ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    White, Older Men Are Less Affected by the Changes of the Covid-19 Pandemic

    R. J. Berkowitz, A. Daud, S. Brietigam, T. S. Taylor, J. Carter, M. A. Callegari, B. Borja-Cacho, J. C. Caicedo, D. Simpson, D. P. Ladner

    Surgery, Northwestern Medicine, Chicago, IL

    *Purpose: This study explores quality of life and lifestyle changes due to the COVID-19 pandemic among pre- and post- liver (LT) and kidney (KT) transplant…
  • 2021 American Transplant Congress

    Characterisation of Distinct Graft Infiltrates Following Cellular Therapy in Kidney Transplant Recipients

    M. O. Brook1, P. N. Harden2, I. Roberts2, W. R. Mulley3, J. Hester1, M. E. Reinders4, F. Issa1

    1Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, 2Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom, 3Department of Nephrology, Monash Medical Centre, Melbourne, Australia, 4Division of Nephrology and Transplant Center, Leiden University Medical Center, Leiden, Netherlands

    *Purpose: Cellular therapy is an emerging treatment in the field of clinical transplantation with the potential to improve both short and long-term transplant outcomes. We…
  • 2021 American Transplant Congress

    The Association Between Environmental Determinants and High KDRI Organ Offer Acceptance Ratios

    A. M. Placona, C. Martinez, M. Stuart

    United Network for Organ Sharing, Henrico, VA

    *Purpose: Increasing the number of transplants could be realized by increasing high KDRI organ utilization. While the impact of transplant center (TXC) aggressiveness and competition…
  • 2021 American Transplant Congress

    Allograft Discard Risk Index for Heart Transplantation

    R. M. Reul1, A. A. Saleem1, C. N. Keller1, T. H. Malik1, J. A. Goss2, A. A. Rana2

    1Office of Student Affairs, Baylor College of Medicine, Houston, TX, 2Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX

    *Purpose: The number of patients awaiting heart transplantation (HTx) substantially exceeds the number of donor hearts transplanted each year, yet nearly 70% of consented donor…
  • 2021 American Transplant Congress

    Characterizing Kidney Transplant Recipients with SARS-CoV-2: An Academic Single Center Experience

    S. Nahi, A. Shetty, S. Tanna, J. Leventhal

    Northwestern University, Chicago, IL

    *Purpose: Kidney transplant (KTx) recipients are a unique cohort in regard to SARS-CoV-2 susceptibility and clinical course, owing to their immunosuppressed state and propensity for…
  • 2021 American Transplant Congress

    Drivers of Graft Failure in Pediatric Kidney Transplant Change Over Time

    E. Benz1, D. Schaubel2, S. Amaral1

    1Children's Hospital of Philadelphia, Philadelphia, PA, 2Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA

    *Purpose: Short-term pediatric kidney transplant outcomes have improved over time with advanced surgical techniques and better immunosuppression, but long-term graft outcomes remain suboptimal - concerning…
  • 2021 American Transplant Congress

    Liver Kinase B1 Knockdown Induces Platelet-Derived Growth Factor Receptor B Expression in Human Airway Epithelial Cells: A Potential Mechanism for Development of Fibrosis Leading to Chronic Lung Allograft Dysfunction

    M. Rahman, J. Lee, R. Ravichandran, T. Fleming, M. Smith, R. Bremner, T. Mohanakumar

    St. Joseph’s Hospital and Medical Center, Phoenix, AZ

    *Purpose: The platelet-derived growth factor and its receptor (PDGFRb) signaling pathway can be activated by epithelial mesenchymal transition which facilitates fibrosis. It is not known…
  • 2021 American Transplant Congress

    Centers Avoided 67% of Kidney Offers by Participating in the OPTN’s Multifactorial Offer Filter Pilot Project

    A. Toll, H. McGehee, D. Stewart, R. McTier

    Research, United Network for Organ Sharing, Richmond, VA

    *Purpose: Evaluate if multifactorial filters can reduce unwanted kidney offers to centers, thereby reducing administrative burden and getting to the accepting candidate quicker.*Methods: 40 centers…
  • 2021 American Transplant Congress

    Changes to Adult Heart Allocation Improve Candidate Stratification

    K. Bradbrook1, K. Lindblad1, R. R. Goff1, R. Daly2, S. Hall3

    1Research, United Network for Organ Sharing, Richmond, VA, 2Mayo Clinic, Rochester, MN, 3Baylor University Medical Center, Dallas, TX

    *Purpose: Historically, heart allocation has been driven by waitlist (WL) mortality rather than post-transplant survival. On 10/18/2018 the Organ Procurement and Transplantation Network (OPTN) implemented…
  • 2021 American Transplant Congress

    COVID-19 Potential Donor Derived Transmission Events Investigations: Early DTAC Experience

    R. La Hoz, A. Agarwal, S. Aslam, K. Dunn, J. Goldman, D. Levine, C. Marboe, G. F. Marklin, S. M. Pouch, M. Rana, R. Razonable, H. L. Stevenson, H. Te, A. E. Woolley, M. Michaels, L. Danziger-Isakov

    OPTN DTAC, Richmond, VA

    *Purpose: US Solid organ transplantation rates significantly decreased during the initial wave of the COVID-19 pandemic. The concern for potential donor derived COVID-19 was one…
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