2021 American Transplant Congress
Impact of Covid-19 in Transplant Care: Attitudes, Feeling and Behaviors of Liver, and Kidney Pre and Post Transplant Patients
Beth Israel Deaconess Medical Center, Boston, MA
*Purpose: The SARS-CoV-2(COVID-19) pandemic poses unique challenges for transplant patients, which may impact their attitudes, emotions and behaviors associated with transplant care. This study surveys…2021 American Transplant Congress
Impact of Extended Living Donor Criteria on Donor Safety in Living Donor Liver Transplantation
Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea, Republic of
*Purpose: Donor safety is major concern during living donor liver transplantation (LDLT) and most transplant centers accept strict selection criteria although some centers have been…2021 American Transplant Congress
The Learning Curve Associated with De Novo Tacrolimus XR Use in a Racially Diverse Kidney Transplant Population
Medical University of South Carolina, Charleston, SC
*Purpose: Tacrolimus XR (LCP-Tac) was approved for de novo dosing in kidney transplant recipients in 2018. In 2020, our center was challenged with a nationwide…2021 American Transplant Congress
MDR-101-MLK-MERCURY Kidney Transplant Tolerance Study Update
*Purpose: We report interim results of the Phase 3 MERCURY tolerance study, which produces mixed chimerism and ultimately generates operational tolerance allowing for the elimination…2021 American Transplant Congress
Late Subclinical Rejection and Borderline Rejection in Kidney Transplant Patients is Associated with Increased Incidence of Subsequent Clinical Rejections
*Purpose: The outcomes of inflammatory changes noted in late surveillance biopsies (1 year) is unclear.*Methods: Patients transplanted (live donor and deceased donor) at our center…2021 American Transplant Congress
Limited Immunogenicity of a Single Dose of Sars-cov-2 Mrna Vaccine in Solid Organ Transplant Recipients
*Purpose: Given substantial challenges with vaccine allocation and evidence for short-term vaccine efficacy after a single dose of SARS-CoV-2 mRNA vaccines in clinical trials, some…2021 American Transplant Congress
Successful Induction of Hematopoietic Chimerism by Dual Inhibition of Mcl-1 and Bcl-2 Without Myeloablative Treatments in Nonhuman Primates
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA
*Purpose: Induction of hematopoietic chimerism by donor bone marrow transplantation (BMT) is essential for achievement of allograft tolerance in clinical HLA mismatched kidney transplantation, while…2021 American Transplant Congress
Clinical Outcomes Associated with Induction Therapy Regimens for Kidney Transplantation in Children: A NAPRTCS and PHIS Collaborative Report
*Purpose: Choice of induction agent at the time of pediatric kidney transplant (KTx) is often based upon patient characteristics and center practice. There are limited…2021 American Transplant Congress
Center Use of Technical Variant Grafts Impacts Pediatric Liver Transplant Waitlist and Recipient Outcomes in the United States
*Purpose: Assessing composite outcome measures are critical when evaluating graft type selection in pediatric liver transplantation (LT).*Methods: OPTN data on children listed for first-time LT…2021 American Transplant Congress
Single-Cell RNA-seq Identifies Intra-Graft Population Heterogeneity in Acute Heart Allograft Rejection in the Mouse
*Purpose: Transplant rejection remains a major barrier to graft survival and involves a diversity of cell types. But the heterogeneity in a given cell type…
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