Am J Transplant, Volume 20, Suppl 3 Archives - Page 218 of 223 - ATC Abstracts

2020 American Transplant Congress
Hyperammonemia Syndrome in a Kidney Transplant Recipient Caused by Quinolone-Resistant Ureaplasma Infection
A. B. Higgins¹, R. Rogers², A. J. Osband³, R. Gohh⁴, P. Morrissey³, A. Seo¹, B. Chen¹, D. Crabb⁵, S. Leal⁵, K. Waites⁵, D. Farmakiotis², G. J. Nau²
¹Department of Medicine, Alpert Medical School of Brown University, Providence, RI, ²Division of Infectious Diseases, Alpert Medical School of Brown University, Providence, RI, ³Department of Surgery, Alpert Medical School of Brown University, Providence, RI, ⁴Division of Nephrology, Alpert Medical School of Brown University, Providence, RI, ⁵Division of Laboratory Medicine, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Urease-producing bacteria release significant amounts of ammonia. Donor-derived Ureaplasma infections in lung transplant recipients have been implicated in the pathogenesis of hyperammonemia syndrome (HS).…
2020 American Transplant Congress
Kidney Transplant Recipients with De Novo Donor Specific Antibody is Associated with Increased Risk of Developing BK Viremia
S. Kareem¹, L. Suresh², A. Gundroo¹, J. Von Viger¹, S. Chang¹
¹Internal Medicine, University of Buffalo, Buffalo, NY, ²Pathology, University of Buffalo, Buffalo, NY
*Purpose: Background: De novo donor specific anti-HLA antibodies (dnDSA) has profound effect on the renal graft long-term function and survival. Studies has shown identifications of…
2020 American Transplant Congress
Monitoring Recipients of Public Health Service (PHS) Increased Risk Donors Using an Electronic Medical Record-Based System
M. Malinis¹, B. Nuesse², S. Carter², S. Emre¹, R. Formica¹, S. Kulkarni¹, D. Mulligan¹, M. Schilsky¹, M. M. Azar¹
¹Yale School of Medicine, New Haven, CT, ²Yale New Haven Health, New Haven, CT
*Purpose: In 2014, the Organ Procurement and Transplantation Network (OPTN) policy was updated, mandating transplant centers to implement a post-transplant screening protocol for transmissible diseases.…
2020 American Transplant Congress
Can Autologous Islet Cell Transplant Be a Comparable Choice to Parenchymal Preserving Surgery for Patients with Chronic Pancreatitis with Respect to Glycemic Control?
B. M. Williams, X. Baldwin, J. S. Vonderau, M. Hanson, C. S. Desai
University of North Carolina, Chapel Hill, NC
*Purpose: The aim of this study is to examine the difference in glycemic outcomes between total pancreatectomy and autologous islet cell transplant (TPAIT) and parenchymal…
2020 American Transplant Congress
Cervical Total Arterial Anastomosis Mouse-to-Rat Heterotopic Heart Xenotransplantation
A. Ren, Z. Li, X. Zhang, R. Deng, Y. Ma
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Xenotransplantation is an effective way to solve the problem of donor shortage. However, clinical use of xenotransplantation is currently limited due to immunological challenges.…
2020 American Transplant Congress
Anticipated Observations: The Role of DQ Antigen Frequencies among Donors and Recipients in a Pediatric Renal Transplant Cohort
S. Gattis¹, R. George², R. Liverman³, A. Serluco³, R. Garro², J. Figueroa², R. A. Bray², H. M. Gebel², H. C. Sullivan²
¹Emory Healthcare, Atlanta, GA, ²Emory University School of Medicine, Atlanta, GA, ³Children's Healthcare of Atlanta, Atlanta, GA
*Purpose: Donor specific HLA antibodies (DSA) that develop in the face of donor-recipient HLA mismatches are well-established independent predictors of graft loss in solid organ…
2020 American Transplant Congress
Utilization of Kidneys with Microthrombi and Acute Kidney Injury
W. De Faria, E. Shipman, G. Ciancio, G. Guerra
Miami Transplant Institute, Miami, FL
*Purpose: Kidneys continue to be discarded for reasons such as surgical damage, high kidney donor profile index (KDPI), prolonged cold ischemia time, and acute kidney…
2020 American Transplant Congress
Donor-Specific B Cell Frequency Assessed by a Novel Multiplex Bead-Based Assay Predicts Graft Failure in Kidney Transplant Recipients
Z. Ilyas, A. Akl, D. Pinelli, L. Gallon, A. R. Tambur, M. Ansari
Northwestern University Feinberg School of Medicine, Chicago, IL
*Purpose: Kidney transplant recipients with sensitization to HLA defined by a high percentage of Panel Reactive Antibodies (PRA) or Donor-specific anti-HLA antibodies (DSA) are at…
2020 American Transplant Congress
The Transcriptomic Analysis Revealed a Clear Deregulation of the C1QB Gene in Peripheral Blood Mononuclear Cells of Renal Transplant Patients with Chronic Antibody Mediated Rejection
G. Zaza¹, S. Granata¹, G. Santoro¹, C. Caletti¹, P. Pontrelli², F. Rascio³, M. Rossi¹, S. Andrighetto¹, G. Grandaliano⁴
¹Department of Medicine, Renal Unit, University/Hospital of Verona, Verona, Italy, ²Department of Emergency and Organ Transplantation-Nephrology Unit, University of Bari, Bari, Italy, ³Nephrology, Dialysis and Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy, ⁴Università Cattolica del Sacro Cuore, Roma, Italy
*Purpose: Chronic antibody-mediated rejection (CAMR) is a multi-factorial pathological condition that can affect more that 40-50% of kidney transplanted recipients. Its clinical evolution is often…
2020 American Transplant Congress
Effector Differentiation of Endogenous Antigen-Specific CD8⁺ T Cells is Selectively Limited by CTLA-4 Ig
S. M. Krummey, K. P. Tong, M. L. Ford
Emory Transplant Center, Emory University School of Medicine, Atlanta, GA
*Purpose: Costimulation blockade with belatacept (CTLA-4 Ig) offers improved renal function and reduced toxicity following transplantation compared to calcineurin inhibitors. Nonetheless, episodes of acute T…