ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    The Pleural Cavity, A Novel and Clinically Relevant Site for Pancreatic Islet Transplantation

    Q. Yuan1, K. Lee1, C. Rickert1, S. Hong1, E. Acheampong1, E. Szuter1, Y. Xu2, K. Deng1, N. Feeney1, Q. Fu1, G. Huai1, J. Lei1, I. Rosales1, P. Russell1, J. Madsen1, R. Colvin1, A. Alessandrini1, J. Markmann1, -. Q.Y. and K.L.3, -. A.A. and J.F.M.4

    1Massachusetts General Hospital, Boston, MA, 2Chinese PLA General Hospital & Medical School, Beijing, China, 3Co-First Authors, Boston, MA, 4Co-Senior Authors, Boston, MA

    *Purpose: Islet transplantation currently provides a cure for type 1 diabetes. Hepatic infusion of islets via the portal vein is clinically accepted in human, although…
  • 2020 American Transplant Congress

    Unique Podocyte and Multiplex Single-Cell RNASeq Analysis of Paired Sera and Bone Marrow Samples Suggest a Role for Perturbed Hematopoeitic Progenitors in FSGS Recurrence

    P. Rashmi, T. Sigdel, A. Alica Da Silva, R. Paul, D. Galligan, J. Wolfe, F. Vincenti, M. Sarwal

    University of California San Francisco, San Francisco, CA

    *Purpose: Focal Segmental Glomerulosclerosis (FSGS) is the most common cause of nephrotic syndrome, can lead to ESRD, and carries a high burden of recurrence risk…
  • 2020 American Transplant Congress

    Prevalence of Risk Factors for NAFLD among Living Liver Donors

    D. A. Axelrod1, M. Simpson2, E. Pomfret3, A. Ehrlich4, S. Rwema4, R. Chung4, F. Gordon5

    1Surgery, University of Iowa, Iowa CIty, IA, 2Surgery, Lahey Clinic, Burlington, MA, 3University of Colorado, Denver, CA, 4Mass General Hospital, Boston, MA, 5Lahey, Burlington, MA

    *Purpose: The development of non-alcoholic fatty liver (NAFLD) disease has been strongly associated with the presence of polymorphisms in PNPLA3 rs738409. When compared with wild…
  • 2020 American Transplant Congress

    Renal Transplant Induction Therapy Safety Outcomes Comparison

    R. M. Hofmann1, J. Combs2, K. J. Schmidt3, T. Dyckman4

    1Nephrology, Renal Associates of West Michigan, Grand Rapids, MI, 2Pharmacy/Transplant, Mercy Health St. Mary's, Grand Rapids, MI, 3Pharmacy, Ferris State University College of Pharmacy, Big Rapids, MI, 4Pharmacy, Mercy Health St. Mary's, Grand Rapids, MI

    *Purpose: Induction immunosuppression with alemtuzumab and rabbit anti-thymocyte globulin (r-ATG) reduces acute rejection following kidney transplantation. Efficacy is thought to be similar between the agents…
  • 2020 American Transplant Congress

    Severity of Donor Acute Kidney Injury Does Not Impact Long-Term Outcomes in Deceased Donor Renal Transplant Recipients

    A. Brar1, A. Gruessner2, D. Adey1, M. Salifu2

    1University of California, San Francisco, San Francisco, CA, 2SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Kidneys with increased donor terminal creatinine are frequently discarded. This study used national data to assess renal allograft and patient outcomes in deceased donor…
  • 2020 American Transplant Congress

    Safety and Efficacy of Direct-Acting Oral Anticoagulants versus Warfarin in Kidney Transplant Recipients

    A. L. Bixby1, S. A. Shaikh2, A. S. Naik3, L. Cotiguala3, K. McMurry3, M. D. Samaniego-Picota4, V. D. Marshall5, J. M. Park3

    1University Hospitals Cleveland Medical Center, Cleveland, OH, 2Keck Medical Center of USC, University of Southern California, Los Angeles, CA, 3Michigan Medicine, Ann Arbor, MI, 4Henry Ford Transplant Institute, Detroit, MI, 5University of Michigan College of Pharmacy, Ann Arbor, MI

    *Purpose: Safety and efficacy of direct-acting oral anticoagulants (DOACs) have not been well studied in solid organ transplant. The purpose of our study was to…
  • 2020 American Transplant Congress

    Failure to Launch; a Multi-Centre Study of Potential Live Donors in Southeast Nigeria

    C. G. Okwuonu1, G. O. Achor2, Q. L. Ogana3, C. Kingsley4

    1Internal Medicine, Federal Medical Centre, Umuahia, Nigeria, 2Department of Surgery, Federal Medical Centre, Umuahia, Nigeria, 3Internal Medicine, Beatitudes Mediplex and Kidney Care Centre, Umuahia, Nigeria, 4Internal Medicine, Beatitudes Mediplex and Kidney Care Centre, Aba, Nigeria

    *Purpose: To determine the socio-demographic characteristics of potential living kidney donors, donor motivation, incidental findings on clinical evaluation and some identified factors that precluded eventual…
  • 2020 American Transplant Congress

    Major Adverse Cardiovascular Events (MACE) in Living Kidney Donors (LKDs)

    M. Merzkani1, A. Denic1, M. D'Costa1, L. Ricaurte1, R. Narasimhan1, X. Benavides1, A. Mullan1, J. Larson1, W. Park1, M. P. Alexander1, H. Chakkera2, S. Textor1, S. Taler1, M. Stegall1, N. Issa1, A. Rule1

    1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Scottsdale, AZ

    *Purpose: There is limited knowledge regarding long-term cardiovascular outcomes in living kidney donors. We performed a multicenter study assessing baseline risk factors that increase MACE…
  • 2020 American Transplant Congress

    “By the Time They Get to Me, I’ll Be Dead Anyway” – A Mixed-Methods Examination of Treatment Education & Decision-Making among Patients with Varying Amounts of Pre-End-Stage Renal Disease Nephrology Care

    M. Urbanski1, L. Dumenci1, C. Gadegbeku2, L. Siminoff1, A. Waterman3, H. Gardiner1

    1College of Public Health, Temple University, Philadelphia, PA, 2Lewis Katz School of Medicine, Section of Nephrology, Hypertension, and Kidney Transplantation, Temple University, Philadelphia, PA, 3UCLA, Division of Nephrology, Los Angeles, CA

    *Purpose: The aim of this study was to explore renal replacement therapy (RRT) knowledge and decision-making experiences and preferences among patients with varying amounts of…
  • 2020 American Transplant Congress

    Delayed Graft Function in the Recipients of Simultaneous Liver and Kidney Transplant: A Single-Center Experience

    F. Aziz, B. Muth, N. Garg, M. Mohamed, D. Mandelbrot, J. Mezrich, A. Djamali, S. Parajuli

    University of Wisconsin, Madison, WI

    *Purpose: Increased rates of delayed graft function (DGF) have been reported in the recipients of simultaneous liver and kidney (SLK) transplant. However, the effect of…
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