2021 American Transplant Congress
Pre- Kidney Donation Pregnancy Complications and Long-Term Outcomes
*Purpose: In general, hypertension (HTN), proteinuria, or diabetes (DM) are exclusion criteria for living kidney donation in young candidates. Exceptions are made for conditions only…2021 American Transplant Congress
A Cost Benefit Analysis of Different Minimal Access Donor Nephrectomy Techniques Performed at a Busy Transplant Centre
*Purpose: We performed the cost-benefit analyses comparing Total Laparoscopic Retroperitoneoscopic donor nephrectomy (TLTLRPDN) versus Hand-assisted laparoscopic donor nephrectomy (HALDN) operations performed at our centre since…2021 American Transplant Congress
Exosomal DAMP Proteins Released During Islet Isolation Affects TPIAT Outcomes
Hume Lee Islet Cell Transplantation Lab, Department of Surgery, VCU Health, Richmond, VA
*Purpose: Isolation of islets cause significant stress that results in the release of immunogenic factors called damage-associated molecular patterns (DAMPs) which can induce inflammatory signaling…2021 American Transplant Congress
Pre-transplant Lower Urinary Tract Dysfunction in Men is a Risk Factor for Adverse Outcomes Following Renal Transplantation
*Purpose: The expanding age criteria for candidacy for renal transplantation, in conjunction with prolonged waiting time for deceased donor kidneys has created new challenges for…2021 American Transplant Congress
Single Day Centralized Approach in Kidney Transplant Workup – Lessons Learned from 2 Centers
Tulane Abdominal Transplant Institute, New Orleans, LA
*Purpose: Time from transplant evaluation to UNOS listing is unaccounted towards wait-list time in pre-dialysis patients and hence longer evaluation to listing times can prolong…2021 American Transplant Congress
Belatacept and Rapamycin Maintenance Immunosuppression in a Sensitized Nonhuman Primate Kidney Allotransplantation Model
*Purpose: Desensitization with costimulation blockade and proteasome inhibition prior to kidney transplantation prevents early antibody-mediated rejection (AMR) and prolongs graft survival in highly sensitized nonhuman…2021 American Transplant Congress
Antibodies to Hla Molecules Lead to Induction and Release of Circulating Exosomes with Lung Self-Antigens
St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: Antibodies (Abs) to human leukocyte antigen (HLA) (anti-HLA) can injure allograft by complement-dependent/independent mechanisms. Crosslinking of HLA-class I with Abs associate with integrin β4…2021 American Transplant Congress
First Full Reversal of Diabetes in Non-human Primates (nhp) with Stem Cell Derived Islet-like-clusters (sc-ilcs)
*Purpose: Deceased donor allo-islet transplants (Tx) have demonstrated the ability of cell-based therapy to fully reverse T1D, however, an inadequate donor supply and frequent need…2021 American Transplant Congress
Portal Hypertension Abrogates Trail Expression of Liver Resident Nk Cells via Il-33
Hiroshima Uni., Hiroshima, Japan
*Purpose: Portal vein hypertension (PHT) is associated with poor prognosis, risk factors for small graft syndrome, bloodstream infection, and acute rejection after living donor liver…2021 American Transplant Congress
K562 Cells Expressing HLA-A2 Stimulate Alloreactive CD8+ T Cells
Emory Transplant Center, Emory University, Atlanta, GA
*Purpose: T cell-mediated rejection is a significant factor that leads to graft damage and loss in transplant recipients. Due to the complexity of the TCR:pMHC…
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