Am J Transplant, Volume 21, Suppl 3 Archives - Page 47 of 139 - ATC Abstracts

2021 American Transplant Congress
Cross-Circulation for Extracorporeal Liver Support in a Swine Model
W. K. Wu¹, A. Tumen¹, J. W. Stokes², R. Ukita², A. E. Hozain³, C. R. Flynn², M. J. Lee³, J. R. Talackine², N. L. Cardwell², J. A. Reimer³, M. Pinezich³, C. Benson², G. Vunjak-Novakovic³, S. P. Alexopoulos², M. Bacchetta²
¹co-first authors, Vanderbilt University Medical Center, Nashville, TN, ²Vanderbilt University Medical Center, Nashville, TN, ³Columbia University Medical Center, New York, NY
*Purpose: Although machine perfusion has gained momentum as an organ preservation strategy in liver transplantation, significant organ shortages and waitlist mortality persist, highlighting unmet needs…
2021 American Transplant Congress
CT-measured Cortical Volume Ratio is an Alternative to Nuclear Medicine Split Scan Ratio Among Living Kidney Donors
J. Montgomery, C. Brown, A. Zondlak, K. Walsh, J. Kozlowski, A. Pinsky, E. Herriman, J. Sussman, Y. Lu, E. Stein, P. Shankar, R. Sung, K. Woodside
Michigan Medicine, Ann Arbor, MI
*Purpose: The 125I-iothalamate clearance and 99mTc-DTPA split scan nuclear medicine studies are used among living kidney donor candidates to determine mGFR and split-scan ratio (SSR).…
2021 American Transplant Congress
Noninferiority Outcomes Among Undocumented Immigrant Kidney Transplant Recipients in California
H. Ichii¹, N. Eguchi¹, E. Tantisattamo², U. Reddy², A. Ferrey², D. Dafoe¹
¹Surgery, University of California Irvine, Orange, CA, ²Medicine, University of California Irvine, Orange, CA
*Purpose: There are over 2 million undocumented immigrants (UI) in California, where currently, all individuals regardless of immigration status have equal access to kidney transplant(KT).…
2021 American Transplant Congress
Managing the Costs of Routine Follow-up Care After Living Kidney Donation: A Survey of Contemporary Experience, Practice & Challenges
K. Lentine¹, G. McNatt², R. Howey³, C. Thomas², R. Hays⁴, U. Lebron-Banks⁵, S. Ainapurapu¹, A. Tietjen⁶
¹Saint Louis University, Saint Louis, MO, ²Univ. Iowa, Iowa City, IA, ³Toyon Associates, Concord, CA, ⁴Univ. Wisconsin, Madison, WI, ⁵New York-Presbyterian Hosp., New York, NY, ⁶St. Barnabas, Livingston, NJ
*Purpose: Organ Procurement and Transplantation Network (OPTN) Policy mandates that living kidney donor (LKD) programs collect and report clinical and laboratory follow-up information for living…
2021 American Transplant Congress
Iatrogenic Sodium Exposure in Hospitalized Patients with Liver Disease
P. Klem¹, R. Mbangu Kot Mbau², B. Crowther¹, V. Lewis¹, S. Lin¹, E. Patrick³, A. Nadrash¹, K. Schoeppler¹, I. Kim¹
¹Pharmacy, University of Colorado Hospital, Aurora, CO, ²Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, ³Transplant Services, University of Colorado Hospital, Aurora, CO
*Purpose: Numerous medications administered in the hospital setting may contain hidden/additional amounts of sodium in the drug itself and via intravenous (IV) diluents or admixtures.…
2021 American Transplant Congress
Wave of the Future: Expanding Role and Necessity of the Dedicated Procurement Surgeon
C. Strom, B. Cimsit, H. Nelson, F. Delmonico
New England Donor Services, Waltham, MA
*Purpose: To evaluate the quantitative and qualitative benefits of a dedicated procurement surgeon (DPS) across the transplant spectrum, including the DPS technical performance value for…
2021 American Transplant Congress
DAP12 Promotes Liver DC Tolerogenicity by Negative Regulation of the CGAS-STING-IFN I Pathway
Y. Zheng¹, J. Long², N. Ryosuke¹, L. Peng³, F. Peng³, A. Thomson¹
¹Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, ²Department of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China, ³Department of Kidney Transplantation, The Second Xiangya Hospital of Central South University, Changsha, China
*Purpose: Constitutive expression of comparatively high levels of DNAX-activating protein of 12KDa (DAP12) by liver myeloid dendritic cells (mDCs) has been implicated in their immune…
2021 American Transplant Congress
Single Cell RNA Sequencing Reveals a Global Increase in Inflammatory Gene Signature Following Normothermic Ex Vivo Liver Perfusion
K. Carlson, J. Pavan-Guimaraes, B. Verhoven, J. Verhagen, F. Najmabadi, D. P. Al-Adra
Surgery, University of Wisconsin, Madison, WI
*Purpose: Normothermic ex vivo liver perfusion (NEVLP) provides an exciting system for improved organ preservation and optimized therapeutic agent delivery to a donor liver prior…
2021 American Transplant Congress
Hypoxia Inducible Factor 1á (HIF-1á) Regulates Carcinoembryonic Antigen-related Cell Adhesion Molecule-1 (CEACAM1) Splice Isoforms to Protect Against Ischemic Injury in Mouse and Human Liver Transplantation
K. J. Dery, H. Kojima, K. Kadono, H. Hirao, J. W. Kupiec-Weglinski
The Dumont-UCLA Transplantation Center, Los Angeles, CA
*Purpose: CEACAM1 (CC1) is a transmembrane glycoprotein that undergoes extensive alternative splicing (AS) to generate CC1-S and CC1-L. It is currently unclear which of these…
2021 American Transplant Congress
Effects of IL-18 on Key Post-Translational Modifications of Human Foxp3 and Innate Immunity
T. Akimova¹, L. M. Christensen¹, Z. Wang², M. H. Levine², W. W. Hancock¹
¹CHOP & University of Pennsylvania, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA
*Purpose: Most of our ideas about Treg cells are extrapolated from findings in mice, with actual clinical data typically involving flow cytometric enumeration of CD4+FOXP3+…