Am J Transplant, Volume 21, Suppl 3 Archives - Page 45 of 139 - ATC Abstracts

2021 American Transplant Congress
Adjuvant Immunotherapy for Liver Transplant Recipients with Hepatocellular Carcinoma Using Donor Liver-derived Natural Killer Cells
M. Ohira¹, R. Hotta¹, Y. Imaoka¹, K. Sato¹, N. Tanimine¹, Y. Tanaka¹, S. Nishida², A. Tzakis², H. Ohdan¹
¹Hiroshima University, Hiroshima, Japan, ²University of Miami, Miami, FL
*Purpose: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is an indication for liver transplantation (LT). Immunosuppressive regimens currently used after…
2021 American Transplant Congress
Utility of Screening-Bead Assay in Post-Transplant Testing of Donor-Specific Antibodies (DSA) and Antibody-mediated Rejection (ABMR) in Renal Allografts
A. Agrawal¹, E. Dijke², A. Murray³, P. Campbell³
¹Transplant Nephrology, Mayo Clinic, Rochester, MN, ²Lab. Medicine and Pathology, University of Alberta Hospital, Edmonton, AB, Canada, ³Division of Nephrology, Dept. of Medicine, University of Alberta Hospital, Edmonton, AB, Canada
*Purpose: ABMR is a major cause of poor long-term graft survival. Though post-transplant monitoring of HLA DSAs can aid in risk stratification and optimizing immunosuppression,…
2021 American Transplant Congress
Peri-covid Trends on the Intestinal Transplant Waiting List
M. L. Samoylova¹, S. Jafri², M. I. Fiel³, S. Horslen⁴, A. Mavis⁵, T. Schiano⁶, B. Summers⁷, M. C. Segovia⁸
¹Surgery, Duke University, Durham, NC, ²Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, ³Pathology, Mount Sinai, New York, NY, ⁴Transplantation, Seattle Children's Hospital, Seattle, WA, ⁵Pediatric Gastroenterology, Duke University, Durham, NC, ⁶Hepatology, Mount Sinai Medical Center, New York, NY, ⁷Pharmacy, Henry Ford Hospital, Detroit, MI, ⁸Gastroenterology, Duke University, Durham, NC
*Purpose: We aim to describe the trends in intestinal and multivisceral transplant waiting list activity and outcomes before and after the COVID-19 pandemic.*Methods: We used…
2021 American Transplant Congress
Development and Validation of a Novel Peripheral Blood Based Gene Signature for Acute Rejection Following Renal Transplantation
D. Zhang, Y. Wang, X. Hu
Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
*Purpose: The aim of this study is to utilize advanced machine learning methods to construct a peripheral blood-based gene signature for acute rejection following kidney…
2021 American Transplant Congress
Findings from the Bareto Study: Associations Between Chronic Vascular Changes and 10-year Transplant Graft Outcomes
L. Kamal¹, D. Stewart², J. Foutz², H. McGehee², P. Saravanane¹, S. Yu¹, R. Yusfi¹, G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²UNOS, Richmond, VA
*Purpose: As part of a broader study on Biopsy, Anatomy, and Resistance Effects on Transplant Outcomes (BARETO), we aim to characterize the poorly understood relationship…
2021 American Transplant Congress
DSA is Associated with Molecular Changes in Many Hearts with Minor Abnormalities but Not Diagnosed as Antibody-Mediated Rejection
P. Halloran¹, K. S. Madill-Thomsen¹, &. the INTERHEART Study Group²
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²., ., AB, Canada
*Purpose: We previously developed a microarray-based diagnostic system (MMDx) for heart transplant endomyocardial biopsies, measuring gene expression and interpreting antibody-mediated and T cell-mediated rejection (ABMR,…
2021 American Transplant Congress
Influence of Induction Therapy and Antiretroviral Regimen on Outcomes in HIV Positive Renal Transplant Recipients
C. Rogers Marks¹, C. Durand², J. Hand³, M. Abidi⁴, M. Malinis⁵, B. Barnaba², H. Patel⁶, C. D. Alonso⁶
¹Massachussetts General Hospital, Boston, MA, ²Johns Hopkins Medical Center, Baltimore, MD, ³Ochsner Medical Center, New Orleans, LA, ⁴Univ. of Colorado, Aurora, CO, ⁵Yale, New Haven, CT, ⁶Beth Israel Deaconess Medical Center, Boston, MA
*Purpose: Transplantation of HIV+ individuals has become more common over the past decade with increasing data supporting good outcomes. Questions remain regarding the impact of…
2021 American Transplant Congress
Kidney Donor Risk Index: Significance as a Predictor of Kidney Transplant Outcomes Beyond Allograft Survival, Analysis of 18 Adjusted Regression Models Involving Adult Deceased Donor Kidney Recipients
A. Santos, E. Bueno, M. A. Leghrouz
University of Florida, Gainesville, FL
*Purpose: We aimed to study the role of kidney donor recipient index (KDRI) as a predictor for multiple transplant-related outcomes in adult deceased-donor (DD) kidney…
2021 American Transplant Congress
Renal Preservation with Belatacept-Based versus Everolimus-Based Immunosuppression in Lung Transplant Recipients
E. Sartain¹, K. Schoeppler¹, B. Crowther¹, J. Smith², A. Gray²
¹University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, ²Department of Medicine, Division of Pulmonary Sciences and Critical Care, University of Colorado, Denver, CO
*Purpose: Renal dysfunction is one of the most common long-term complications among lung transplant recipients (LTRs). Calcineurin-inhibitor (CNI) nephrotoxicity is a recognized contributor to renal…
2021 American Transplant Congress
Non-Invasive Measurement of Transplant Kidney Fibrosis Using Photoacoustic Imaging
E. Hysi¹, X. He¹, A. Krizova¹, M. Ordon¹, K. T. Pace¹, M. Farcas¹, M. C. Kolios², D. A. Yuen¹
¹St. Michael's Hospital, Toronto, ON, Canada, ²Ryerson University, Toronto, ON, Canada
*Purpose: The presence of donor kidney fibrosis adversely impacts transplant outcome. Biopsy remains the only method that can assess fibrosis, despite being subjected to sampling…