Am J Transplant, Volume 20, Suppl 3 Archives - Page 28 of 223 - ATC Abstracts

2020 American Transplant Congress
The Role of CXCL16/CXCR6 in Mediating Macrophage Chemotaxis and M1 Macrophage Polarization in Murine Renal Ischemia Reperfusion Injury
W. Zhang¹, X. Zhang², G. Tu², C. Yang¹, G. Qi¹, M. Xu¹, T. Zhu¹
¹Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China, ²Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China
*Purpose: The objective of this study is to investigate the role of Chemokine (C-X-C motif) ligand 16 (CXCL16) and its unique receptor C-X-C chemokine receptor…
2020 American Transplant Congress
Does Hope for a Better Future or Fear of Death Motivate Kidney Patients More? A Decisional Balance Exploration of Motivation to Pursue Living Donor Kidney Transplant
H. Rafiqzad¹, A. Wasim¹, A. Rezaeishahreza¹, J. Lam¹, A. Li¹, T. Mahiuddin¹, A. D. Waterman², M. Novak¹, I. Mucsi¹
¹University Health Network, Toronto, ON, Canada, ²University of California, Los Angeles, Los Angeles, CA
*Purpose: We assessed whether the importance attributed to “living a longer life with transplant” versus “fear of death during transplant surgery” by kidney transplant (KT)…
2020 American Transplant Congress
Crosstalk between TLR4 and HLA Class I Mediates P-Selectin Expression and Monocyte Capture to Endothelial Cells
Y. Jin, N. M. Valenzuela, R. A. Sosa, E. F. Reed
Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, CA
*Purpose: Transplant recipients developing donor specific HLA antibodies (DSA) are at risk for acute and chronic antibody-mediated rejection (AMR). DSA contribute to the process of…
2020 American Transplant Congress
The FcγRIIIa-158 VV Genotype Increased the Risk of Post-Transplant Lymphoproliferative Disorder in T-Cell Depleted Kidney Transplant Recipients
P. Gatault¹, L. Lajoie¹, J. Stojanova², P. Marquet², G. Thibault¹
¹CHU Tours, Tours, France, ²CHU Limoges, Limoges, France
*Purpose: Post-transplantation lymphoproliferative disorder (PTLD) is a severe complication in organ transplant recipients. The use of T lymphocyte-depleting antibodies (TLDAb), especially rabbit TLDAb contributes to…
2020 American Transplant Congress
Kidney Paired Donation Outcomes among High PRA Recipients
A. Thomas¹, A. Shaffer², M. Henderson², D. Segev²
¹University of North Carolina, Chapel Hill, NC, ²Johns Hopkins, Baltimore, MD
*Purpose: Kidney paired donation (KPD) accounts for an increasing amount of living donor transplants in the US. Previous studies have shown equivalent outcomes between transplants…
2020 American Transplant Congress
What Are the Peri-Operative and Longterm Outcomes of Utilizing Donation after Circulatory Death Livers with Macrosteatosis? A Multicenter Analysis
K. Croome¹, A. Mathur², S. Mao¹, B. Aqel³, P. Senada¹, J. Piatt¹, J. Heimbach⁴, A. Moss³, C. Rosen⁴, C. Taner¹
¹Mayo Clinic Jacksonville, Jacksonville, FL, ²Mayo Clinic Arizona, Scotsdale, AZ, ³Mayo Clinic Arizona, Scottsdale, AZ, ⁴Mayo Clinic Rochester, Rochester, MN
*Purpose: Given the potentially additive risk from using donor livers that are both steatotic and from a donation after circulatory death(DCD) donor, there is a…
2020 American Transplant Congress
Can Biliary Internal Stents Reduce Biliary Complications in Adult Liver Transplantation?
Y. Kwon¹, Y. S. Genyk¹, Y. Yoon²
¹Division of Hepatobiliary, Pancreas, and Abdominal Organ Transplant, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, ²Division of Hepatobiliary, Pancreas, and Abdominal Organ Transplant, Department of Surgery, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea, Republic of
*Purpose: Biliary complications remain a consistent cause of morbidity and mortality in liver transplant (LT) recipients and there is controversy as to whether the use…
2020 American Transplant Congress
Multiplicity of Non-HLA Targets for Antibodies Developed in Association with Ventricular Assist Device Implantation
M. Askar, D. Bhakta, H. Zafar, A. Alam, L. Pittmon, S. Kang, L. Klingman, J. Felius, S. M. Joseph, D. Wencker, D. M. Meyer, S. A. Hall
Baylor University Medical Center and Baylor Scott & White Research Institute, Dallas, TX
*Purpose: Multiple non-HLA antibodies have been implicated in poor outcomes after heart transplantation. Development of HLA and Non-HLA antibodies have been reported in association with…
2020 American Transplant Congress
Discovery and Validation of a Urinary Exosome mRNA Signature for the Diagnosis of Human Kidney Transplant Rejection
R. El Fekih¹, A. Alghamdi¹, J. Hurley², C. Coticchia², J. Choi¹, H. Allos¹, S. Eskandari¹, S. Bentink², V. Tadigotla², L. Riella¹, J. Markmann³, K. Safa³, R. Formica⁴, J. Skog², J. Azzi¹
¹Medecine, Brigham and Women's Hospital, Boston, MA, ²Exosome Diagnostics Inc., Waltham, MA, ³Massachusetts General Hospital, Boston, MA, ⁴Yale School of Medecine, New Haven, CT
*Purpose: Monitoring kidney transplant rejection by repeated biopsies might result in increased procedural complications and cost. Exosomes are nanometer-sized vesicles released by cells carrying trans…
2020 American Transplant Congress
Calculated Panel Reactive Antibody Values Increase for Kidney Transplant Candidates with HLA-DQA and HLA-DPB Unacceptable Antigens
E. P. Kransdorf¹, C. Murphey², M. Maiers³, L. Gragert⁴
¹Cedars-Sinai Heart Institute, Beverly Hills, CA, ²Immunogenetics Lab, Southwest Immunodiagnostics, Inc., San Antonio, TX, ³Bioinformatics Research, Be The Match/National Marrow Donor Program, Minneapolis, MN, ⁴Department of Pathology, Tulane University School of Medicine, New Orleans, LA
*Purpose: Calculated panel-reactive antibody (CPRA) is the official metric of sensitization used by the United Network for Organ Sharing (UNOS) for kidney allocation. CPRA includes…