ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Centre Variation in Emergency Hospital Readmissions Following Renal Transplantation in England

    J. Peracha1, D. Pitcher1, R. Steenkamp1, J. Medcalf2, G. Lipkin3, D. Nitsch4, W. McKane5

    1UK Renal Registry, Bristol, United Kingdom, 2John Walls Renal Unit, Leicester General Hospital, Leicester, United Kingdom, 3University Hospitals Birmingham, Birmingham, United Kingdom, 4London School of Hygiene and Trpoical Medicine, London, United Kingdom, 5Sheffield Kidney Institute, Northern General Hospital, Sheffield, United Kingdom

    *Purpose: Emergency hospital readmissions (EHR) following surgery are associated with significant patient distress, morbidity and costs to healthcare providers. In this study we aim to…
  • 2021 American Transplant Congress

    Feasibility of Normothermic Ex Vivo Kidney Perfusion for Human Kidney Transplantation: First North American Results

    L. I. Mazilescu1, P. Urbanellis1, J. S. Kim1, A. Konvalinka1, T. W. Reichman1, L. A. Robinson2, A. Ghanekar1, M. Selzner1

    1Ajmera Transplant Program, Toronto General Hospital, Toronto, ON, Canada, 2Department of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada

    *Purpose: Normothermic ex vivo kidney perfusion is a novel preservation technique with promising results in porcine models and initial clinical results in one European center.…
  • 2021 American Transplant Congress

    Targeting Calcineurin/nfatc2 Signaling to Restore Pancreatic Beta-cell Function in Islet Transplantation

    C. Darden1, J. Mattke1, S. Vasu1, K. Kumano1, Y. Liu1, B. Naziruddin2, M. C. Lawrence1

    1Baylor University Medical Ctr, Dallas, TX, 2Baylor University Medical Ctr, Allen, TX

    *Purpose: Pancreatic beta cells dedifferentiate upon exposure to metabolic and inflammatory stress characterized by loss of beta-cell identity genes, expression of beta-cell disallowed genes, and…
  • 2021 American Transplant Congress

    CD56dimCD16bright NK Cells from Kidney Transplant Recipients with Antibody-mediated Rejection Display Increased Proliferation, Type-1 Activation and Cytotoxic Profile

    E. Bailly1, C. Macedo1, K. Louis1, B. Ramaswami1, M. Lucas1, C. Bentlejewski1, P. Randhawa1, A. Zeevi1, C. Lefaucheur2, D. Metes1

    1Department of Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, 2INSERM UMR-S976. Endothelium, Inflammation & Alloreactivity, Université de Paris, Paris, France

    *Purpose: CD56dimCD16bright NK cells are highly potent for cytotoxicity through cell-mediated cytotoxicity (CMC), antibody-dependent cell-mediated cytotoxicity (ADCC) and INF-γ production. The contribution of NK cells…
  • 2021 American Transplant Congress

    Nutritional Inadequacy is an Independent Predictor of Sepsis Post-liver Transplantation

    J. V. Nolte Fong, M. Elshawwaf, L. W. Moore, E. A. Graviss, D. T. Nguyen, R. Angell, A. Uosef, T. Hirase, C. M. Mobley, R. Ghobrial

    Houston Methodist Hospital, Houston, TX

    *Purpose: Malnutrition is universally prevalent in liver transplant (LT) recipients in the perioperative setting. Malnutrition contributes to post-LT complications, such as sepsis. We aimed to…
  • 2021 American Transplant Congress

    Cross-Circulation for Extracorporeal Liver Support in a Swine Model

    W. K. Wu1, A. Tumen1, J. W. Stokes2, R. Ukita2, A. E. Hozain3, C. R. Flynn2, M. J. Lee3, J. R. Talackine2, N. L. Cardwell2, J. A. Reimer3, M. Pinezich3, C. Benson2, G. Vunjak-Novakovic3, S. P. Alexopoulos2, M. Bacchetta2

    1co-first authors, Vanderbilt University Medical Center, Nashville, TN, 2Vanderbilt University Medical Center, Nashville, TN, 3Columbia University Medical Center, New York, NY

    *Purpose: Although machine perfusion has gained momentum as an organ preservation strategy in liver transplantation, significant organ shortages and waitlist mortality persist, highlighting unmet needs…
  • 2021 American Transplant Congress

    CT-measured Cortical Volume Ratio is an Alternative to Nuclear Medicine Split Scan Ratio Among Living Kidney Donors

    J. Montgomery, C. Brown, A. Zondlak, K. Walsh, J. Kozlowski, A. Pinsky, E. Herriman, J. Sussman, Y. Lu, E. Stein, P. Shankar, R. Sung, K. Woodside

    Michigan Medicine, Ann Arbor, MI

    *Purpose: The 125I-iothalamate clearance and 99mTc-DTPA split scan nuclear medicine studies are used among living kidney donor candidates to determine mGFR and split-scan ratio (SSR).…
  • 2021 American Transplant Congress

    Noninferiority Outcomes Among Undocumented Immigrant Kidney Transplant Recipients in California

    H. Ichii1, N. Eguchi1, E. Tantisattamo2, U. Reddy2, A. Ferrey2, D. Dafoe1

    1Surgery, University of California Irvine, Orange, CA, 2Medicine, University of California Irvine, Orange, CA

    *Purpose: There are over 2 million undocumented immigrants (UI) in California, where currently, all individuals regardless of immigration status have equal access to kidney transplant(KT).…
  • 2021 American Transplant Congress

    Managing the Costs of Routine Follow-up Care After Living Kidney Donation: A Survey of Contemporary Experience, Practice & Challenges

    K. Lentine1, G. McNatt2, R. Howey3, C. Thomas2, R. Hays4, U. Lebron-Banks5, S. Ainapurapu1, A. Tietjen6

    1Saint Louis University, Saint Louis, MO, 2Univ. Iowa, Iowa City, IA, 3Toyon Associates, Concord, CA, 4Univ. Wisconsin, Madison, WI, 5New York-Presbyterian Hosp., New York, NY, 6St. Barnabas, Livingston, NJ

    *Purpose: Organ Procurement and Transplantation Network (OPTN) Policy mandates that living kidney donor (LKD) programs collect and report clinical and laboratory follow-up information for living…
  • 2021 American Transplant Congress

    Iatrogenic Sodium Exposure in Hospitalized Patients with Liver Disease

    P. Klem1, R. Mbangu Kot Mbau2, B. Crowther1, V. Lewis1, S. Lin1, E. Patrick3, A. Nadrash1, K. Schoeppler1, I. Kim1

    1Pharmacy, University of Colorado Hospital, Aurora, CO, 2Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, 3Transplant Services, University of Colorado Hospital, Aurora, CO

    *Purpose: Numerous medications administered in the hospital setting may contain hidden/additional amounts of sodium in the drug itself and via intravenous (IV) diluents or admixtures.…
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