Am J Transplant, Volume 21, Suppl 3 Archives - Page 129 of 139 - ATC Abstracts

2021 American Transplant Congress
Prediction of Renal Allograft Tolerance by Machine Learning
Q. Fu¹, K. Deng², H. Yang¹, S. Deng¹, J. F. Markmann²
¹Organ Transplantation Center, Sichuan Provincial People's Hospital, University of Electronic Sciences and Technology of China, Chengdu, China, ²Center for Transplantation Sciences, MGH, Boston, MA
*Purpose: An ideal goal of transplantation is to withdraw or minimize immunosuppressants via the induction of tolerance to overcome drug toxicity, prolong allograft survival, and…
2021 American Transplant Congress
Depressive Symptoms and Listing for Kidney Transplantation
X. Chen, N. Chu, P. Sharma Basyal, W. Vihokrut, D. Crews, D. Brennan, S. Andrews, T. Vannorsdall, D. Segev, M. McAdams DeMarco
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Among patients with kidney failure, depressive symptoms are common and may be a barrier to completing the complex process of kidney transplantation (KT) evaluation…
2021 American Transplant Congress
Alpha 1-antitrypsin Reduces Cytokine Elaboration in a Xenogeneic Lung Transplantation Model
L. Burdorf¹, C. Laird², T. Zhang², M. R. Connolly¹, Z. Habibabady¹, S. Pratts¹, S. Miura¹, F. Pollok¹, W. Eyestone³, C. J. Phelps³, D. L. Ayares³, A. M. Azimzadeh¹, R. N. Pierson III¹
¹Surgery, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Surgery, University of Maryland, Baltimore, MD, ³Revivicor, Blacksburg, VA
*Purpose: Novel gene editing techniques have facilitated the generation of donor pigs with multiple genetic modifications, used for xenolung transplantation. Several rejection pathways, including antibody…
2021 American Transplant Congress
Outcomes of Kidney Transplantation from Hepatitis C Virus (HCV) Infected Donors Stratified by Recipient HCV Serostatus: A Mate Kidney Analysis
K. K. Sureshkumar¹, B. Chopra¹, R. L. McGill²
¹Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA, ²Nephrology, University of Chicago, Chicago, IL
*Purpose: Kidneys from donors infected with hepatitis C virus (HCV) are increasingly used for transplantation into HCV positive (+) recipients historically and into HCV negative…
2021 American Transplant Congress
Primary Uretero-ureterostomy in Renal Transplantation
H. Shokouh-Amiri¹, M. S. Naseer¹, D. Aultman¹, R. McMillan¹, S. Tandukar², F. T. Siskron³, N. Singh², G. Zibari¹
¹Advanced Surgery, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA, ²Transplant Nephrology, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA, ³Urology, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA
*Purpose: Uretero-neocystostomy (UN) is routinely performed in renal transplantation. Few studies of primary uretero-ureterostomy (UU) have been reported, showing its safety and feasibility. If the…
2021 American Transplant Congress
Kidney Programs Can Filter Off a Majority of Their Unwanted Organ Offers without Harming Transplant Volumes
A. Toll, H. McGehee, R. McTier, D. Stewart
Research, United Network for Organ Sharing, Richmond, VA
*Purpose: Evaluate if multifactorial filters can reduce unwanted kidney offers to centers, thereby reducing administrative burden and getting to the accepting candidate quicker.*Methods: 34 centers…
2021 American Transplant Congress
Long Term Survival After Liver Transplantation for Advanced, Unresectable Intrahepatic Cholangiocarcinoma
R. R. McMillan¹, S. Kodali¹, M. Javle², A. Saharia¹, C. M. Mobley¹, M. J. Hobeika¹, A. Shetty¹, D. W. Victor¹, R. McFadden¹, M. Abdelrahim¹, K. Heyne¹, A. O. Gaber¹, R. M. Ghobrial¹
¹Houston Methodist Hospital, Houston, TX, ²MD Anderson Cancer Center, Houston, TX
*Purpose: Intrahepatic cholangiocarcinoma (ICCA) has traditionally been considered a contraindication to liver transplantation (LT). We previously reported a case series of six patients with large,…
2021 American Transplant Congress
Clinical Impact of Transplant Pharmacists on the Care of Solid Organ Transplant Recipients
I. Shah¹, J. Au¹, A. Diamond¹, N. Sifontis², C. Ruggia-Check¹
¹Temple University Hospital, Philadelphia, PA, ²Temple School of Pharmacy, Philadelphia, PA
*Purpose: The United Network for Organ Sharing (UNOS) and Centers for Medicare and Medicaid Services (CMS) requires transplant centers to document the participation of a…
2021 American Transplant Congress
Belatacept-Resistant T Cells are Activated by IFNα-IRF7 Pathway
F. Herr, K. Bargiel, A. Vernochet, A. Durrbach
UMR1186, Villejuif, France
*Purpose: Second signal of activation play an important role in activation of T lymphocytes. Their control by checkpoint inhibitor is efficient in auto-immune disease and…
2021 American Transplant Congress
Donor-specific Regulatory B Cells Prolong Skin Graft Survival by Preventing the Proliferation of Donor-specific CD4 Helper but Not of CD8 Effector T Cells
G. Huai¹, K. Lee², K. Deng², Q. Fu¹, C. G. Rickert², S. Deng¹, C. LeGuern², J. F. Markmann²
¹Department of Organ Transplantation Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China, ²Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA
*Purpose: TLR-Bregs were defined by our group as B cells generated in vitro. They have demonstrated the ability to inhibit CD4 T cell proliferation. Since…