ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Acute Kidney Injury Requiring Dialysis in Heart Transplant Recipients is a Risk Factor for Graft Failure and Overall Mortality

    M. A. Merzkani, H. Murad, A. Pottebaum, A. Java, A. Malone, J. Schilling, A. Itoh, R. Delos Santos, T. Alhamad

    Transplant, Washington University, Saint Louis, MO

    *Purpose: Acute Kidney Injury (AKI) is a frequent complication of heart transplantation. However, with recent allocation changes, we have increasingly complex patients with a higher…
  • 2021 American Transplant Congress

    The Metagenomic Landscape of Renal Transplant

    A. Johnson1, G. Karadkhele2, C. Larsen2

    1Emory University, Atlanta, GA, 2Surgery, Emory University, Atlanta, GA

    *Purpose: The selective targeting of T cells in transplant immunosuppression medications leads to a high rate of viral infections. Different immunosuppression regimens have been shown…
  • 2021 American Transplant Congress

    Post-Transplant Idiopathic Immune Complex Glomerulonephritis

    F. Aziz, T. Singh, N. Garg, D. Mandelbrot

    University of Wisconsin, Madison, WI

    *Purpose: The appropriate treatment for post-kidney transplant immune complex glomerulonephritis (ICGN) of unknown cause is unclear.*Methods: From 01/2004 to 12/2018, 71 patients were diagnosed with…
  • 2021 American Transplant Congress

    Liver Dysfunction Following Lung Transplantation

    E. J. Hyzny1, E. G. Chan1, J. P. Ryan1, T. Harano1, M. R. Morrell2, P. G. Sanchez1

    1Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, 2Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: To describe the incidence and risk factors for postoperative hepatic dysfunction (POHD) following lung transplantation (LT) and long-term outcomes for these patients.*Methods: We performed…
  • 2021 American Transplant Congress

    Clinical Correlation of Frailty Measures and Evaluation of Complementary Molecular Frailty Biomarker Candidates in a Prospective National Cohort of Liver Transplant Candidates

    S. Cremen1, M. Robinson2, T. Gallagher1

    1Department of Hepatobiliary and Transplant Surgery, St Vincent's University Hospital, Dublin, Ireland, 2Department of Biology, Maynooth University, Kildare, Ireland

    *Purpose: Frailty is a clinical condition characterized by a loss of physiologic reserve and increased susceptibility to stressors. Molecular frailty biomarkers may reflect the dysregulation…
  • 2021 American Transplant Congress

    Covid-19 Impact of the Pandemic Surge on Patients Waiting for Renal Transplantation at a Single New York City Transplant Center

    G. Boyd, D. Tsapepas, R. Bonifacio, L. Brinkers, C. Brennan, A. Chang, M. Dalangin, L. Lowe, J. K. Mendoza, J. V. Mendoza, C. McNulty, M. Morris, M. Muttiah, K. Nickason, L. Ratner

    Transplant, NYP - Columbia University Medical Center, New York, NY

    *Purpose: There was a critical need to understand the impact that the COVID-19 pandemic had on our patients awaiting transplantation, including infection rates, morbidity, mortality,…
  • 2021 American Transplant Congress

    Intrarenal B-cell Activating Factor (BAFF) Levels are Increased in Transplant Glomerulopathy

    S. Panzer, K. Swanson, G. Pandya, L. Hidalgo, S. Reese

    University of Wisconsin Madison, Madison, WI

    *Purpose: Transplant glomerulopathy (TG), a key feature of chronic active antibody-mediated rejection (caABMR), is associated with allograft failure. B-cell activating factor (BAFF) is a cytokine…
  • 2021 American Transplant Congress

    Reassessing TCMR in Kidney Transplant Indication Biopsies: Emerging Evidence for Partial Exhaustion in Late TCMR

    P. Halloran1, J. Reeve1, &. the INTERCOMEX Study Group2

    1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2., ., AB, Canada

    *Purpose: We rederived the MMDx rejection archetypes in an expanded set of 1679 kidney transplant biopsies to add power and potentially define heterogeneity in TCMR.…
  • 2021 American Transplant Congress

    Reduction in Hospitalizations and Deaths in Covid-19 Positive Abdominal Organ Transplant Recipients Following Implementation of A Protocol for Early Treatment with Bamlanivimab

    A. Ahearn, T. Maw, J. Emamaullee, J. Kim, E. Blodget, J. Kahn, C. Goldbeck, L. Sher, Y. Genyk

    Abdominal Transplantation, Keck Medical Center of USC, Los Angeles, CA

    *Purpose: In December of 2020, our program was identifying up to twenty COVID-19 positive abdominal transplant recipients per week. After seeing our high hospitalization and…
  • 2021 American Transplant Congress

    Laminins Differentially Regulate Adaptive Alloimmune Responses

    L. Li1, M. Shirkey1, W. Piao1, Y. Xiong1, V. Saxena1, T. Zhang1, J. Iyyathurai2, R. Lakhan1, R. Abdi3, J. Bromberg1

    1Surgery, UMB, Baltimore, MD, 2CVID, UMB, Baltimore, MD, 3Harvard University, Boston, MA

    *Purpose: Lymph node (LN) stromal cell expressed laminin α4 (Lama4) and laminin α5 (Lama5) fibers are associated with tolerance and immunity, respectively. They regulate cell…
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