2022 American Transplant Congress
Impaired Cellular Immunity and Elevated Myeloid Derived Suppressor Cells in Kidney Transplant Recipients with Impaired Antibody Response to Covid-19 Vaccination
1AdventHealth Transplant Institute, Orlando, FL, 2Plexision, Inc, Pittsburgh, PA
*Purpose: To evaluate post-vaccination cellular and antibody (Ab) immunity after COVID-19 vaccination in single blood samples from 17 kidney transplant (KT) recipients who had received…2022 American Transplant Congress
A Composite Endpoint to Improve Upon the Srtr 5-Tier Rating System
*Purpose: Kidney transplant program performance in the US is monitored with outcome metrics used by regulatory agencies to assess provider quality and by patients to…2022 American Transplant Congress
Combined Genome Wide and Single Nuclei Transcriptomics in Posttransplant Acute Kidney Injury Identifies Early Proinflammatory/Profibrogenic Cell Origin
*Purpose: Kidney transplants offer a unique opportunity to evaluate molecular pathways involved in development and response to acute kidney injury (AKI). This prospective study of…2022 American Transplant Congress
Leveraging Car T Cells To Achieve Desensitization And Enable Transplantation
UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA
*Purpose: Pre-existing allo-antibodies (allo-Abs), that preclude transplant due to the risk of hyperacute rejection, lead to prolonged wait times and high mortality rates. Current desensitization…2022 American Transplant Congress
The Effect of Bariatric Surgery Pre-Transplant on Renal Transplant Outcomes
Surgery, McGill, Montreal, QC, Canada
*Purpose: We compared post-transplant outcomes in patients with morbid obesity undergoing pre-transplant bariatric surgery to non-obese and obese patients without bariatric surgery.*Methods: Adult recipients of…2022 American Transplant Congress
Regional Variation in Early Effects of Acuity Circle-Based Liver Allocation
*Purpose: Liver allocation in the United States was updated on February 4th, 2020, byintroducing the acuity circle (AC)-based model. This study evaluated the early effects…2022 American Transplant Congress
Impact of Long Agonal Duration on Outcomes After Donation After Circulatory Death Lung Transplantation: An Analysis of the United Network of Organ Sharing Database
Department of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Lung transplantation (LTx) using donation after circulatory death (DCD) donors has been well established, however, previous investigators have focused on time from withdrawal of…2022 American Transplant Congress
Passenger Lymphocyte Syndrome Presented as Hemolytic Anemia After Small Bowel Transplantation: A Case Report
*Purpose: The passenger lymphocyte syndrome (PLS) induces hemolytic anemia after minor ABO mismatched organ transplantation. We experienced a case of PLS with hemolysis after small…2022 American Transplant Congress
Analysis of Tissue and Effluent Damage Associated Molecular Patterns Following Hypothermic Oxygenated Machine Perfusion vs Static Cold Storage in Liver Transplantation
Transplant Surgery, Rutgers New Jersey Medical School, Newark, NJ
*Purpose: Hypothermic Oxygenated Machine Perfusion (HMP-O2) results in decreased ischemia/reperfusion injury (IRI) after liver transplantation; however, the molecular pathways of protection are largely unexplored. In…2022 American Transplant Congress
Intrinsic DEPTOR Activity Modulates Treg Subset Differentiation
*Purpose: We have previously reported that DEPTOR activity within CD4+Foxp3+ Tregs increases immunomodulation following transplantation. DEPTOR functions by both stabilization of Foxp3 expression through epigenetic…
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