2021 American Transplant Congress
Resolution of Endothelial Inflammation is Delayed Following IFNγ, Which Provokes a Long-lasting Pro-adhesive Phenotype Dependent on JAK/STAT Signaling
Pathology and Laboratory Medicine, UCLA, Los Angeles, CA
*Purpose: Although many cytokines are upregulated within allografts undergoing rejection, intragraft transcripts are dominated by IFN-response signatures. Resolution is a key phase of inflammation needed…2021 American Transplant Congress
Transcriptomics and Proteomics Profiling of Complement Pathway (cp) Proteins in Biopsies With Polyomavirus Bk Nephropathy (bkvn)
*Purpose: Late stage BKVN can show C4d as well as classic immune complex deposits in the tubular basement membranes (Bracamonte et al. Am J Transplant…2021 American Transplant Congress
Impact of a Latinx Kidney Transplant Clinic
Abdominal Transplant Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC
*Purpose: To evaluate the impact of a Latinx clinic in our institution. With a growing increase of end stage renal disease (ESRD)in the Latino population…2021 American Transplant Congress
Detection of SARS-CoV-2 Specific Functional T Cells Using a Seven Color Flow Cytometry Assay
Eurofins-Viracor, Lees Summit, MO
*Purpose: The need to evaluate SARS-CoV-2 immune responses is an important clinical research focus. Detecting neutralizing antibodies is one measure of immune response, but the…2021 American Transplant Congress
A Comparison of Plasmapheresis Methods in the Treatment of Late Antibody Mediated Rejection
*Purpose: Effective management to prevent allograft loss after late antibody mediated rejection (ABMR) in kidney transplant (KTx) recipients remains a vexing clinical challenge. While plasma…2021 American Transplant Congress
Double Negative T Cells Mediate Cd39-Dependent Protection in Hepatic Ischemia and Reperfusion Injury
*Purpose: Hepatic ischemia and reperfusion injury (HIRI) is a significant cause of morbidity and mortality following liver transplantation and major hepatic resections. Double negative T…2021 American Transplant Congress
Transplant Glomerulopathy in the Absence of Donor-specific HLA Antibodies: Risk Factors, Histopathological Features and Graft Outcome
Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
*Purpose: Transplant glomerulopathy (TG) is established as a hallmark of chronic antibody-mediated rejection in kidney transplant patients with donor-specific HLA antibodies (HLA-DSA). The clinical importance…2021 American Transplant Congress
The Predictive Factors of Survival in Re-listed Patients Who Received Initial Liver Transplants Using Donation After Circulatory Death Grafts
Cleveland Clinic, Cleveland, OH
*Purpose: The inherent risk of livers from donors after circulatory death (DCD) is well known such as primary non-function (PNF) and increased rates of biliary…2021 American Transplant Congress
Neutrophil Extracellular Trap-induced Thrombotic Microangiopathy in Steatotic Mouse Recipients Impacts Liver Transplant Outcomes
UCLA Medical Center, Los Angeles, CA
*Purpose: Nonalcoholic steatohepatitis (NASH) is an emerging global epidemic projected to become the leading indication for liver transplantation (LT). Although recent studies focus on the…2021 American Transplant Congress
The Risk of Post-donation Kidney Function Impairment for Prospective Living Kidney Donors with Persistent Isolated Microscopic Hematuria
*Purpose: According to current guidelines, a kidney biopsy is indicated in prospective living kidney donors who present with persistent isolated microscopic hematuria (PIMH) during evaluation,…
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