2021 American Transplant Congress
Precision Medicine Tools in Kidney Transplant (KTx): Implications for Individualized Immunosupression Therapy and Downstream Cost-savings
Intermountain Medical Center, Murray, UT
*Purpose: Kidney Tissue Transcriptomics (Tr) is an emerging adjunct to traditional histology for diagnosis of kidney rejection in KTx. The objective assessment and reliance on…2021 American Transplant Congress
Status of Kidney Allocation in Liver-kidney Transplants Before and After the UNOS/OPTN Policy
Department of Internal Medicine: Division of Transplant Nephrology, UCLA, Los Angeles, CA
*Purpose: On August 10, 2017 the United Network for Organ Sharing (UNOS) enacted policies 9.7 and 8.5G to establish medical criteria for simultaneous liver-kidney (SLK)…2021 American Transplant Congress
High Degree of Center Variation in Simultaneous Heart Kidney Transplant: Opportunities for Standardization
*Purpose: Simultaneous heart kidney transplant (SHK) is increasingly common and unregulated. We sought to understand variation in patient selection for SHK at the center level.*Methods:…2021 American Transplant Congress
SARS-CoV-2 Antibody Response After Induction Therapy in Kidney Transplant Recipients
*Purpose: SARS-CoV-2 antibody prevalence in kidney transplant recipients is beginning to be reported, although little is known about the humoral immune response in the immediate…2021 American Transplant Congress
Kidney Paired Donation in Pediatrics: An Underused Opportunity?
*Purpose: Kidney paired donation (KPD) provides the opportunity for ABO-mismatched or HLA-incompatible pairs to receive a living donor kidney transplant. The superior graft survival among…2021 American Transplant Congress
Assessing the Accuracy of the Lung Allocation Score
1University of Chicago, Chicago, IL, 2University of Wisconsin-Madison, Madison, WI
*Purpose: The Lung Allocation Score (LAS) relies on the performance of two cox proportional hazards models that estimate waitlist and post-transplant survival. These models were…2021 American Transplant Congress
Comparison of Outcomes of Hepatitis C Virus (hcv) Nucleic Acid (nat) Positive Donor Between Hcv-naïVe and Hcv + Recpients – A Donor Mate Analysis
University of Virginia, Charlottesville, VA
*Purpose: Despite a growing mismatch between organ need and supply, organs from HCV+ donors were only offered to HCV+ recipients (HCV R+) to avoid complications…2021 American Transplant Congress
Anti-CD8 Immuno-PET for Non-invasive Tracking of Early Graft Rejection in a Non-human Primate Kidney Transplant Model
*Purpose: Infiltration of CD8 T cells into solid organ grafts is an early sign of rejection. REGN5054 is a fully human monoclonal antibody that binds…2021 American Transplant Congress
Validation of a Novel Gene Expression Biomarker of Rejection Following Liver Transplantation
*Purpose: Non-invasive biomarkers distinguishing early signs of immune activation vs. quiescence could more objectively guide immunosuppression management after liver transplantation (LT). Our aim was to…2021 American Transplant Congress
The Rate of Hospitalization Among Patients with Cirrhosis is More Than Twice as High as Patients Over 85 Years
*Purpose: Cirrhosis is a common disease however it is understudied because population data on patients with cirrhosis is lacking. While the risk of hospitalization in…
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