2022 American Transplant Congress
Single Blind Randomized Controlled Trial Comparing BNT162b2 Vs JNJ-78436735 Vaccine As An Additional Dose After Two Doses Of BNT162b2 Vaccine In Solid Organ Transplant (SOT) Recipients
*Purpose: Even though a high efficacy and immunogenicity of COVID-19 vaccines have been reported in the general population, vaccine immunogenicity is suboptimal in SOT recipients…2022 American Transplant Congress
Single Nuclei RNA-Sequencing Identifies Distinct Immune Cell Profile in Kidney Allograft Fibrosis
*Purpose: A major obstacle after kidney transplantation (KT) is chronic allograft dysfunction characterized by interstitial fibrosis and tubular atrophy (IFTA). Despite extensive research, the cellular…2022 American Transplant Congress
Modification of Gut Microbiota Accelerates Kidney Repair After Experimental Ischemia Reperfusion Injury
Johns Hopkins Medicine, Baltimore, MD
*Purpose: Kidney ischemia reperfusion injury (IRI) leads to changes in gut microbiome, and pre-IR microbiome changes can modify course of experimental tissue injury. There is…2022 American Transplant Congress
Clusterin Protects Kidney Transplants from Ischemia-Reperfusion Injury by Modulating Neutrophil Infiltration
*Purpose: Ischemia-reperfusion injury (IRI) is inevitable during organ transplantation. Clusterin (CLU) has shown to be protective in IRI. Supplementation of storage solution with recombinant CLU…2022 American Transplant Congress
Axl and MerTK Regulate the Activation of Liver Ischemia Reperfusion Injury by Upregulating Il-13 in Kupffer Cells
*Purpose: Ischemia reperfusion injury (IRI) remains an unresolved clinical problem. A sterile inflammatory response drives the disease pathogenesis. Although mechanisms of liver innate immune activation…2022 American Transplant Congress
Risk Factors Associated with ICU Admission and Death in Patients Hospitalized with COVID-19 Differ Between Solid Organ Transplant and Non-Solid Organ Transplant Patients
David Geffen School of Medicine at UCLA, Los Angeles, CA
*Purpose: Despite the large numbers of reports on patient risk factors for poor clinical outcomes with COVID-19, little is known about how these risks may…2022 American Transplant Congress
Recurrent Cytomegalovirus and the Role of Secondary Prophylaxis in Heart and Lung Transplant Recipients
*Purpose: This study aimed to describe the incidence of cytomegalovirus (CMV) recurrence in heart and lung transplant recipients and the effect of secondary prophylaxis (SP)…2022 American Transplant Congress
The US Kidney Allocation System Should Not Allocate En Bloc Kidneys from Deceased Donors < 18 Kg as Equivalent to Top 20% KDPI Single Kidneys
1University of Chicago, Chicago, IL, 2Stanford University, Palo Alto, CA
*Purpose: In December 2020, the US Kidney Allocation System (KAS) revised the allocation rules for deceased donors under 18 kg, stating that both kidneys must…2022 American Transplant Congress
Final Flow and Resistance During Cold Pulsatile Perfusion Preservation Do Have Value in Prediction of Deceased Donor Graft Survival After Adjusting for KDPI
Kidney Transplant, Sacred Heart Hospital, Pensacola, FL
*Purpose: To determine whether cold pulsatile perfusion preservation (CPPP) parameters of flow and resistance provide additional data regarding deceased donor kidney graft survival after adjusting…2022 American Transplant Congress
Bisphosphonates for Fracture Prevention in Kidney Transplant Recipients
*Purpose: Kidney transplant recipients are at increased risk of fracture, however bisphosphonate use has not be shown to lower fracture risk in this population. We…
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