Am J Transplant, Volume 21, Suppl 3 Archives - Page 17 of 139 - ATC Abstracts

2021 American Transplant Congress
Single-cell Rna Sequencing of Latent Murine Cytomegalovirus Infected Lung Transplants
L. A. VanOsdol¹, S. Han¹, M. Kandpul², J. J. Wang¹, L. Qiu³, Z. J. Zhang¹
¹Comprehensive Transplant Center, Northwestern University, Chicago, IL, ²Department of Surgery, Northwestern University, Chicago, IL, ³School of Medicine, University of California, San Fransisco, San Fransisco, CA
*Purpose: Analyze the transcriptomics of mouse lung cells with and without latent infection of cytomegalovirus (CMV) before and after transplantation and identify key cell types…
2021 American Transplant Congress
Biomarkers of Kidney Injury and Repair in Expanded-Criteria Deceased Donor Kidney Transplant Recipients: A Prospective Study
A. Al Jurdi¹, O. Efe¹, B. Aoyama², M. Lima², H. Silva², I. Schmidt³, S. Waikar³, V. Sabbisetti⁴, L. V. Riella¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, ²Escola Paulista de Medicina, UNIFESP, São Paulo, Brazil, ³Boston Medical Center, Boston, MA, ⁴Brigham and Women’s Hospital, Boston, MA
*Purpose: Expanded-criteria donor (ECD) kidney transplants are at higher risk of kidney injury. Biomarkers that better predict short and long-term outcomes in ECD kidney transplant…
2021 American Transplant Congress
The Impact of Maintenance Immunosuppression Withdrawal on Sensitization Status After Renal Graft Failure
R. Hod Dvorai, A. Almonte, C. Hubbell, M. Laftavi, R. Shahbazov, R. Saidi, O. Pankewycz, J. Leggat, M. Hanlon, B. Gallay
SUNY Upstate Medical University, Syracuse, NY
*Purpose: Maintaining immunosuppression (IS) following failed renal transplant may lead to increased risk for infections and malignancies; on the other hand, withdrawal can lead to…
2021 American Transplant Congress
Kidney Graft Biopsy for Indication Proteinuria: Finding, and Outcomes
S. Parajuli, K. Swanson, J. Alstott, F. Aziz, N. Garg, W. Zhong, A. Djamali, D. Mandelbrot
University of Wisconsin, Madison, WI
*Purpose: Proteinuria is common in kidney transplant recipients (KTRs), and is associated with an increased risk of graft failure. A rise in serum creatinine (SCr)…
2021 American Transplant Congress
Comparison of Next Generation Sequencing Donor-derived Cell Free DNA Assay Utilizing Whole Genome Sequencing
N. Singh¹, M. S. Naseer¹, D. Aultman², H. Shokouh-Amiri², G. Zibari²
¹Transplant, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA, ²Advanced Surgery, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA
*Purpose: Circulating donor-derived cell free DNA (dd-cfDNA) is a non-invasive biomarker of kidney allograft injury with a high negative predictive value for ruling out acute…
2021 American Transplant Congress
Long-Term Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Living Donor Renal Transplant Recipients
J. Leventhal¹, J. Galvin², J. Mathew¹, L. Gallon¹, D. Belshe¹, M. Gibson¹, K. Ravindra³, M. Horwitz³, S. Ildstad⁴
¹Northwestern University, Comprehensive Transplant Center, Chicago, IL, ²Northwestern University, Chicago, IL, ³Duke Medical Center, Durham, NC, ⁴University of Louisville, Llouisville, KY
*Purpose: 37 subjects were transplanted in a phase 2 protocol based upon tolerogenic CD8+/TCR-facilitating cells (FCR001) to induce tolerance in recipients of living donor renal…
2021 American Transplant Congress
Intravenous Immunoglobulin in Heart Transplant Recipients with Hypogammaglobulinemia and Infection
J. Hoang, D. Nguyen, E. Graviss, M. Moaddab, A. Guha, J. Krisl
Houston Methodist Hospital, Houston, TX
*Purpose: Hypogammaglobulinemia (HGG) is a complication of solid organ transplantation which has been associated with increased risk of infections. HGG is commonly defined as a…
2021 American Transplant Congress
Cryptococcosis in Renal Transplant Recipients —An Analysis of United States Renal Data System Data
M. E. Cervera-Hernandez, H. A. Yoon, L. Pirofski, V. Hemmige
Montefiore Medical Center, Bronx, NY
*Purpose: Solid organ transplant recipients are at increased risk for cryptococcosis, which is known to decrease their survival. Adherence to recommended management strategies and outcomes…
2021 American Transplant Congress
Breakthrough Cytomegalovirus DNAemia in High vs Intermediate Risk Heart Transplant Recipients
G. Huang¹, O. E. Beaird¹, M. Davis², M. Carlson¹, S. Chang¹, P. Gaynor¹, A. Fan², M. Deng³, A. Multani¹, A. Nsair³, J. Schaenman¹
¹Infectious Diseases, UCLA, Los Angeles, CA, ²Pharmacy, UCLA, Los Angeles, CA, ³Cardiology, UCLA, Los Angeles, CA
*Purpose: Cytomegalovirus (CMV) is one of the most common infections after transplantation and continues to cause significant morbidity and mortality despite prophylaxis and screening strategies.…
2021 American Transplant Congress
Covid vs Non Covid Pneumonia in Kidney Transplant Recipients
R. Prashar, N. Khoury, P. Shrivastava, S. Yeddula, T. Kitajima, E. Ulrich, M. Ramesh, A. Patel, S. Nagai, M. Samaniego-Picota
Henry Ford Hospital, Detroit, MI
*Purpose: Compare clinical characteristics and outcomes in kidney transplant recipients (KTRs) hospitalized with COVID vs Non COVID Pneumonia.*Methods: This is a retrospective case‐control study examining…