Am J Transplant, Volume 21, Suppl 3 Archives - Page 113 of 139 - ATC Abstracts

2021 American Transplant Congress
Nanoparticle Mediated Drug Delivery for Lung Transplantation
P. M. Patel¹, S. Jung², C. L. Miller¹, J. M. O¹, T. Costa¹, A. Dehnadi¹, I. Hanekamp¹, X. F. Li², L. Jiang², H. Ichimura², A. Azimzadeh¹, J. C. Madsen³, R. Abdi²
¹Surgery, Center for Transplantation Sciences, Massachusetts General Hospital/Harvard Medical School, Boston, MA, ²Medicine, Transplant Research Center, Brigham and Women's Hospital, Boston, MA, ³Surgery, Center for Transplantation Sciences, Division of Cardiac Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA
*Purpose: Severe primary graft dysfunction (PGD) affects 30% of lung transplant patients. Pulmonary alveolar macrophages play a significant role in lung PGD, but systemic immunotherapy…
2021 American Transplant Congress
Prospective Intensive Monitoring for Anamnestic DSA Responses Allows Near Elimination of Early Clinical AMR
M. McGowan¹, A. Bickenbach¹, A. R. Shields², R. R. Alloway¹, P. Brailey¹, E. Portwood¹, C. Alquist¹, A. Christianson¹, B. Abu Jawdeh¹, M. Cuffy¹, J. Kremer², S. Bumb¹, A. Govil¹, M. Anand¹, T. Kaur¹, E. S. Woodle¹
¹U Cincinnati, Cincinnati, OH, ²Christ Hospital, Cincinnati, OH
*Purpose: Anamnestic donor specific antibody (aDSA) responses can result in severe, graft threatening antibody-mediated rejection (AMR). We hypothesized that intensive DSA monitoring (IDM) for aDSA…
2021 American Transplant Congress
High and Low Frequency Domino Liver Transplantation Centers Demonstrate Similar Outcomes
J. Panichella, H. Resweber, H. Curtis, K. Nguyen, A. Di Carlo, S. Karhadkar
Temple University School of Medicine, Philadelphia, PA
*Purpose: For patients with transthyretin (TTR) Amyloidosis, the only disease modifying treatment is an orthotopic liver transplant. However, because of the nature of this disease,…
2021 American Transplant Congress
Cellular Landscape of Steatotic Livers Revealed by Single-nuclei Rna Sequencing
C. Kuscu¹, C. Kuscu¹, A. Shetty², E. Bardhi³, T. Rousselle⁴, J. Eason¹, M. Sraj⁵, D. Maluf⁶, V. Mas⁴
¹Surgery, James D Eason Transplant Institute, Memphis, TN, ²University of Maryland, Institute for Genome Sciences, Baltimore, MD, ³Program in Transplantation - University of Maryland, Baltimore, MD, ⁴Surgery, Division of Surgical Science, Baltimore, MD, ⁵Surgery, University of Maryland, Baltimore, MD, ⁶Surgery, Program in Transplantation - University of Maryland, Baltimore, MD
*Purpose: Hepatic IRI represents a barrier to the use of available organs for transplant, particularly fatty livers. We aimed to discern the cellular subsets and…
2021 American Transplant Congress
Launching a National Living Donor Registry
J. E. Milton¹, M. Cooper², B. Hippen³
¹Transplant Center, University of Texas Health San Antonio, San Antonio, TX, ²MedStar Georgetown Transplant Institute, Washington, Colombia, ³Metrolina Nephrology Associates, PA, Charlotte, NC
*Purpose: The National Donate Life Living Donor Registry launching in 2021 will allow 4000 persons a day the opportunity to become a living donor offering…
2021 American Transplant Congress
Frequency and Types of Pharmacist Interventions and Risk Assessments Occurring During the 12-Month Transafe Rx Randomized Controlled Trial
H. M. Gonzales, J. N. Fleming, D. J. Taber
MUSC, Charleston, SC
*Purpose: Clinical pharmacists have unique education and training to identify and mitigate medication (med) safety issues in high-risk populations, such as kidney transplant (KTX). The…
2021 American Transplant Congress
Recipient and Kidney Allograft Outcomes from Hypertensive Live-Donor in the United States
S. Riad¹, S. Jackson², D. Vock³, A. Matas⁴
¹Medicine, University of Minnesota, Minneapolis, MN, ²Complex Care Analytics, M-Health Fairview, Minneapolis, MN, ³School of Public Health, University of Minnesota, Minneapolis, MN, ⁴Surgery, University of Minnesota, Minneapolis, MN
*Purpose: Controlled hypertension in select prospective kidney donors is no longer an exclusion criterion for donation. We examined the association between pre-donation hypertension (HTN) and…
2021 American Transplant Congress
Experiences of Women Trainees in Transplant Surgery
A. E. Gomez-Rexrode¹, D. E. Cassidy¹, M. S. Anderson², J. R. Santos-Parker¹, L. M. McElroy³, S. A. Waits², V. S. Valbuena²
¹University of Michigan Medical School, Ann Arbor, MI, ²Department of Surgery, University of Michigan Health System, Ann Arbor, MI, ³Department of Surgery, Duke University Medical Center, Durham, NC
*Purpose: To assess the unique experiences of women surgical trainees to better understand the recruitment and training strategies needed to ensure meaningful progress toward gender…
2021 American Transplant Congress
Wave of the Future: Expanding Role and Necessity of the Dedicated Procurement Surgeon
C. Strom, B. Cimsit, H. Nelson, F. Delmonico
New England Donor Services, Waltham, MA
*Purpose: To evaluate the quantitative and qualitative benefits of a dedicated procurement surgeon (DPS) across the transplant spectrum, including the DPS technical performance value for…
2021 American Transplant Congress
DAP12 Promotes Liver DC Tolerogenicity by Negative Regulation of the CGAS-STING-IFN I Pathway
Y. Zheng¹, J. Long², N. Ryosuke¹, L. Peng³, F. Peng³, A. Thomson¹
¹Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, ²Department of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, China, ³Department of Kidney Transplantation, The Second Xiangya Hospital of Central South University, Changsha, China
*Purpose: Constitutive expression of comparatively high levels of DNAX-activating protein of 12KDa (DAP12) by liver myeloid dendritic cells (mDCs) has been implicated in their immune…