ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Higher Proinflammatory Cytokines Are Associated with Increased Antibody Titer After a Third Dose of SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients

    A. H. Karaba1, X. Zhu1, S. E. Benner1, O. Akinde1, Y. Eby1, K. H. Wang1, S. Saraf2, J. M. Garonzik-Wang3, S. L. Klein1, J. R. Bailey1, A. L. Cox1, J. N. Blankson1, C. M. Durand1, D. L. Segev1, W. A. Werbel1, A. A. Tobian1

    1Johns Hopkins University, Baltimore, MD, 2National Institute of Allergy and Infectious Diseases, Bethesda, MD, 3University of Wisconsin School of Medicine and Health, Madison, WI

    *Purpose: Solid organ transplant recipients (SOTRs) are at increased risk for severe COVID-19 and exhibit lower antibody responses to SARS-CoV-2 vaccines. This study aimed to…
  • 2022 American Transplant Congress

    SARS-CoV-2 Infection is Associated with Greater Neutralizing Antibody Response Compared to Three Doses of Mrna-1273 Vaccine in Solid Organ Transplant Recipients

    V. H. Ferreira, V. Hall, T. M. Marinelli, M. Ierullo, V. Kulasingam, A. Humar, D. Kumar

    University Health Network, Toronto, ON, Canada

    *Purpose: Prior studies suggest that two doses of mRNA vaccine in SOTR may result in lower antibody and T-cell responses relative to levels seen following…
  • 2022 American Transplant Congress

    Additional Dose of SARS-CoV-2 Vaccine Increases Neutralization Capacity in Solid Organ Transplant Recipients

    Y. Yoo1, J. Husson2, T. Iraguha3, S. Niederhaus4, X. Wen5, A. Crane5, A. Carrier5, J. Avruch5, A. Ahuja6, M. Mathew7, S. Dahiya8, A. P. Rapoport8, D. Atanackovic8, K. K. Saharia2

    1Inst of Human Virology, Baltimore, MD, 2Div of Infect Diseases, Univ of Maryland School of Med. and Inst of Human Virology, Baltimore, MD, 3Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD, 4Dept of Surgery, Univ of Maryland School of Med., Baltimore, MD, 5Dept of Surgery, Univ of Maryland Med. Center, Baltimore, MD, 6Dept of Medicine, Univ of Maryland Med. Center, Baltimore, MD, 7Div of Infect. Diseases, Univ of Maryland Med. Center, Baltimore, MD, 8Dept of Medicine, Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD

    *Purpose: Solid organ transplant recipients (SOTR) develop weak antibody responses after SARS-CoV-2 vaccination. Published data on neutralizing activity of plasma, a better measure of protection,…
  • 2022 American Transplant Congress

    The Impact of Maintenance Immunosuppressive Regimen on COVID-19 Outcomes Among Kidney Transplant Patients

    T. V. Sandes-Freitas1, L. Modelli de Andrade2, L. Requião-Moura3, J. Medina-Pestana3, H. Tedesco-Silva3, A. on behalf of Covid-19 KT Brazil Study Group1

    1Universidade Federal do Ceará / Unidade Pesquisa Clínica CH-UFC/EBSERH, Fortaleza, Brazil, 2Universidade Estadual Paulista - UNESP, Botucatu, Brazil, 3Universidade Federal de São Paulo / Hospital do Rim, São Paulo, Brazil

    *Purpose: Compared to azathioprine (AZA), mycophenolate (MPA) is implicated in an increased risk of several viral infections. Contrariwise, mTOR inhibitors (mTORi) are protective. Therefore, the…
  • 2022 American Transplant Congress

    What If Only Days After Dialysis Counted Towards Kidney Candidates’ Qualified Waiting Times?

    G. R. Vece, K. Lindblad, M. Stuart, B. Carrico, D. Stewart, D. Klassen, S. Diallo

    Research, United Network for Organ Sharing, Richmond, VA

    *Purpose: Current kidney policy allows patients who have not yet initiated dialysis to qualify for allocation priority based on the time since a recorded eGFR…
  • 2022 American Transplant Congress

    Eliminating Hepatitis C Positive Status from Kidney Donor Profile Index (KDPI) Calculations Results in Improved Transplant Rates and Outcomes in an Elderly Veteran Population

    R. Lopez-Soler1, A. Thorndyke1, C. Trotter1, A. Abadier2, M. Samra1

    1Surgery, Transplantation, Edward Hines Jr. Veterans Administration Hospital, Hines, IL, 2Surgery, Loyola University Medical School, Maywood, IL

    *Purpose: Overall mortality on the kidney transplant waiting list is higher for older patients. The average age of waitlisted veteran patients is 64, with patients…
  • 2022 American Transplant Congress

    Outcomes Following Renal Transplant with Hepatitis C Viremic Donors in an Elderly Veteran Population with Preemptive Mayvret Therapy

    R. Lopez-Soler1, A. Thorndyke1, C. Trotter1, A. Abadier2, M. Samra1

    1Surgery, Transplantation, Edward Hines Jr. Veterans Administration Hospital, Hines, IL, 2Surgery, Loyola University School of Medicine, Maywood, IL

    *Purpose: Overall mortality on the kidney transplant waiting list is higher for older diabetic patients. The average age of waitlisted veteran patients is 64, with…
  • 2022 American Transplant Congress

    The Effect of Baseline Blood Pressure on Early Graft Function in Deceased Donor Kidney Transplantation

    B. Jun Bae1, C. Oh1, H. Ahn2

    1Department of surgery, Ajou University Medical School, Suwon, Korea, Republic of, 2Department of Anesthesiology and Pain medicine, Ajou University Medical School, Suwon, Korea, Republic of

    *Purpose: The adequate perfusion pressure to the graft is essential for proper graft function in kidney transplantation, especially in deceased donor kidney transplantation. Therefore, the…
  • 2022 American Transplant Congress

    Association Between Increased Overweight at First Year After Kidney Transplantation and Long-Term Kidney Graft Outcome

    H. Choi1, K. Huh2, K. B. Seok3

    1Yonsei University College of Medicine, Seoul, Korea, Republic of, 2Department of Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of, 3Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of

    *Purpose: The obesity is increasing in chronic kidney disease patients and associated with poor renal outcome. The role of inflammation within the adipose tissue in…
  • 2022 American Transplant Congress

    Interventional Radiology Procedures for Complications of Orthotopic Liver Retransplantation: A 22-year Single Center Experience

    A. F. Sayed Ahmed1, B. B. Toskich1, S. A. Mao2

    1Interventional Radiology, Mayo Clinic, Jacksonville, FL, 2Transplant Surgery, Mayo Clinic, Jacksonville, FL

    *Purpose: Liver retransplantation (re-OLT) represents a high risk, resource intense, operation for recipients with failed allografts. We review our single center 22-year experience with re-OLT…
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