Am J Transplant, Volume 20, Suppl 3 Archives - Page 28 of 223 - ATC Abstracts

2020 American Transplant Congress
Epidemiology of Invasive Fungal Infections in Heart Transplant Recipients
A. Couture-Cossette¹, A. Puing¹, A. Multani², O. Quintero¹, A. K. Subramanian¹, E. Henricksen³, R. Lee¹, Y. Moayedi⁴, K. Khush⁵, J. J. Teuteberg⁵, D. Y. Ho¹
¹Department of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, ²Department of Infectious Diseases, UCLA, Stanford, CA, ³Pharmacy, Stanford Healthtcare, Stanford, CA, ⁴Department of Cardiology, UHN, Toronto, ON, Canada, ⁵Division of Cardiology, Department of Medicine, Stanford University, Stanford, CA
*Purpose: The incidence and epidemiology of invasive fungal infections (IFI) after heart transplantation (HTx) are influenced by changes in environmental exposures, immunosuppression, and prophylaxis practices.…
2020 American Transplant Congress
Preemptive Direct Acting Antiviral Therapy as Prophylaxis in Donor HCV-Positive to Recipient HCV-Negative Solid Organ Transplant: a Comprehensive Review
M. Mavuram, S. Mavuram, H. Samant, S. Pandit, B. Samant, J. Morris, J. Alexander
Gastroenterology, Louisiana State University of Health Sciences Shreveport, Shreveport, LA
*Purpose: With the advent of highly effective and safe oral Direct acting Antiviral agents (DAAs), several transplant centers have adopted protocols for using HCV positive…
2020 American Transplant Congress
Recipient Outcomes of DCD Kidneys with and without Donor TPA Administration
E. Shipman, W. De Faria, L. Preczewski, R. Vianna, G. Guerra
Miami Transplant Institute, Miami, FL
*Purpose: Our OPO utilizes a TPA administration protocol for DCD liver donors to be transplanted at our center. This results in a series of DCD…
2020 American Transplant Congress
Bypassing the Nearest Transplant Center for Care is Associated with Gains in Time to Living Donor but Not Deceased Donor Kidney Transplantation or Improved Graft Outcomes
A. M. Whelan¹, C. McCulloch², E. Ku¹
¹Division of Nephrology, University of California San Francisco (UCSF), San Francisco, CA, ²Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA
*Purpose: Some patients may gain an advantage if they choose to bypass their local transplant center and receive care at a center further away but…
2020 American Transplant Congress
Sensitization via Pregnancy Generates Alloantibody and Cross-Reactive Xeno-Antibody in a Non-Human Primate Model
J. Yoon, M. Manook, Z. Fitch, R. Schmitz, A. Choi, A. M. Jackson, S. Knechtle, J. Kwun
Surgery, Duke University, Durham, NC
*Purpose: Women are disproportionately represented among highly sensitized waitlist candidates and within HLA-incompatible transplantation programs. Due to difficulties obtaining compatible donors, sensitized patients are seen…
2020 American Transplant Congress
Comparing Two Methods of Minimally-Ischemic Cardiac Preservation in Life-Supporting Cardiac Xenotransplantation Model
C. E. Goerlich¹, A. Singh¹, D. Kaczorowski¹, M. Abdullah¹, B. Lewis¹, I. Tatarov¹, A. Hershfeld¹, T. Zhang¹, E. Strauss¹, P. Odonkor¹, B. Williams¹, D. Ayares², B. Griffith¹, M. Mohiuddin¹
¹Surgery, University of Maryland School of Medicine, Baltimore, MD, ²Surgery, Revivicor, Blacksburg, VA
*Purpose: Transplantation of organs from animals to humans (xenotransplantation) has been proposed to address the critical shortage of organs for transplantation. The use of genetically…
2020 American Transplant Congress
Increased Intra-Abdominal Pressure is Associated with Delayed Graft Function after Kidney Transplantation
A. Coca¹, C. Arias-Cabrales², M. Perez-Saez², P. Gonzalez¹, M. Crespo², M. Rollan¹, B. Toribio¹, A. Mendiluce¹, J. Pascual², J. Bustamante-Munguira³
¹Nephrology, Hospital Clínico Universitario, Valladolid, Spain, ²Nephrology, Hospital Del Mar, Barcelona, Spain, ³Cardiac Surgery, Hospital Clínico Universitario, Valladolid, Spain
*Purpose: Increased intra-abdominal pressure (IAP) is a common complication among critically ill and post-surgical patients that can cause organ dysfunction. Its prevalence and effects after…
2020 American Transplant Congress
Hepatocyte Growth Factor (HGF) Prevents the Apoptotic and Anti-Angiogenic Effect of Hypercholesterolemia on Hepatocytes in Liver Allografts
H. B. Ozdemir¹, G. Ozgun¹, A. Yucel Polat¹, N. Haberal¹, G. Moray², M. Haberal²
¹Pathology, Baskent University, Ankara, Turkey, ²Department of General Surgery, Division of Transplantation, Baskent University, Ankara, Turkey
*Purpose: Background: Hypercholesterolemia (HC) impairs angiogenesis and induces apoptosis in livers. This hyperlipidemic impairment of angiogenesis reported associated with reduced bFGF. HGF stimulates proliferation, angiogenesis,…
2020 American Transplant Congress
Identifying Factors Associated with Delayed Graft Function Severity Using the OPTN Database
K. Checchi¹, D. Stewart², A. Toll², J. Case¹, S. Kurian¹, C. Marsh¹
¹Scripps Health, La Jolla, CA, ²United Network for Organ Sharing Research Department, Richmond, VA
*Purpose: Delayed graft function (DGF) is a costly adverse outcome in kidney transplantation with negative implications for both graft and patient survival. Identifying factors associated…
2020 American Transplant Congress
Transplant Relevant MDSC Genetics: Differential Gene Expression Profiles of Immunosuppressive Myeloid-Derived Suppressor Cells Induced by Granulocyte-Colony Stimulating Factor
Y. S. Lee, J. S. Bromberg, J. R. Scalea
Department of Surgery, University of Maryland, Baltimore, MD
*Purpose: Myeloid-derived suppressor cells (MDSC) are expanded in inflammation conditions and can control alloreactive T cell responses. Granulocyte-colony stimulating factor (GCSF) is known to induce…