Am J Transplant, Volume 20, Suppl 3 Archives - Page 23 of 223 - ATC Abstracts

2020 American Transplant Congress
Immune Cell Subset Profiles in HLA-Sensitized Kidney Transplant Patients (HS KTx Pts) Desensitized with Clazakizumab (CLZ, Humanized Anti-IL-6 Monoclonal Antibody) Followed by Transplantation (Tx)
S. Ge¹, M. Chu¹, A. D. Guzman¹, E. D. Ortiz¹, A. Vo², N. Ammerman², S. C. Jordan², M. Toyoda¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: IL-6, B cell growth factor, increases follicular T helper cell (Tfh) activity, promoting plasmablast (PB) and plasma cell (PC) differentiation, and antibody production. A…
2020 American Transplant Congress
De Novo Dosing and Trough Attainment Trends of Extended-Release Tacrolimus in the Absence of Dose Adjustments
M. J. Moritz¹, D. R. Stevens², U. Meier-Kriesche², T. A. Horwedel²
¹Department of Surgery, Lehigh Valley Health Network, Allentown, PA, ²Veloxis Pharmaceuticals, Cary, NC
*Purpose: Initial dosing of tacrolimus extended-release tablets (LCPT) was 0.17 mg/kg/day in the pivotal trial in de novo kidney transplant recipients. Dosing subsequent to the…
2020 American Transplant Congress
Liver Live Donor Champion: Advocacy Training to Facilitate Identification of Live Liver Donors
A. D. Love¹, L. R. Herbst¹, D. R. Helfer¹, L. Kurman², M. G. Bowring¹, S. R. Weeks¹, E. King¹, D. L. Segev¹, J. Garonzik Wang¹
¹Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, ²Surgery, The Johns Hopkins Hospital, Baltimore, MD
*Purpose: Although live donor liver transplantation (LDLT) may help address organ shortage, patients lack knowledge about living donation and are reluctant to speak to potential…
2020 American Transplant Congress
Liver Transplantation in Patients Requiring Pre-Transplant Mechanical Ventilation
T. Ito, A. Aziz, A. E. Murray, S. Younan, J. DiNorcia III, V. G. Agopian, H. Yersiz, D. G. Farmer, R. W. Busuttil, F. M. Kaldas
The Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Increasing transplant candidate acuity has resulted in more patients requiring perioperative intensive care and mechanical ventilation prior to liver transplantation (LT). However, studies on…
2020 American Transplant Congress
Bile Microbiology and Antibiotic Susceptibility in Liver Transplant Recipients versus Non-Transplant Population
S. Suh, Y. Choi
Surgery, Chung-Ang University Hospital, Seoul, Korea, Republic of
*Purpose: The signs and symptoms of biliary infection in liver transplantation (LT) recipients are frequently subtle because of immunosuppression, thereby delaying its diagnosis and increasing…
2020 American Transplant Congress
Pharmacist Management after Preemptive Monitoring Conversion as a Component of a Cytomegalovirus Antiviral Stewardship Program at a Large Transplant Center
C. Wong, M. Jorgenson, J. Descourouez, K. Goldrosen, C. Saddler, J. Smith, D. Mandelbrot
UW Health, Madison, WI
*Purpose: Cytomegalovirus (CMV) in solid organ transplant (SOT) is associated with negative graft and patient outcomes. Prophylactic agents of choice have substantial cytotoxicity, and patients…
2020 American Transplant Congress
Polyoma Virus Infection in Renal Transplant Recipients Using Tacrolimo and Everolimo
P. M. Souza¹, C. Ribeiro¹, S. C. Miranda¹, A. S. Alvarenga¹, C. R. Felipe¹, G. Marques¹, G. P. Tarcia¹, L. L. Braga², L. S. Ferreira Boy², M. L. Martins²
¹Nephrology, Santa Casa de Belo Horizonte, Belo Horizonte, Brazil, ²Scientific Technical Development Management, Hemominas Foundation, Belo Horizonte, Brazil
*Purpose: Seropositivity for polyoma virus can reach 80% in kidney transplant recipients, with 1 to 10% polyoma associated nephropathy which negatively influences graft survival. Therefore,…
2020 American Transplant Congress
Developing a Patient Specific Search of Heart Transplant Programs: Feedback from Heart Transplant Candidates and Recipients
W. T. McKinney¹, M. J. Bruin², C. R. Schaffhausen¹, S. Chu², J. Synder³, C. M. Martin⁴, T. Alexy⁴, B. L. Kasiske⁵, A. K. Israni¹
¹Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, ²College of Design, University of Minnesota, Minneapolis, MN, ³Hennepin Healthcare Research Institute, Minneapolis, MN, ⁴Cardiology Division, University of Minnesota Department of Medicine, Minneapolis, MN, ⁵Department of Medicine, Hennepin Healthcare, Minneapolis, MN
*Purpose: Patients seeking a heart transplant must contemplate numerous factors when making decisions regarding their care. Waitlist acceptance criteria, donor acceptance practices and outcomes often…
2020 American Transplant Congress
The Histological Picture of Indication Biopsies in the First Days after Renal Transplantation
E. Van Loon, M. Coemans, A. Senev, D. Kuypers, M. Emonds, M. Naesens
Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
*Purpose: In preclinical studies, ischemia reperfusion injury and older donor age are associated with renal inflammation in the early phase after transplantation. In human kidney…
2020 American Transplant Congress
Stem Cell and Novel Neurotrophic Factors to Promote Functional Outcomes in Limb Transplantation
S. K. Salgar, J. Weiss, C. Phillips, E. Malin, V. Gorantla, J. Harding
Clinical Investigation, Madigan Army Medical Center, Tacoma, WA
*Purpose: Recently, transplantation of hand and face has become a new clinical specialty. The objective of this study was to determine whether adult Mesenchymal Stem…