Am J Transplant, Volume 21, Suppl 3 Archives - Page 90 of 139 - ATC Abstracts

2021 American Transplant Congress
Endothelial-to-Myofibroblast Transition (en-mt) and Low Expression of Capillary Vegf Enhance the Development of Interstitial Fibrosis and Glomerulosclerosis Induced by Microvascular Destruction in Antibody-Mediated Rejection (abmr) Patients
B. Ozdemir¹, E. Akcay¹, A. Ok Atilgan¹, M. Haberal²
¹Department of Pathology, Baskent University, Ankara, Turkey, ²Division of Transplantation, Department of General Surgery, Baskent University, Ankara, Turkey
*Purpose: Interstitial fibrosis (IF) and glomerulosclerosis (GS) are the most important cause of graft loss. Although the rate of microvascular destruction (MVD) is similar in…
2021 American Transplant Congress
Lymphotoxin Beta Receptor Regulates Treg Migration and Suppression by Modulating Draining Lymphatic Structure
V. Saxena¹, W. Piao¹, L. Li¹, M. W. Shirkey¹, J. Iyyathurai¹, R. Lakhan¹, R. Abdi², J. Bromberg¹
¹U Maryland, Baltimore, MD, ²Harvard U, Boston, MA
*Purpose: Regulatory T cells (Treg) must migrate from tissues via lymphatic vessels (LV) to the draining lymph node (dLN) to induce tolerance. During migration, Treg…
2021 American Transplant Congress
DSA Causes Mild Molecular ABMR-like Changes in Many Biopsies Not Diagnosed as Rejection
P. F. Halloran¹, K. S. Madill-Thomsen¹, &. the INTERCOMEX Study Group²
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²., ., AB, Canada
*Purpose: In the multicenter study INTERCOMEX, we developed a microarray-based system (MMDx) for diagnosing antibody-mediated and T cell-mediated rejection (ABMR, TCMR) in kidney transplant biopsies…
2021 American Transplant Congress
A Meta-Analysis of Endoscopic Stents in the Treatment of Anastomotic Biliary Strictures After Liver Transplantation
F. Zhou¹, M. Mieth¹, C. Rupp², A. Mehrabi¹, A. Nickkholgh¹
¹Department of General, Abdominal and Transplant Surgery, University of Heidelberg, Heidelberg, Germany, ²Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany
*Purpose: Biliary strictures (BS) are common after orthotopic liver transplantation (OLT). The treatment of choice is endoscopic retrograde cholangiopancreatography (ERCP). Multiple plastic stents (MPS) have…
2021 American Transplant Congress
Beneficial Effects of Argon Inhalation on Reducing Lung Ischemia-reperfusion Injury in Miniature Swine
H. Sahara
Div. Organ Replacement and Xeno Tx, Center for Advanced Biomedical Science and Swine Research, Kagoshima University, Kagoshima, Japan
*Purpose: Noble gases, such as xenon and argon (Ar), are chemically inert but have shown to have cytoprotective effect. In contrast to xenon, Ar is…
2021 American Transplant Congress
Long Term Outcomes of Kidney Donors with Fibromuscular Dysplasia
H. N. Adrogue¹, A. Evans¹, S. A. Hebert¹, H. E. Adrogue¹, D. T. Nguyen², D. Murad¹, E. A. Graviss²
¹Medicine, Houston Methodist Hospital, Houston, TX, ²Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX
*Purpose: Fibromuscular dysplasia (FMD) is not an infrequent finding during kidney donor evaluation. Current guidelines do not provide any recommendations regarding the use of kidneys…
2021 American Transplant Congress
Economic Impact of a Pharmacist-Led Medication Safety Intervention: Report from the Transafe Rx Randomized Controlled Trial
D. Taber, J. Fleming, Z. Su, P. Mauldin, M. Gebregziabher
Med Univ of South Carolina, Charleston, SC
*Purpose: We have previously demonstrated the efficacy of a pharmacist-led, mHealth intervention on reducing medication errors and adverse events leading to reduce hospitalizations in kidney…
2021 American Transplant Congress
Complement Blockade Improves Renal Xenograft Survival in Primates in the Absence of Transgenic Complement Regulatory Proteins
D. A. Faber¹, B. Lovasik¹, A. Matar¹, C. Breeden¹, A. B. Farris², M. Tector³, A. Tector³, A. Adams⁴
¹Surgery, Emory University School of Medicine, Atlanta, GA, ²Pathology, Emory University School of Medicine, Atlanta, GA, ³Surgery, University of Miami, Miami, FL, ⁴Surgery, University of Minnesota, Minneapolis, MN
*Purpose: Complement activation is a major contributor to xenograft rejection. To minimize xenograft injury, complement suppression via insertion of human complement-regulatory transgenes into the donor…
2021 American Transplant Congress
Belatacept for Kidney Transplantation in the Age of Covid19, is it Safe?
J. Pagan¹, S. Anjan², Y. Natori³, A. Fernandez³, R. Zamora-Gonzalez², A. Mattiazzi¹, L. Mendez¹, G. Guerra¹
¹Nephrology, University of Miami, Miami, FL, ²Infectious Diseases, University of Miami, Miami, FL, ³Infectious Disease, University of Miami, Miami, FL
*Purpose: The COVID19 pandemic has affected kidney transplant recipients (KTR) with a wide spectrum of clinical severity. Up to this point, we have solely seen…
2021 American Transplant Congress
Frailty and Short-Term Outcomes in Kidney Transplant
S. Van Arsdale¹, K. Torbert¹, R. Harland², A. Turner², B. Tanriover³, V. Ariyamuthu³
¹Banner University Medical Center, Tucson, AZ, ²Surgery, Banner University Medical Center, Tucson, AZ, ³Internal Medicine, Banner University Medical Center, Tucson, AZ
*Purpose: Studies suggest worse outcomes for frail solid organ transplant recipients. We analyzed post transplant outcomes in relation to frailty.*Methods: We conducted a retrospective study…