ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Outcomes of Simultaneous Pancreas-Kidney Transplants from Donation After Circulatory Death Donors in the UK: A National Registry Analysis

    N. Karydis1, M. Ibrahim2, C. Counter2, J. Casey3, P. Friend4, C. Watson5, C. Callaghan1

    1Nephrology and Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom, 2NHS Blood and Transplant, Bristol, United Kingdom, 3Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom, 4Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, 5Department of Surgery, Addenbrooke's Hospital and Cambridge NIHR Biomedical Research Campus, Cambridge, United Kingdom

    *Purpose: The UK is a world leader in the use of pancreases from donation after circulatory death (DCD) donors. However, there is a perception that…
  • 2021 American Transplant Congress

    Growth Differentiation Factor 15 Predictor Value is Superior to Troponin I in the Evaluation of Kidney Transplant Candidates

    M. de Cos Gomez1, M. Garcia Unzueta2, A. Benito Hernandez1, J. Mazon Ruiz1, M. Perez Arnedo1, A. Aguilera Fernandez1, R. Valero San Cecilio1, J. Ruiz San Millan1, E. Rodrigo Calabia1

    1Nephrology, Marques de Valdecilla University Hospital - IDIVAL, Santander, Spain, 2Clinical Analysis, Marques de Valdecilla University Hospital - IDIVAL, Santander, Spain

    *Purpose: Pretransplant cardiac troponin I (cTNI) has demonstrated its predictor value of survival after kidney transplant in previous studies. Growth differentiation factor 15 (GDF-15) is…
  • 2021 American Transplant Congress

    Adjuvant Immunotherapy for Liver Transplant Recipients with Hepatocellular Carcinoma Using Donor Liver-derived Natural Killer Cells

    M. Ohira1, R. Hotta1, Y. Imaoka1, K. Sato1, N. Tanimine1, Y. Tanaka1, S. Nishida2, A. Tzakis2, H. Ohdan1

    1Hiroshima University, Hiroshima, Japan, 2University of Miami, Miami, FL

    *Purpose: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is an indication for liver transplantation (LT). Immunosuppressive regimens currently used after…
  • 2021 American Transplant Congress

    Utility of Screening-Bead Assay in Post-Transplant Testing of Donor-Specific Antibodies (DSA) and Antibody-mediated Rejection (ABMR) in Renal Allografts

    A. Agrawal1, E. Dijke2, A. Murray3, P. Campbell3

    1Transplant Nephrology, Mayo Clinic, Rochester, MN, 2Lab. Medicine and Pathology, University of Alberta Hospital, Edmonton, AB, Canada, 3Division of Nephrology, Dept. of Medicine, University of Alberta Hospital, Edmonton, AB, Canada

    *Purpose: ABMR is a major cause of poor long-term graft survival. Though post-transplant monitoring of HLA DSAs can aid in risk stratification and optimizing immunosuppression,…
  • 2021 American Transplant Congress

    Peri-covid Trends on the Intestinal Transplant Waiting List

    M. L. Samoylova1, S. Jafri2, M. I. Fiel3, S. Horslen4, A. Mavis5, T. Schiano6, B. Summers7, M. C. Segovia8

    1Surgery, Duke University, Durham, NC, 2Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, 3Pathology, Mount Sinai, New York, NY, 4Transplantation, Seattle Children's Hospital, Seattle, WA, 5Pediatric Gastroenterology, Duke University, Durham, NC, 6Hepatology, Mount Sinai Medical Center, New York, NY, 7Pharmacy, Henry Ford Hospital, Detroit, MI, 8Gastroenterology, Duke University, Durham, NC

    *Purpose: We aim to describe the trends in intestinal and multivisceral transplant waiting list activity and outcomes before and after the COVID-19 pandemic.*Methods: We used…
  • 2021 American Transplant Congress

    Development and Validation of a Novel Peripheral Blood Based Gene Signature for Acute Rejection Following Renal Transplantation

    D. Zhang, Y. Wang, X. Hu

    Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

    *Purpose: The aim of this study is to utilize advanced machine learning methods to construct a peripheral blood-based gene signature for acute rejection following kidney…
  • 2021 American Transplant Congress

    Findings from the Bareto Study: Associations Between Chronic Vascular Changes and 10-year Transplant Graft Outcomes

    L. Kamal1, D. Stewart2, J. Foutz2, H. McGehee2, P. Saravanane1, S. Yu1, R. Yusfi1, G. Gupta1

    1Virginia Commonwealth University, Richmond, VA, 2UNOS, Richmond, VA

    *Purpose: As part of a broader study on Biopsy, Anatomy, and Resistance Effects on Transplant Outcomes (BARETO), we aim to characterize the poorly understood relationship…
  • 2021 American Transplant Congress

    DSA is Associated with Molecular Changes in Many Hearts with Minor Abnormalities but Not Diagnosed as Antibody-Mediated Rejection

    P. Halloran1, K. S. Madill-Thomsen1, &. the INTERHEART Study Group2

    1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2., ., AB, Canada

    *Purpose: We previously developed a microarray-based diagnostic system (MMDx) for heart transplant endomyocardial biopsies, measuring gene expression and interpreting antibody-mediated and T cell-mediated rejection (ABMR,…
  • 2021 American Transplant Congress

    Influence of Induction Therapy and Antiretroviral Regimen on Outcomes in HIV Positive Renal Transplant Recipients

    C. Rogers Marks1, C. Durand2, J. Hand3, M. Abidi4, M. Malinis5, B. Barnaba2, H. Patel6, C. D. Alonso6

    1Massachussetts General Hospital, Boston, MA, 2Johns Hopkins Medical Center, Baltimore, MD, 3Ochsner Medical Center, New Orleans, LA, 4Univ. of Colorado, Aurora, CO, 5Yale, New Haven, CT, 6Beth Israel Deaconess Medical Center, Boston, MA

    *Purpose: Transplantation of HIV+ individuals has become more common over the past decade with increasing data supporting good outcomes. Questions remain regarding the impact of…
  • 2021 American Transplant Congress

    Kidney Donor Risk Index: Significance as a Predictor of Kidney Transplant Outcomes Beyond Allograft Survival, Analysis of 18 Adjusted Regression Models Involving Adult Deceased Donor Kidney Recipients

    A. Santos, E. Bueno, M. A. Leghrouz

    University of Florida, Gainesville, FL

    *Purpose: We aimed to study the role of kidney donor recipient index (KDRI) as a predictor for multiple transplant-related outcomes in adult deceased-donor (DD) kidney…
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