ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    The Evolution of Mortality in Kidney Transplant Recipients at a Single Center in the Era of Covid

    M. M. Eiting, K. Phillips, L. Smith

    University of Utah Health Hospital & Clinics, Salt Lake City, UT

    *Purpose: Mortality secondary to COVID-19 infection is significantly higher in solid organ transplant recipients compared to the general population. Limited data exists evaluating the impact…
  • 2022 American Transplant Congress

    Association of Physical Function and Depression Among Kidney-Pancreas Transplant Recipients Using PROMIS CATs

    A. Yantsis1, W. Ghazi1, A. Norgate1, M. Sanchez1, Y. Sun1, R. Gupta1, R. Ahuja1, I. Mucsi2

    1University Health Network, Toronto, ON, Canada, 2Toronto General Hospital, Toronto, ON, Canada

    *Purpose: The number of kidney-pancreas (KP) transplants is increasing accounting for approximately 6% of all kidney transplants in Canada. In addition to kidney failure and…
  • 2022 American Transplant Congress

    Kidney Transplantation from Deceased Donors with Vaccine-Induced Thrombosis and Thrombocytopenia: An Updated Analysis of the UK Experience

    G. Greenhall, ,. UK VITT Donor Kidney Transplant Study Group

    NHS Blood and Transplant, Bristol, United Kingdom

    *Purpose: Vaccine-induced thrombosis and thrombocytopenia (VITT) is a rare syndrome that has emerged since widespread vaccination against SARS-CoV-2. As a result of the high mortality,…
  • 2022 American Transplant Congress

    The Relative Association of Clinical Variables and Histologic Lesions with Molecular Rejection in Kidney Transplant Biopsies

    M. L. Sikosana1, J. Reeve2, P. F. Halloran2, INTERCOMEX Investigators3

    1University of Alberta, Edmonton, AB, Canada, 2Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 3INTERCOMEX, Edmonton, AB, Canada

    *Purpose: Availability of molecular assessment (MMDx) independent of conventional variables (time, clinical, histologic, and HLA antibody) presents an opportunity to re-assess the relative strength of…
  • 2022 American Transplant Congress

    The Rise in the Number of Eligible Donors for Liver Transplantation Has Been Driven by an Exponential Increase in Marginal Donors

    C. Goff1, M. F. McDonald1, A. Anand1, K. Agahi1, J. Kahla1, A. Jang1, B. Martin1, Z. Shah1, S. Stockum1, R. Vopni2, J. A. Goss1, A. Rana1

    1Baylor College of Medicine, Houston, TX, 2Texas Tech University Health Science Center, Lubbock, TX

    *Purpose: To determine which subcategories of marginal livers have seen advancements in utilization and which have not.*Methods: 181,992 eligible donors listed in the Organ Procurement…
  • 2022 American Transplant Congress

    Antibody Response and Cellular Phenotyping in Kidney Transplant Recipients Following Sars-CoV-2 Vaccination

    N. M. Ali1, J. Miles2, S. Mehta1, V. Tatapudi1, B. Lonze1, E. Weldon1, Z. Stewart1, C. DiMaggio1, J. Allen3, S. Gray-Gaillard3, S. Solis3, M. Tuen3, J. Leonard1, R. Montgomery1, R. Herati3

    1Transplant Institute, NYU Langone Health, New York, NY, 2CareDx, Brisbane, NY, 3NYU Langone Health, New York, NY

    *Purpose: Correlates of protection for SARS-CoV-2 vaccines are not well-established in kidney transplant recipients(KTRs). Studies have highlighted the importance of neutralizing antibodies(Abs), however data suggests…
  • 2022 American Transplant Congress

    What Does It Mean—and How Common is It—For Deceased-Donor Kidneys to ‘Cross in the Air’ En Route to a Recipient?

    G. R. Vece, K. Lindblad, M. Stuart, S. Diallo

    United Network for Organ Sharing, Richmond, VA

    *Purpose: Recent initiatives to broaden organ allocation beyond “local” boundaries (replacing with circle-based or continuous allocation) have brought logistical concerns into sharper focus than ever…
  • 2022 American Transplant Congress

    TIM-4 Identifies Proinflammatory B Cells Expressing an IL-23-Driven “Proinflammatory Module”

    Q. Ding1, V. Sola1, D. Rothstein2

    1University of Pittsburgh, Pittsburgh, PA, 2Thomas E Starzl Transplant Institute, Pittsburgh, PA

    *Purpose: B cells play important Ab-independent roles promoting or inhibiting immune responses through the opposing activity of Bregs and poorly understood effector B cells (Beff)…
  • 2022 American Transplant Congress

    High Incidence Of Anti-HLA DSA And Late Allograft Dysfunction In Solid Organ Transplant Recipients Hospitalized With Covid-19

    J. T. Killian, S. Roman Soto, V. Hauptfeld-Dolejsek, E. B. Levitan, P. M. Porrett, V. Kumar, F. E. Lund, J. A. Houp

    University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Solid organ transplant (SOT) recipients admitted for COVID-19 commonly experience immunosuppression reduction and acute allograft dysfunction. Given the number of SOT patients hospitalized for…
  • 2022 American Transplant Congress

    Impact of Early versus Late Initiation of Sirolimus Regimens on Mortality After Kidney Transplantation: Age-Stratified Analyses of Adult Recipients

    A. Santos1, H. Ibrahim1, M. A. Leghrouz1, X. Wen2

    1University of Florida, Gainesville, FL, 2University of Rhode Island, Kingston, FL

    *Purpose: Observational and meta-analytic studies have associated sirolimus with an increased risk of mortality in kidney transplant (KT) recipients (KTRs). We aimed to examine the…
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