Am J Transplant, Volume 21, Suppl 3 Archives - Page 53 of 139 - ATC Abstracts

2021 American Transplant Congress
Feasibility of a Virtual Renal Transplant Simulation Model for Surgical Trainees in the Covid Era
O. Eletta¹, S. Iacono¹, D. Walls¹, S. Puri², B. Perry¹, C. Anderson¹, M. J. Nguyen³, A. Bongu²
¹General Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, ²Transplant, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, ³Transplant Institute, Loma Linda University Medical Center, Loma Linda, CA
*Purpose: The COVID-19 pandemic and social distancing requirements has affected our resident education curriculum. We developed a virtual renal transplant simulation session to simulate renal…
2021 American Transplant Congress
Donor-specific Anti-HLA Alloantibody in Kidney Transplant Recipients with COVID-19 Exhibit a Different Immunoglobulin Class and Subclass Profile When Compared to Anti-SARS-CoV-2 Antibodies
A. Girnita¹, L. Wang¹, M. Fernandez-Vina¹, E. Woodle², P. Ahearn¹, T. Yalamarti¹, M. Menon³, Y. Azzi⁴, M. Melcher¹, R. Bray⁵, H. Gebel⁵, E. Akalin⁴, P. Cravedi³, J. S. Maltzman¹
¹Stanford University, Palo Alto, CA, ²University of Cincinnati, Cincinnati, OH, ³Icahn School of Medicine, NYC, NY, ⁴Einstein School of Medicine, NYC, NY, ⁵Emory University, Atlanta, GA
*Purpose: Both anti-HLA and anti-SARS-CoV-2 antibodies target protein antigens. The aim of the present study was to compare the class and subclass profile of such…
2021 American Transplant Congress
A Single Nucleotide Polymorphism within the FCGR3A 158 F/V Gene is Associated with Decreased Survival of Renal Allografts with Chronic Active Antibody-Mediated Rejection
N. H. Litjens, A. M. Peeters, J. A. Kal-van Gestel, M. Klepper, M. G. Betjes
Internal Medicine, Nephrology and Transplantation, Erasmus MC, University Medical Center, Rotterdam, Netherlands
*Purpose: Long-term allograft survival has shown little improvement over the last decades. An important factor compromising long-term allograft survival in kidney transplantation is chronic active…
2021 American Transplant Congress
Clinical Outcomes and Racial Impact of HLA Matching in the Australian Deceased Donor Kidney Transplantation Program, 2000-2018
M. Gramlick, M. Heer
Department of Surgery, John Hunter Hospital, Newcastle, Australia
*Purpose: The Australian deceased donor (DD) kidney transplant program places a large emphasis on HLA matching despite a known disadvantage to ethnic minority groups. We…
2021 American Transplant Congress
Steroid-free Immunosuppression in Heart-Kidney Transplant Patients: Is It Safe?
R. Skorka, J. Patel, M. Kittleson, N. Patel, T. Singer-Englar, A. Velleca, B. Azarbal, D. Chang, E. Kransdorf, L. Czer, D. Megna, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Simultaneous heart and kidney transplantation (sHKTx) has increased in numbers over the past 10 years. There are reports that the kidney protects the heart…
2021 American Transplant Congress
COVID-19 in the Kidney Transplant Waitlist Population
A. C. Johnson¹, C. P. Larsen¹, H. Gebel², R. Bray²
¹Surgery, Emory University, Atlanta, GA, ²Pathology, Emory University, Atlanta, GA
*Purpose: Through banked serum samples from transplant candidates across Georgia, we characterize the prevalence, timing, and duration of SARS-CoV-2 seropositivity and investigate the impact on…
2021 American Transplant Congress
Racial and Ethnic Disparities in Pediatric Kidney Transplantation – Has KAS Made a Difference?
O. Charnaya¹, S. Yu², A. Goldberg³, J. Garonzik-Wang², D. Segev², P. Verghese⁴
¹Pediatrics, Johns Hopkins University, Baltimore, MD, ²Transplant Surgery, Johns Hopkins University, Baltimore, MD, ³University of Manitoba, Winninpeg, MB, Canada, ⁴Northwestern University Feinberg School of Medicine, Chicago, IL
*Purpose: Racial and ethnic minority pediatric transplant candidates have known disparities in access to kidney transplantation. The Kidney Allocation System (KAS), implemented in 2014, was…
2021 American Transplant Congress
A Molecular Classifier Identifies Antibody-Mediated Rejection-Associated Changes in Lung Transplant Biopsies
K. S. Madill-Thomsen¹, K. M. Halloran², M. Parkes¹, P. F. Halloran¹, &. the INTERLUNG Study Group³
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³., ., AB, Canada
*Purpose: Identifying lung transplant antibody-mediated rejection (ABMR) has been controversial. We compared gene expression in donor-specific antibody (DSA) positive vs. DSA negative lung transbronchial biopsies…
2021 American Transplant Congress
Donor-Recipient BSA Matching is Prognostically Significant in Solitary and En-bloc Kidney Transplantation from Pediatric Circulatory Death Donors
C. J. Little, A. A. Dick, J. D. Perkins, J. D. Reyes
Department of Surgery, University of Washington, Seattle, WA
*Purpose: The purpose of this study was to evaluate the pernicious effects of inadequate functional nephron mass in size disparate donation after cardiac death (DCD)…
2021 American Transplant Congress
Treg Engagement of Lymphotoxin Beta Receptor in Lymphatic Endothelial Cells is Required for Allograft Protection
V. Saxena¹, W. Piao¹, L. Li¹, Y. Xiong¹, M. W. Shirkey¹, J. Iyyathurai¹, R. Lakhan¹, R. Abdi², J. Bromberg¹
¹U Maryland, Baltimore, MD, ²Harvard U, Boston, MA
*Purpose: Sequential migration of regulatory T cells (Treg) from graft to afferent lymphatics and lymph nodes (LN) is needed for Treg suppressive function. Migration requires…