Am J Transplant, Volume 21, Suppl 3 Archives - Page 57 of 139 - ATC Abstracts

2021 American Transplant Congress
Combining Oxygenated Cold Perfusion with Normothermic Ex-vivo Perfusion Improves the Outcome of DCD Porcine Kidney Transplantation
L. I. Mazilescu¹, T. Goto¹, R. Rosales¹, Y. Noguchi¹, P. Urbanellis¹, L. A. Robinson², M. Selzner¹
¹Ajmera Transplant Program, Toronto General Hospital, Toronto, ON, Canada, ²Department of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada
*Purpose: Ex-vivo machine perfusion is a novel preservation technique for the storage and assessment of marginal kidney grafts. Normothermic (NEVKP) as well as hypothermic machine…
2021 American Transplant Congress
Donor-derived Cell-free DNA in Upper Extremity Vascular Composite Allograft Recipients
R. Kalsi¹, M. Abuzeineh², J. Littleton¹, J. T. Shores¹, D. S. Cooney¹, C. Cooney¹, R. J. Redett¹, G. Brandacher¹, D. C. Brennan²
¹Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD, ²Nephrology, Johns Hopkins University, Baltimore, MD
*Purpose: Diagnosing rejection in VCA recipients relies on clinical exam and biopsy which are both easily confounded by common causes of skin irritation. dd-cfDNA in…
2021 American Transplant Congress
Gene Expression Profiles Assessed by the Nanostring nCounter® Platform May Differentiate Different Types of Rejection, and Importantly, T-Cell Mediated Rejection from BK Virus Nephropathy
K. R. Degner¹, K. J. Swanson¹, S. Parajuli¹, D. Mandelbrot¹, N. Garg¹, F. Aziz¹, M. Mohamed¹, W. Zhong¹, L. Ptak¹, N. A. Wilson¹, R. Woodward², A. Djamali¹
¹University of Wisconsin, Madison, WI, ²CareDx, Inc., San Francisco, CA
*Purpose: Allograft biopsies are considered the gold standard for diagnosis and therapeutic guidance in kidney transplant recipients. Expanding current biopsy assessments to include gene expression…
2021 American Transplant Congress
The Assesment of Pre-transplant Donor-reactive IL-21 Producing T Cells as a Tool to Identify Patients at Risk for Acute Rejection
A. Mendoza Rojas¹, T. van Gelder², R. de Kuiper¹, D. Reijerkerk¹, M. C. Clahsen-van Groningen³, D. A. Hesselink¹, C. C. Baan¹, N. M. van Besouw¹
¹Internal Medicine, Neprology & Transplantation, Erasmus Medical Center, Rotterdam, Netherlands, ²Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, Netherlands, ³Internal Medicine, Pathology, Erasmus Medical Center, Rotterdam, Netherlands
*Purpose: The measurement of panel-reactive antibodies (PRA) has proven valuable in the transplant setting but it does not account for the presence of donor-reactive memory…
2021 American Transplant Congress
Role of Trugraf Testing in Kidney Allografts Previously Biopsied for Dysfunction
Y. A. Qazi¹, W. Mon¹, C. Choi¹, S. Qazi², M. Smogorzewski¹
¹Keck Medical Center at USC, Los Angeles, CA, ²Keck Medical Center at USC, La Canada Flt, CA
*Purpose: TruGraf®, can be used as an alternative to surveillance biopsies for ruling out “silent” subclinical acute rejections in transplant patients with stable graft function.…
2021 American Transplant Congress
Cellular and Genetic Signatures of Operational Tolerance in Kidney Transplant Recipients Through Single Cell R N A Sequencing Analysis
H. BAE¹, H. Lee², J. Ryu³, B. Chung², E. Oh³
¹Department of Biomedical Science, Graduate School, College of medicine, The Catholic university of Korea, Seoul, Seoul, Korea, Republic of, ²Department of Internal Medicine, Division of Nephrology, College of Medicine, Seoul St. Mary’s hospital, the Catholic University of Korea, Seoul, Korea, Republic of, ³Department of Laboratory Medicine, College of medicine, The Catholic university of Korea, Seoul, Seoul, Korea, Republic of
*Purpose: Patients with operational tolerance do not use immunosuppressants after renal transplantation, but they show stable post-transplant results. We analyzed differently expressed mRNAs and proteins…
2021 American Transplant Congress
Death and Loss to Follow-up in Pediatric Liver Transplant Recipients Transferred to Adult Care: Who is at Risk?
J. P. Stevens¹, S. Gillespie¹, M. Katz¹, L. Hall², V. Kolachala¹, R. Ford³, N. A. Gupta¹
¹Pediatrics, Emory University School of Medicine, Atlanta, GA, ²Transplant Services, Children's Healthcare of Atlanta, Atlanta, GA, ³Internal Medicine, Emory University School of Medicine, Atlanta, GA
*Purpose: With improvements in surgical technique and immunosuppressive regimens, many pediatric liver transplant recipients are surviving to adulthood. Successful transition to an adult provider is…
2021 American Transplant Congress
Primary Graft Dysfunction in a Risk-Stratified vs. Routine Induction Protocol in Heart Transplant Recipients
J. S. van Zyl¹, H. Zafar¹, P. M. Nguyen², J. Felius¹, T. Sam³, S. A. Hall³
¹Baylor Scott & White Research Institute, Dallas, TX, ²Texas A&M University College of Medicine Health Science Center, Dallas, TX, ³Baylor Scott & White Health, Dallas, TX
*Purpose: Treatment of left ventricular primary graft dysfunction (PGD-LV) is supportive in nature. We aim to evaluate whether a change in induction protocol from a…
2021 American Transplant Congress
Covid Studies in 208 Patients with Consent for Donation
A. L. Friedman, C. Ezzell, K. Delli Carpini
LiveOnNY, New York, NY
*Purpose: To prevent transmission of SARS CoV 2 via solid organ donation from deceased donors.*Methods: Comprehensive medical and psychosocial evaluation of potential deceased organ donors…
2021 American Transplant Congress
Weathering the Cytokine Storm: Therapeutic Plasma Exchange for the Management of Severe Covid19 in Solid Organ Transplant Recipients
A. Mattiazzi¹, J. Pagan¹, L. A. Mendez Castaner², A. Fernandez¹, R. Zamora Gonzalez¹, J. Simkins¹, L. Preczewski¹, Y. Natori¹, S. Anjan¹, G. Guerra¹
¹Miami Transplant Institute, Miami, FL, ²Miami Trasnplant Institute, Miami, FL
*Purpose: The treatment of SARS-CoV-2 associated pneumonia in solid organ transplant recipients (SOTr) continues to be under investigation. Timely control of the cytokine release storm…