ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    C-Reactive Protein 1-Year Post-Transplant is Associated with Future Development of Coronary Artery Vasculopathy and Rejection in a Pediatric Heart Transplant Cohort

    H. J. Tadros, A. H. Bashir, F. J. Fricker, B. A. Pietra, D. Gupta

    Congenital Heart Center/Pediatrics, University of Florida, Gainesville, FL

    *Purpose: Coronary artery vasculopathy (CAV) is one of the leading causes of mortality beyond 3y post-transplant (OHT). Multiple risk factors are associated with development of…
  • 2020 American Transplant Congress

    Molecular Profiles of Injury in Heart Transplant Allograft: Relationship to Rejection, Ejection Fraction, and Survival

    P. Halloran1, J. Reeve2, &. the INTERHEART Study Group3

    1University of Alberta, Edmonton, AB, Canada, 2Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 3., ., AB, Canada

    *Purpose: In previous studies we used microarray analysis of gene expression to identify rejection in heart transplant endomyocardial biopsies, and found that this also revealed…
  • 2020 American Transplant Congress

    Conversion to Belatacept in HIV(+) Renal Transplant Recipients

    A. Santeusanio, A. Bhansali, R. Shapiro, G. De Boccardo

    Mount Sinai Hospital, New York, NY

    *Purpose: HIV(+) renal transplant recipients were excluded from phase III trials of belatacept, and currently there are only scattered case reports.*Methods: This was a single…
  • 2020 American Transplant Congress

    Parathyroidectomy Remains Effective for Treating Tertiary Hyperparathyroidism: Long-Term Results of a Randomized Study

    A. Coloma1, P. Moreno2, J. Torregrosa3, N. Montero1, A. Manonelles1, E. Melilli1, J. Cruzado1

    1Nephrology, Hospital Universitari de Bellvitge, Hospitalet de LLobregat, Spain, 2Surgery, Hospital Universitari de Bellvitge, Hospitalet de LLobregat, Spain, 3Nephrology, Hospital Clinic, Barcelona, Spain

    *Purpose: Tertiary hyperparathyroidism is a common cause of hypercalcemia after kidney transplant (KT). The aim of this study is to evaluate the long-term effectiveness of…
  • 2020 American Transplant Congress

    High Intra-Patient Variability of Tacrolimus in Pediatric and Adolescent Renal Transplant Recipients is Associated with Worse Graft Outcomes

    K. Piburn1, L. Maestretti2, R. Shetty2, M. V. Patton2, A. McGrath2, W. Concepcion1, A. Chaudhuri1, P. C. Grimm1, V. K. Sigurjonsdottir3

    1Stanford University, Palo Alto, CA, 2Lucile Packard Children's Hospital Stanford, Palo Alto, CA, 3Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland

    *Purpose: High intra-patient variability (IPV) in tacrolimus (TAC) levels is associated with de novo donor-specific antibodies (dnDSA) and graft loss. We examined the natural history…
  • 2020 American Transplant Congress

    Comparative Review of Adult Kidney Transplant Medicare Cost Report Reimbursement in U. S. Transplant Hospitals

    E. Zavala1, J. Rogers2, S. Karp1

    1Vanderbilt University Medical Center, Nashville, TN, 2Transplant Management Group, San Diego, CA

    *Purpose: Medicare organ acquisition reimbursement (MOAR) from the Medicare Cost Report (MCR) includes but is not limited to costs associated with candidate evaluation, maintenance on…
  • 2020 American Transplant Congress

    Textbook Outcome as a Composite Quality Metric in Kidney Transplantation

    J. L. Han, A. J. Logan, J. M. Sneddon, G. L. Brock, K. W. Washburn, A. D. Schenk

    Department of Surgery, Division of Transplantation, The Ohio State University Wexner Medical Center, Columbus, OH

    *Purpose: Textbook outcomes (TO) describe ideal patient outcomes following specific surgical procedures and are useful composite quality metrics for patients, providers and payors. We aimed…
  • 2020 American Transplant Congress

    Muscle-Liver Crosstalk via the Myokine MG53 Plays a Critical Role in Hepatocellular Repair

    C. Akateh, J. Ko, B. F. Reader, J. Kim, Y. Lee, B. A. Whitson, J. Ma, S. M. Black

    The Ohio State University Wexner Medical Center, Columbus, OH

    *Purpose: Transplantation remains the only effective treatment for end-stage liver disease, but the number of organs deemed suitable for transplantation falls far short of the…
  • 2020 American Transplant Congress

    Single-Cell RNA Sequencing to Assess the Effect of IL-6 Receptor Blockade in Kidney Transplantation

    A. Zarinsefat, P. Rashmi, A. Da Silva, T. Sigdel, S. Chandran, Q. Tang, J. Ye, F. Vincenti, M. Sarwal

    University of California San Francisco, San Francisco, CA

    *Purpose: Prospective randomized study of IL-6R blockade with Tocilizumab for treatment of subclinical inflammation (SCI) in renal transplantation, reveals unique profiles of resting and stimulated…
  • 2020 American Transplant Congress

    Stability of T Reg with Combination of mTOR Inhibitors with Belatacept in Reducing Risk of Acute Rejection in Kidney Transplant

    J. Shoji, J. Leung, Q. Tang, F. Vincenti

    University of California San Francisco (UCSF), San Francisco, CA

    *Purpose: Belatacept is a costimulatory blocker that is used as de novo maintenance immunosuppression in kidney transplantation to avoid toxic effects of calcineurin inhibitors and…
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