ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Immunosuppression Regimen and Risk of Posttransplant Diabetes Among Older Kidney Transplant Recipients

    K. Lentine1, J. Ahn2, M. McAdams Demarco2, H. Xiao1, S. Bunnapradist3, D. Segev2, D. Axelrod1, S. Bae2, V. Dharnidharka4, Y. Caliskan1, S. Chang4, G. Hess5, J. Snyder6, M. Schnitzler1

    1Saint Louis Univ, Saint Louis, MO, 2Johns Hopkins, Baltimore, MD, 3Univ of California, Los Angeles, Los Angeles, CA, 4Washington Univ, Saint Louis, MO, 5Drexel Univ, Philadelphia, PA, 6SRTR, Minneapolis, MN

    *Purpose: Posttransplant diabetes mellitus (PTDM) is a common complication after kidney transplantation (KTx), which may be exacerbated by immunosuppressive therapy (ISx). Older adults tend to…
  • 2021 American Transplant Congress

    Belatacept Conversion in Elderly Renal Transplant Recipients

    M. Durst1, D. Felix1, M. Jorgenson1, J. Descourouez1, B. C. Astor2, D. Mandelbrot2

    1UW Health, Madison, WI, 2University of Wisconsin School of Medicine and Public Health, Madison, WI

    *Purpose: Describe the impact of conversion from a calcineurin inhibitor (CNI) based immunosuppressive regimen to belatacept in elderly renal transplant recipients.*Methods: Adult renal transplant patients…
  • 2021 American Transplant Congress

    Frailty Component Trajectories Among Kidney Transplant Recipients

    N. Chu, X. Chen, D. Segev, M. McAdams-DeMarco

    Johns Hopkins, Baltimore, MD

    *Purpose: Frailty is associated with decreased access to kidney transplantation (KT) and poor post-KT outcomes. Little is known about how an acute stressor, like KT,…
  • 2021 American Transplant Congress

    The Impact of Donor Age and Donor-Recipient Age Difference on Living Donor Kidney Transplantation

    T. Hiramitsu1, T. Tomosugi2, K. Futamura2, M. Okada2, N. Goto2, T. Ichimori2, S. Narumi2, Y. Watarai2

    1Nagoya Daini Red Cross Hospital, Myokencho Showaku, Japan, 2Nagoya Daini Red Cross Hospital, Nagoya, Japan

    *Purpose: The impact of donor age and donor-recipient age difference on living donor kidney transplantation have not been investigated simultaneously.*Methods: A total 805 adult living…
  • 2021 American Transplant Congress

    Initial Experience with Single-port Robotic-assisted Kidney Transplantation

    M. Eltemamy, A. Aminsharifi, Y. Lin, Z. Schwen, M. Abou Zeinab, V. Krishnamurthi, D. Goldfarb, A. Wee, J. Kaouk

    Cleveland Clinic, Cleveland, OH

    *Purpose: Early experiences with multi-port robotic kidney transplantation have demonstrated a potential reduction in complications and improved convalescence while maintaining equivalent functional outcomes relative to…
  • 2021 American Transplant Congress

    Development and Validation of a Nomogram for Remnant Kidney Function After Living-donor Donation

    M. Dou, P. Tian, B. Zheng, G. Deng, Y. Shi, C. Ding

    The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China

    *Purpose: This study was to develop and validate a nomogram to predict remnant kidney function after living-donor kidney donation.*Methods: We conducted a retrospective cohort study…
  • 2021 American Transplant Congress

    Maternal Perinatal Condition and Neonatal Growth and Development After Renal Transplantation

    X. Feng, T. Song, Q. Zhong, J. Zeng, X. Wang, Y. Fan, Z. Huang, T. Lin

    Department of Urology, Institute of Urology, Organ Transplantation Center, West China Hospital, Sichuan University, Chengdu, China

    *Purpose: Although pregnancy and delivery after kidney transplantation have been reported in many studies , it is still little known about growth and development of…
  • 2021 American Transplant Congress

    Clinical Validation and Performance of Donor-Derived Cell-Free DNA in Allograft Rejection

    S. Anand1, A. Pai2, J. S. Bromberg3, G. Gupta4, I. Moinuddin4, T. Alhamad5, V. Bowers6, S. Ghosh7, W. Tian7, L. Bu8, E. Stites9

    1Intermountain Medical Center, Murray, UT, 2University of Texas McGovern Medical School, Houston, TX, 3University of Maryland School of Medicine, Baltimore, MD, 4Virginia Commonwealth University, Richmond, VA, 5Washington University in St. Louis, St. Louis, MO, 6Tampa General Hospital, Tampa, FL, 7CareDx, Brisbane, CA, 8University of Minnesota, Minneapolis, MN, 9University of Colorado, Aurora, CO

    *Purpose: Extensive literature regarding the utility of donor-derived cell-free DNA (dd-cfDNA) shares various thresholds for active rejection (AR) based on differing data sets for both…
  • 2021 American Transplant Congress

    Detection of Rejection in Kidney Transplant Patients Using an Algorithm That Combines Donor Fraction and Absolute Donor-derived Cell-free DNA

    S. Bunnapradist1, E. Ahmed2, M. Maninder2, Z. P. Demko2, P. R. Billings2, H. Tabriziani2, P. Gauthier3

    1David Geffen Sch of Med @ UCLA, Los Angeles, CA, 2Natera, Inc., San Carlos, CA, 3Natera, Inc., Los Angeles, CA

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) in the plasma of renal allograft patients is a clinically validated biomarker for allograft injury and rejection. Several dd-cfDNA assays…
  • 2021 American Transplant Congress

    Hypercholesterolemia and Donor Age Impaired Capillary Vegf and Nitric Oxide (no) Expression and in Turn Decrease Both Microvascular Density and Tubule Villin Expression in Renal Allografts, Resulting in Poor Graft Survival

    B. Ozdemir1, E. Akcay1, A. Ok Atilgan1, M. Haberal2

    1Department of Pathology, Baskent University, Ankara, Turkey, 2Division of Transplantation, Department of General Surgery, Baskent University, Ankara, Turkey

    *Purpose: The role of aging and hypercholesterolemia (HC) on endothelial cells (ECs) are not well defined. Aged ECs might produce less NO and VEGF, resulting…
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