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American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Outcomes in Standard vs. Extended Use of Thymoglobulin as Induction Therapy in Kidney Transplant Recipients

    N. M. Sifontis1, A. Coleman1, D. Tang1, K. Lau2, S. Karhadkar2, A. DiCarlo2, A. Diamond2

    1Temple University School of Pharmacy, Philadelphia, PA, 2Temple University Health System, Philadelphia, PA

    *Purpose: Thymoglobulin induction along with modern maintenance immunosuppression has been found to have a significant reduction in acute rejection in kidney transplantation. The recommended duration…
  • 2021 American Transplant Congress

    Obesity Impacts Acute Rejection but Not Allograft Function Improvement in the Setting of Belatacept Conversion

    D. Pierce, J. Benken, P. West-Thielke, I. Tzvetanov, E. Benedetti, A. Lichvar

    University of Illinois at Chicago, Chicago, IL

    *Purpose: There is limited data regarding belatacept conversion in obese patients as an alternative to calcineurin inhibitor (CNI) immunosuppression. Pharmacokinetic (PK) data suggests increasing clearance…
  • 2021 American Transplant Congress

    Graft Volume Changed in the First Year After Living Donor Kidney Transplantation

    M. Abou Zeinab, M. Eltemamy, Y. Lin, K. Sasaki, V. Krishnamurthi, Z. Zaky, A. Wee, J. Kaouk

    Cleveland Clinic, Cleveland, OH

    *Purpose: Pre-donation total kidney volume was shown to correlate with graft outcomes and long-term graft survival. However, only a few studies have studied the changes…
  • 2021 American Transplant Congress

    Clinical Outcomes of Living Kidney Transplantation from Elderly Spousal Donors

    Y. Miyauchi, T. Noda, N. Miura, T. Kikugawa, T. Saika

    Ehime University, Toon, Japan

    *Purpose: In Japan, the spousal kidney transplantation accounts for approximately 40% out of whole living kidney transplantation. In addition, about half of whole living donors…
  • 2021 American Transplant Congress

    Kidney Transplantation from Marginal Donors: An Increased Risk of Urinary Complication. Study from 10279 Patients

    B. Mesnard1, M. Leroy2, J. Hunter3, D. Kervella1, M. Timsit4, L. Badet5, P. Glemain1, E. Morelon5, F. Buron5, M. Le Quintrec-Donnette6, V. Pernin6, M. Ladriere7, S. Girerd7, C. Legendre4, A. Sicard8, L. Albano8, S. De Vergie1, C. Kerleau1, T. Prudhomme9, J. Rigaud1, D. Cantarovich1, G. Blanchot1, G. Karam1, M. Giral1, S. Ville1, J. Branchereau1

    1Department of Urology, Chu Nantes, Nantes Université, ITUN, Nantes, France, Nantes, France, 2Department of Urology, Chu Nantes, Nantes Université, France, Nantes, France, 3Department of Urology, Nuffield Department of Surgical Science ,Oxford, Oxford, United Kingdom, 4Service de transplantation rénale, Hôpital Necker AP-HP, Paris, France, 5Service de transplantation, néphrologie et immunologie clinique, Hôpital Edouard Herriot, Hospices de Lyon, Lyon, France, 6Service de néphrologie-soins intensifs-dialyse et transplantation, Hôpital Lapeyronie, Montpellier, France, 7Service de transplantation rénale, CHU Brabois, Nancy, France, 8Service de néphrologie, Hôpital Pasteur, Nice, France, 9Service urologie, andrologie et transplantation rénale, Hôpital Rangeuil, CHU de Toulouse, Toulouse, France

    *Purpose: Due to the increasing need of kidneys suitable for transplantation, we have expanded the donor population to include marginal donors (Extended criteria donor, controlled…
  • 2021 American Transplant Congress

    Impact of Once-Daily Extended-Release Tacrolimus Intrapatient Variability in Stable Adolescent and Young Adult Renal Transplant Recipients – 3 Year Results

    M. M. Chandran1, E. Blanchette1, J. Goebel2, M. Bock1

    1Children's Hospital Colorado, Denver, CO, 2Helen DeVos Children’s Hospital, Grand Rapids, MI

    *Purpose: Successful renal transplantation requires complex medication regimens that rely heavily on strict adherence to be effective. Variability in immunosuppression exposure, specifically tacrolimus, is associated…
  • 2021 American Transplant Congress

    En Bloc Kidney Transplantation from Pediatrics Weighing Less Than 5 Kg: Single Center Analysis of 31 Cases

    Z. Wang1, X. Zeng2, Q. Xia2, J. Peng2, H. Xiao2, J. Liu2, H. Li2

    1Urology, Huazhong University of Science and Technology, Union Hospital, Wuhan, China, 2Urology, Union Hospital, Wuhan, China

    *Purpose: Very low bodyweight pediatrics are rarely chosen as donors because of potential higher risk for complications such as early allograft thrombosis, and possible latter…
  • 2021 American Transplant Congress

    Comparing Bortezomib Protocol versus IVIG/Rituximab in the Treatment of Antibody Mediated Rejection (AMR) in Kidney Transplantation

    V. M. Lowery1, A. Centeno1, T. Harrison1, P. Cabrera1, A. Mattiazzi2

    1Pharmacy, Jackson Memorial Hospital/Miami Transplant Institute, Miami, FL, 2Nephrology & Hypertension, Miami Transplant Institute, Jackson Memorial Hospital/Miami Transplant Institute, Miami, FL

    *Purpose: To compare outcomes of historical treatment of AMR [PLEX + IVIG + Rituximab] with addition of bortezomib, along with characterizing safety parameters aimed at…
  • 2021 American Transplant Congress

    De Novo Atypical Hemolytic Uremic Syndrome (aHUS) in Kidney Transplant Recipients from the Same Donor: Possible Role of Two Genetic Hits

    C. Crane1, J. Sherbotie2, S. Anand3

    1University of California at San Diego, San Diego, CA, 2University of Utah School of Medicine, Salt Lake City, UT, 3Nephrology Associates of Utah, Salt Lake City, UT

    *Purpose: Thrombotic microangiopathy (TMA) is an uncommon and potentially serious complication of kidney transplantation. Atypical hemolytic uremic syndrome (aHUS) is a type of TMA most…
  • 2021 American Transplant Congress

    Intermediate Outcomes Following Early Inflammatory Changes on Surveillance Biopsies

    I. Melgarejo1, V. Viswanathan2, A. Sharma1, P. Sood1, C. Puttarajappa1, N. Shah1, M. Molinari1, A. Tevar1, C. Wu1, S. Hariharan1, R. Mehta1

    1Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, 2Department of Renal-electrolyte, University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: The implications on early inflammatory changes on surveillance biopsies on intermediate and long-term outcomes is unclear.*Methods: Of the 1000 kidney transplant (live donor and…
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