ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Impact of Covid-19 in Transplant Care: Attitudes, Feeling and Behaviors of Liver, and Kidney Pre and Post Transplant Patients

    J. Ramos-Ayes

    Beth Israel Deaconess Medical Center, Boston, MA

    *Purpose: The SARS-CoV-2(COVID-19) pandemic poses unique challenges for transplant patients, which may impact their attitudes, emotions and behaviors associated with transplant care. This study surveys…
  • 2021 American Transplant Congress

    Impact of Extended Living Donor Criteria on Donor Safety in Living Donor Liver Transplantation

    J. KIM

    Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea, Republic of

    *Purpose: Donor safety is major concern during living donor liver transplantation (LDLT) and most transplant centers accept strict selection criteria although some centers have been…
  • 2021 American Transplant Congress

    The Learning Curve Associated with De Novo Tacrolimus XR Use in a Racially Diverse Kidney Transplant Population

    F. Bartlett, T. Carcella, N. Patel, V. Rohan, D. Taber

    Medical University of South Carolina, Charleston, SC

    *Purpose: Tacrolimus XR (LCP-Tac) was approved for de novo dosing in kidney transplant recipients in 2018. In 2020, our center was challenged with a nationwide…
  • 2021 American Transplant Congress

    MDR-101-MLK-MERCURY Kidney Transplant Tolerance Study Update

    D. Kaufman1, S. Akkina2, M. Stegall3, J. Piper4, A. O. Gaber5, E. Marin6, S. Busque7, D. Alonso8, M. De Vera9, A. Shah10, A. Patel11, K. Chavin12, M. Laftavi13, S. Collette14, E. Stites15, M. Mai16, M. Cooper17, D. Brennan18

    1Surgery, UW, Madison, WI, 2Surgery, Loyola, Chicago, IL, 3Surgery, Mayo, Rochester, MN, 4Surgery, Inova, Fairfax, VA, 5Surgery, Houston Methodist, Houston, TX, 6Nephrology, Yale, New Haven, CT, 7Surgery, Stanford, San Francisco, CA, 8Surgery, Intermountain, Murray, UT, 9Surgery, Loma Linda, Loma Linda, CA, 10Surgery, TJU, Philadelphia, PA, 11Nephrology, St. Barnabas, Livingston, NJ, 12Surgery, UHH, Cincinnati, OH, 13Surgery, Upstate, Syracuse, NY, 14Surgery, CIUSSS, Montreal, ON, Canada, 15Nephrology, UC Denver, Denver, CO, 16Nephrology, Mayo - FL, Jacksonville, FL, 17Surgery, Georgetown, Washington, DC, 18Medeor, San Francisco, CA

    *Purpose: We report interim results of the Phase 3 MERCURY tolerance study, which produces mixed chimerism and ultimately generates operational tolerance allowing for the elimination…
  • 2021 American Transplant Congress

    Late Subclinical Rejection and Borderline Rejection in Kidney Transplant Patients is Associated with Increased Incidence of Subsequent Clinical Rejections

    V. Viswanathan1, I. Melgarejo2, C. Puttarajappa2, P. Sood2, M. Molinari2, S. Hariharan2, C. Wu2, A. Sharma2, N. Shah2, R. Mehta2

    1Department of Medicine, Renal-Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA, 2Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: The outcomes of inflammatory changes noted in late surveillance biopsies (1 year) is unclear.*Methods: Patients transplanted (live donor and deceased donor) at our center…
  • 2021 American Transplant Congress

    Limited Immunogenicity of a Single Dose of Sars-cov-2 Mrna Vaccine in Solid Organ Transplant Recipients

    B. Boyarsky, M. Ou, R. Greenberg, A. Teles, W. Werbel, R. Avery, A. Tobian, A. Massie, D. Segev, J. Garonzik Wang

    Johns Hopkins, Baltimore, MD

    *Purpose: Given substantial challenges with vaccine allocation and evidence for short-term vaccine efficacy after a single dose of SARS-CoV-2 mRNA vaccines in clinical trials, some…
  • 2021 American Transplant Congress

    Successful Induction of Hematopoietic Chimerism by Dual Inhibition of Mcl-1 and Bcl-2 Without Myeloablative Treatments in Nonhuman Primates

    T. Hirose, D. Ma, G. Lassiter, T. Kawai

    Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA

    *Purpose: Induction of hematopoietic chimerism by donor bone marrow transplantation (BMT) is essential for achievement of allograft tolerance in clinical HLA mismatched kidney transplantation, while…
  • 2021 American Transplant Congress

    Clinical Outcomes Associated with Induction Therapy Regimens for Kidney Transplantation in Children: A NAPRTCS and PHIS Collaborative Report

    H. Pizzo1, D. Levy Erez2, N. M. Rodig3, T. Richardson4, M. Somers3

    1Pediatric Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA, 2Nephrology Institute, Schneider Children's Medical Center, Tel Aviv, Israel, 3Nephrology, Boston Children's Hospital, Boston, MA, 4Children's Hospital Association, Lenexa, KS

    *Purpose: Choice of induction agent at the time of pediatric kidney transplant (KTx) is often based upon patient characteristics and center practice. There are limited…
  • 2021 American Transplant Congress

    Center Use of Technical Variant Grafts Impacts Pediatric Liver Transplant Waitlist and Recipient Outcomes in the United States

    G. Mazariegos1, E. R. Perito2, J. Squires1, K. Soltys1, A. Griesemer3, S. A. Taylor4, E. Pahl5

    1Childrens Hosp of Pittsburgh, Pittsburgh, PA, 2UCSF, San Francisco, CA, 3Columbia University Irving Medical Center, New York, NY, 4Lurie Children's Hospital of Chicago, Chicago, IL, 5Omnilife, Lexington, KY

    *Purpose: Assessing composite outcome measures are critical when evaluating graft type selection in pediatric liver transplantation (LT).*Methods: OPTN data on children listed for first-time LT…
  • 2021 American Transplant Congress

    Single-Cell RNA-seq Identifies Intra-Graft Population Heterogeneity in Acute Heart Allograft Rejection in the Mouse

    C. Wu1, Y. Tang1, X. Shi1, X. He1, X. Li2

    1The First Affiliated Hospital,Sun Yat-sen University, Guangzhou, China, 2Immunobiology & Transplant Sciences Houston Methodist Hospital, Houston, TX

    *Purpose: Transplant rejection remains a major barrier to graft survival and involves a diversity of cell types. But the heterogeneity in a given cell type…
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