2021 American Transplant Congress
SARS-CoV-2 Infection in Solid Organ Transplant Recipients: A Retrospective Cohort Study
Infectious Diseases, University of Massachusetts, Worcester, MA
*Purpose: Initial studies of COVID-19 in solid organ transplant (SOT) recipients demonstrated high mortality rates, but more recent comparative data shows contradictory results.*Methods: We evaluated…2021 American Transplant Congress
Impact of Covid-19 Infection on Tacrolimus Levels in Solid Organ Transplant Recipients
Loyola University Medical Center, Maywood, IL
*Purpose: Immunocompromised patients are considered to be at high-risk for infection with SARS-CoV-2 (COVID-19). There have been observations within the transplant community that patients infected…2021 American Transplant Congress
A Multi-institutional Study of Renal Outcomes in Uterus Transplantation
*Purpose: Pregnancy and calcineurin inhibitor-based immunosuppression represent potential renal stressors for uterus transplant (UTx) recipients, many of whom have Mayer-Rokitanksy-Kuster-Hauser (MRKH) syndrome and associated renal…2021 American Transplant Congress
Polyfunctional T-cell Impairment to Sars-cov-2 Coronavirus in Solid Organ Transplant Recipients with Acute Covid-19 Infection
*Purpose: The emerged COVID-19 pandemic caused by SARS-CoV-2 has paralyzed the world, due to its high infectivity and fatal outcomes, especially among more vulnerable individuals.…2021 American Transplant Congress
The Impact of Splenectomy on Living Donor Liver Transplantation Using Small Grafts
Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Simultaneous splenectomy with living donor liver transplantation (LDLT) is widely used in Asian countries to decrease the risk of small-for-size syndrome (SFSS). However, the…2021 American Transplant Congress
Two Hundred Total Pancreatectomy with Islet Autotransplantation Cases: A Single Center Experience
1Baylor University Medical Ctr, Dallas, TX, 2Virginia Commonwealth University, Richmond, VA
*Purpose: Total pancreatectomy and islet autotransplantation (TPIAT) for patients with uncontrolled chronic pancreatitis has been performed at our center from 2006 and the number of…2021 American Transplant Congress
Intensive Blood Pressure Control Preserves Kidney Allograft Function
*Purpose: Kidney transplant recipients (KTRs) are at higher risk of major adverse cardiovascular events compared to the general population, with HTN being a crucial risk…2021 American Transplant Congress
T Cell Repertoire Diversity in HCV-Associated Hepatocellular Carcinoma Patients Waitlisted for Liver Transplantation and Receiving Liver-Directed Therapy
Ochsner Health, New Orleans, LA
*Purpose: T cell receptor (TCR) sequencing in hepatocellular carcinoma (HCC) patients revealed a diverse TCR repertoire in hepatitis B-associated HCC-infiltrating T cells. In this study,…2021 American Transplant Congress
A Multimodal Interrogation of Human Renal Allografts
1Weill Cornell Medicine - NYPH, New York, NY, 2CareDx, New York, NY
*Purpose: Development and validation of noninvasive biomarkers of kidney allograft rejection should improve transplant outcomes. CTOT-04 study validated urinary cell mRNA signature (CTOT04-Sig) for T-cell…2021 American Transplant Congress
Prevalence of Diabetic Changes on Kidney Allograft Biopsies of Normoglycemic Simultaneous Pancreas-Kidney Transplant Recipients
Johns Hopkins University, Baltimore, MD
*Purpose: Small studies suggest that achieving normoglycemia with simultaneous pancreas-kidney transplant (SPK) prevents the development of diabetic nephropathy (DN) among type 1 diabetics (T1DM). However,…
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