ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Humoral Response After a Third Dose of Sars-CoV-2 mRNA Vaccine in Transplant Recipients

    A. E. Woolley, N. Sharma, G. Zhou, A. Kim, E. Ryan, M. Joyce, H. Goldberg, M. Givertz, M. Mehra, E. Woodcome, V. Durney, S. Marshall, K. Townsend, A. Coppolino, S. Tullius, S. Malek, H. Mallidi, L. Baden, A. Chandraker

    Brigham & Women's Hospital, Boston, MA

    *Purpose: Prior studies demonstrated an increased immune response post-3rd COVID-19 vaccine dose when given 1-month post-2nd dose in solid organ transplant recipients (SOT). This study…
  • 2022 American Transplant Congress

    Seroprevalence of HHV8 Among Donors and Recipients with HIV

    P. H. Nambiar1, T. Liang2, J. D. Motter3, W. Werbel3, S. Mehta4, V. Kirchner5, M. Rana6, S. Florman7, J. Odim8, W. Miley9, N. Labo9, D. Whitby9, A. Massie10, D. Segev3, A. Tobian3, C. Durand2

    1Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 2Medicine, Johns Hopkins University, Baltimore, MD, 3Johns Hopkins University, Baltimore, MD, 4New York University Langone Transplant Institute, New York, NY, 5University of Minnesota, Minneapolis, MN, 6Icahn School of Medicine at Mount Sinai, New York, NY, 7Mount Sinai Medical Center, New York, NY, 8National Institute of Health, Bethesda, MD, 9National Cancer Institute, Frederick, MD, 10Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: Kaposi sarcoma (KS) can develop post-transplant via recipient HHV8 reactivation or donor-acquired HHV8. In the general US population, HHV8 seroprevalence is low (1-5%), yet…
  • 2022 American Transplant Congress

    Area Deprivation Index is Associated with Worse Patient Survival Following Adult Liver Transplantation

    J. Hendele1, J. Perkins2, J. Nichols3, A. Dick1

    1Division of Transplant Surgery, Department of Surgery, University of Washington, Seattle, WA, 2Clinical and Bio-Analytics Transplant Laboratory (CBATL), University of Washington, Division of Transplant Surgery, Department of Surgery, Seattle, WA, 3School of Medicine, University of Washington, Seattle, WA

    *Purpose: Area Deprivation Index (ADI) has been utilized as a granular measure of local socioeconomic status for nearly two decades. This study is the first…
  • 2022 American Transplant Congress

    More Than Just Drain Pipes, Pulmonary Lymphatics Play a Pivotal Role in the Development of Bronchiolitis Obliterans Syndrome

    L. Wang1, R. Han2, H. Outtz Reed3, W. W. Hancock2

    1Childrens Hospital of Phila, Philadelphia, PA, 2Children's Hospital of Philadelphia, Philadelphia, PA, 3Weill Cornell, New York, NY

    *Purpose: Chronic allograft dysfunction (CLAD) remains a major determinant of the generally poor long-term outcome of lung transplantation compared to that of other solid organ…
  • 2022 American Transplant Congress

    Living Donor Kidney Transplant in Recipients with Glomerulonephritis: Donor Recipient Biologic Relationship and Allograft Outcomes

    R. El-Rifai1, R. Spong1, A. Bregman1, K. Swanson1, S. Jackson2, S. Riad1

    1Nephrology, University of Minnesota, Minneapolis, MN, 2MHealth, Minneapolis, MN

    *Purpose: Controversies exist over the impact of donor-recipient biologic relationship on the outcomes of living donor kidney transplant in recipients with glomerulonephritis (GN). The improved…
  • 2022 American Transplant Congress

    Focal Distribution of TCMR Causes False Negative Results in Spatially Resolved Molecular Diagnostic Assays

    P. Randhawa, Y. Huang

    University of Pittsburgh, Pittsburgh, PA

    *Purpose: Molecular assays on ~3mm biopsy (BX) fragments of cannot confirm histologic T-cell mediated rejection (TCMR) in ~50% of routine biopsies, and fail to detect…
  • 2022 American Transplant Congress

    Race-Based Differences in Simultaneous Liver and Kidney Transplant Utilization and Outcomes

    L. Subbaraj1, J. Lai2, G. Cullaro2

    1Department of Internal Medicine, University of California San Francisco, San Francisco, CA, 2University of California San Francisco, San Francisco, CA

    *Purpose: Race-based variations in rates of kidney dysfunction exist. We aimed to understand the utilization and impact of simultaneous liver-kidney transplantation (SLKT) by race.*Methods: Patients…
  • 2022 American Transplant Congress

    Increase in Exception and Extension Requests for Higher-Urgency Patients Under the New Heart Allocation Policy

    J. R. Golbus1, Y. Ahn2, B. K. Nallamothu1, M. N. Walsh3, D. Zaun2, A. Israni2, M. Colvin1

    1University of Michigan, Ann Arbor, MI, 2Hennepin Healthcare Research Institute, Minneapolis, MN, 3Ascension St. Vincent Heart Center, Carmel, IN

    *Purpose: In October 2018, a new heart allocation policy was introduced that expanded the number of listing statuses and established a national review board, abolishing…
  • 2022 American Transplant Congress

    Post-Acute Sequelae of Sars-Cov-2 Infection in Solid Organ Transplant Recipients

    S. Alasfar1, T. Chiang1, A. J. Snyder2, M. T. Ou1, B. Boyarsky1, A. T. Abedon1, J. L. Alejo1, W. Cochran1, J. M. Garonzik-Wang3, D. C. Brennan1, T. Vannorsdall1, D. L. Segev1, R. K. Avery1

    1Johns Hopkins University, Baltimore, MD, 2University of Washington, Seattle, WA, 3University of Wisconsin, Madison, WI

    *Purpose: Post-acute sequelae of SARS-CoV-2 infection (PASC) is an increasingly recognized phenomenon manifested by long lasting cognitive, mental, and physical symptoms. We aimed to estimate…
  • 2022 American Transplant Congress

    Donor-Derived IL-33 Plays a Critical Role in Lung Allograft Acceptance

    Y. Guo1, Z. Mei1, M. Khalil1, D. Li1, A. Banerjee1, A. Gelman2, D. Kreisel2, A. Krupnick1

    1Department of Surgery, University of Maryland, Baltimore, Baltimore, MD, 2Washington University School of Medicine in St Louis, Saint Louis, MO

    *Purpose: IL-33 is considered an alarmin secreted in response to tissue damage. While it is elaborated by the lung allograft as part of ischemia-reperfusion injury…
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