Am J Transplant, Volume 21, Suppl 3 Archives - Page 80 of 139 - ATC Abstracts

2021 American Transplant Congress
Outcomes of Transjugular Intrahepatic Portosystemic Shunts (TIPS) in Dialysis-Dependent ESLD Patients: The ALTA Study
J. Ge¹, J. Boike², M. German³, G. J. Morelli⁴, E. Spengler³, A. Said³, A. S. Lee³, A. Hristov³, A. Desai⁵, T. Couri⁶, S. Paul⁶, C. Frenette⁷, N. Christian-Miller⁷, M. Laurito⁸, E. Verna⁸, U. Rahim⁹, A. Goel⁹, D. Gregory², L. VanWagner², K. P. Kolli¹, J. Lai¹
¹University of California, San Francisco, San Francisco, CA, ²Northwestern Memorial Hospital, Chicago, IL, ³University of Wisconsin, Madison, WI, ⁴University of Florida Health, Gainsville, FL, ⁵Indiana University School of Medicine, Indianapolis, IN, ⁶University of Chicago, Chicago, IL, ⁷The Scripps Clinic, La Jolla, CA, ⁸Columbia University, New York, NY, ⁹Stanford University, Stanford, CA
*Purpose: Data on the outcomes of patients with cirrhosis who require renal replacement therapy (RRT) at the time of transjugular intrahepatic portosystemic shunts (TIPS) is…
2021 American Transplant Congress
Impact of Cypa5 Status on the Clinical and Financial Outcomes of Kidney Transplant
J. Obayemi¹, B. Keating², K. Lentine³, M. Schnitzler³, H. Xiao³, V. Dharnidharka⁴, D. Axelrod⁵
¹Univ of Michigan, Ann Arbor, MI, ²Univ of Pennsylvania, Philadelphia, PA, ³Saint Louis Univ, Saint Louis, MO, ⁴Washington Univ, Seattle, WA, ⁵Univ of Iowa, Iowa City, IA
*Purpose: Pharmacogenetic profiling of transplant recipients has demonstrated marked variation in the metabolism of immunosuppressive medications, particularly tacrolimus. Patients of African ancestry have been found…
2021 American Transplant Congress
Right Kidneys and Kidneys with Complex Anatomy are More Likely to be Transplanted to the Waiting List in a National Kidney Paired Donation Program
N. Osbun¹, A. Thomas², A. Waterman³, J. Veale¹, D. Segev², D. Leeser⁴
¹Urology, University of California Los Angeles, Los Angeles, CA, ²Johns Hopkins University, Baltimore, MD, ³University of California Los Angeles, Los Angeles, CA, ⁴East Carolina University, Greenville, NC
*Purpose: In the era of laparoscopic donor nephrectomy, there is a preference for left kidneys with a single renal artery. In paired exchange, the receiving…
2021 American Transplant Congress
Classification of Distinct Patterns of Ischemic Cholangiopathy Following DCD Liver Transplantation: Distinct Clinical Courses and Long-Term Outcomes from a Multicenter Cohort
K. P. Croome¹, A. K. Mathur², B. Aqel², L. Yang¹, J. K. Heimbach³, T. Taner³, C. B. Rosen³, R. Paz-Fumagalli¹, C. Taner¹
¹Mayo Clinic Jacksonville, Jacksonville, FL, ²Mayo Clinic Arizona, Scottsdale, AZ, ³Mayo Clinic Rochester, Rochester, MN
*Purpose: As the number of donation after circulatory death (DCD) liver transplants (LTs) performed in the United States continues to increase annually, there has been…
2021 American Transplant Congress
The Impact of De Novo Dose-Adjustment Strategies with Tacrolimus XR (LCP-Tac) in Kidney Transplant Recipients
T. Carcella, F. Bartlett, N. Patel, V. Rohan, D. Taber
Medical University of South Carolina, Charleston, SC
*Purpose: LCP-Tac is a once daily formulation of tacrolimus indicated for the prophylaxis of rejection in de novo kidney transplant recipients. It provides less variable…
2021 American Transplant Congress
Sensitized Lung Candidates Experience Reduced Access to Donor Organs
K. Lindblad¹, R. Goff², D. Stewart²
¹UNOS, Richmond, VA, ²UNOS, Richmnd, VA
*Purpose: Most studies of sensitization in transplant candidates have focused on kidney candidates, and unacceptable antigens (UAs) for non-kidney candidates are believed to be underreported.…
2021 American Transplant Congress
Acoustofluidic Device to Remove Donor Specific Antibody in a Sensitized Animal Model
J. Kwun¹, E. David², Y. Gu³, Z. Ma³, M. Kuchibhatla⁴, G. Arepally⁵, T. J. Huang³, E. T. Chambers²
¹Surgery, Duke University, Durham, NC, ²Pediatrics, Duke University, Durham, NC, ³Biomedical Engineering, Duke University, Durham, NC, ⁴Biostatistics and Bioinformatics, Duke University, Durham, NC, ⁵Internal Medicine, Duke University, Durham, NC
*Purpose: Current therapies for antibody-mediated rejection are neither donor-specific nor are they tailored toward children, resulting in premature allograft loss and increased mortality. Apheresis involves…
2021 American Transplant Congress
Cmv Specific Cellmediated Immune Reconstitution During Letermovir Prophylaxis in High Risk Hematopoietic Cell Transplant Recipients
M. Abidi¹, J. Gutman², A. Weinberg²
¹University of Colorado Denver/Anschutz Medical Campus, Aurora, CO, ²University of Colorado Denver, Denver, CO
*Purpose: Patients who are cytomegalovirus (CMV) seropositive (R+) prior to hematopoietic cell transplant (HCT), have a 30% incidence of clinically significant CMV reactivation in the…
2021 American Transplant Congress
Comorbidity Burden is Associated with Increased Waitlist Mortality Among NASH Patients
J. R. Montgomery¹, M. J. Englesbe¹, C. Connelly²
¹Michigan Medicine, Ann Arbor, MI, ²General Surgery, Oregon Health & Science University, Portland, OR
*Purpose: Nonalcoholic steatotic hepatitis (NASH) is an increasing and common indication for liver transplantation. The association between increased comorbidity burden and risk of death on…
2021 American Transplant Congress
Contribution of T-bet Expressing CD27+ CD21- Activated Memory B Cells Poised for Plasma Cell Differentiation to Antibody-mediated Rejection of Kidney Transplants
K. Louis¹, E. Bailly¹, C. Macedo¹, B. Ramaswami¹, X. Gu¹, G. Chalasani¹, A. Zeevi¹, P. Randhawa¹, H. Singh², C. Lefaucheur³, D. Metes¹
¹Surgery, University of Pittsburgh, Pittsburgh, PA, ²Center for Systems immunology, Department of Immunology, University of Pittsburgh, Pittsburgh, PA, ³Human Immunology and Immunopathology, INSERM U976, Paris, France
*Purpose: Alloimmunity triggered by donor-specific antibodies (DSAs) and ensuing development of antibody-mediated rejection (ABMR) are detrimental to organ transplants. Yet, the cellular states underlying B…