization and Outcomes
L. Subbaraj¹, J. Lai², G. Cullaro²
¹Department of Internal Medicine, University of California San Francisco, San Francisco, CA, ²University of California San Francisco, San Francisco, CA
*Purpose: Race-based variations in rates of kidney dysfunction exist. We aimed to understand the utilization and impact of simultaneous liver-kidney transplantation (SLKT) by race.*Methods: Patients…
2022 American Transplant Congress
Increase in Exception and Extension Requests for Higher-Urgency Patients Under the New Heart Allocation Policy
J. R. Golbus¹, Y. Ahn², B. K. Nallamothu¹, M. N. Walsh³, D. Zaun², A. Israni², M. Colvin¹
¹University of Michigan, Ann Arbor, MI, ²Hennepin Healthcare Research Institute, Minneapolis, MN, ³Ascension St. Vincent Heart Center, Carmel, IN
*Purpose: In October 2018, a new heart allocation policy was introduced that expanded the number of listing statuses and established a national review board, abolishing…
2022 American Transplant Congress
Post-Acute Sequelae of Sars-Cov-2 Infection in Solid Organ Transplant Recipients
S. Alasfar¹, T. Chiang¹, A. J. Snyder², M. T. Ou¹, B. Boyarsky¹, A. T. Abedon¹, J. L. Alejo¹, W. Cochran¹, J. M. Garonzik-Wang³, D. C. Brennan¹, T. Vannorsdall¹, D. L. Segev¹, R. K. Avery¹
¹Johns Hopkins University, Baltimore, MD, ²University of Washington, Seattle, WA, ³University of Wisconsin, Madison, WI
*Purpose: Post-acute sequelae of SARS-CoV-2 infection (PASC) is an increasingly recognized phenomenon manifested by long lasting cognitive, mental, and physical symptoms. We aimed to estimate…
2022 American Transplant Congress
Donor-Derived IL-33 Plays a Critical Role in Lung Allograft Acceptance
Y. Guo¹, Z. Mei¹, M. Khalil¹, D. Li¹, A. Banerjee¹, A. Gelman², D. Kreisel², A. Krupnick¹
¹Department of Surgery, University of Maryland, Baltimore, Baltimore, MD, ²Washington University School of Medicine in St Louis, Saint Louis, MO
*Purpose: IL-33 is considered an alarmin secreted in response to tissue damage. While it is elaborated by the lung allograft as part of ischemia-reperfusion injury…
2022 American Transplant Congress
RNA-Sequencing Analysis of Kidney Allografts Reveal Heightened NK Cell Activity in Chronic Active Antibody-Mediated Rejection
Y. Shah, E. Varma, S. Rahim, C. Li, C. Snopkowski, C. Hughes, D. M. Dadhania, S. Salvatore, S. V. Seshan, O. Elemento, M. Suthanthiran, T. Muthukumar
Weill Cornell Medicine, New York, NY
*Purpose: The role of NK cells is increasingly recognized in chronic active antibody mediated rejection (caABMR) of the kidney allograft. Treatment of caABMR is challenging…
2022 American Transplant Congress
Desensitization Protocol to Prevent Severe Oliguric Antibody-Mediated Rejection
H. Ishida¹, K. Unagami¹, T. Kamzawa¹, K. Omoto¹, H. Shimizu¹, K. Tanabe²
¹Tokyo Womens, Tokyo 162-8666, Japan, ²Tokyo Women's Medical University, Tokyo, Japan
*Purpose: Antibody-mediated rejection in a case with a positive crossmatch test can be severe and result in sudden onset of oliguria and sometimes, anuria, leading…
2022 American Transplant Congress
Does ABO/HLA Matching Matter in Uterus Transplantation?
L. Johannesson¹, M. Askar¹, A. Wall², G. Testa¹
¹Baylor University Medical Center, Dallas, TX, ²Baylor Scott and White Dallas, Dallas, TX
*Purpose: Uterus transplantation (UTx) is the most commonly performed vascular composite allograft and is rapidly becoming an accepted treatment for absolute uterine-factor infertility (AUFI). There…
2022 American Transplant Congress
Donor-Specific Hyporesponsiveness Following Kidney Transplantation is Explained by Progressive Loss of Donor-Reactive Polyfunctional Cd4+ Effector Memory T Cells
A. C. van der List, N. H. Litjens, M. Klepper, F. Prevoo, M. G. Betjes
Internal Medicine, Erasmus MC, Rotterdam, Netherlands
*Purpose: After kidney transplantation, donor-specific hyporesponsiveness (DSH) develops which is defined as a lowered response of alloreactive T cells to donor antigen while retaining response…