ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Assessment of Coronary Allograft Vasculopathy by Intravascular Ultrasound 6 Weeks and One Year after Heart Transplantation: A Single Center Study

    A. Alam, E. Dib, H. Zafar, J. Felius, S. Hall, S. Joseph

    Cardiology, Baylor University Medical Center, Dallas, TX

    *Purpose: Coronary allograft vasculopathy (CAV) continues to be a common cause of morbidity and mortality in heart transplant recipients. Little is known about the timing…
  • 2020 American Transplant Congress

    Impact of the 2015 LAS Revisions on Lung Candidates with Pulmonary Vascular Disease

    K. Lindblad1, R. Goff1, K. Chan2

    1UNOS, Richmond, VA, 2University of Michigan, Ann Arbor, MI

    *Purpose: On February 19, 2015 a major revision to the Lung Allocation Score (LAS) was implemented with the goal of more accurately reflecting waitlist urgency…
  • 2020 American Transplant Congress

    Acute Kidney Injury And Chronic Kidney Disease After Lung Transplantation: Incidence And Risk Factors In A Large Single-center Cohort

    D. Abdelwahab, R. Marron, Z. Choudhry, I. Lee, J. Wu, J. Brown

    Lewis Katz School of Medicine, Temple University, Philadelphia, PA

    *Purpose: Chronic kidney disease (CKD) is a common complication after lung transplant. The reported incidence in small studies varies ranges from10-90%. Furthermore, data on risk…
  • 2020 American Transplant Congress

    The Art Rather Than the Science of Non-HLA Antibody Mediated Rejection in Heart Transplantation: A Single Center Experience

    A. Alam, S. Mckean, R. Patel, V. Darst, H. Zafar, C. Guerrero, M. Askar, T. Sam, S. Hall

    Cardiology, Baylor University Medical Center, Dallas, TX

    *Purpose: The role of non-HLA antibodies (Ab) in HLA-DSA negative antibody mediated rejection (AMR) following heart transplant (HTx) remains largely unknown.*Methods: Retrospective analysis of all…
  • 2020 American Transplant Congress

    TGR5/Cathepsin E Signaling Regulates Macrophage Innate Immune Activation in the Sterile Inflammatory Liver Injury

    H. Zhou, S. Zhou, Q. Wang, Z. Rao, X. Wang, L. Lu

    The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    *Purpose: The hepatic proinflammatory response represents a major cause of liver ischemia and reperfusion (IR) injury. Although the role of plasma membrane-bound G protein-coupled bile…
  • 2020 American Transplant Congress

    Withaferin A Prolongs Islet Allograft Survival in a Mouse Transplant Model by Preventing T Lymphocyte Proliferation and Dendritic Cell Maturation

    K. Kumano1, M. A. Kanak2, S. Vasu1, Y. Liu1, M. Lawrence1, B. Naziruddin1

    1Baylor University Medical Ctr, Dallas, TX, 2Virginial Commonwealth University Medical Center, Richmond, VA

    *Purpose: Chronic decline in islet graft function and toxicities imposed by immunosuppressant drugs remain as challenges to the widespread use of islet transplantation for type…
  • 2020 American Transplant Congress

    Next Generation Sequencing Based Analysis of the T-Cell Receptor Repertoire Reveals an Increase of Alloreactive T-Cell Clones after Kidney Transplantation

    C. Aschauer1, K. Jelencsics1, K. Hu1, R. Reindl-Schwaighofer1, J. Vetter2, A. Heinzel1, A. Kainz1, G. Gualdoni1, S. Schaller2, S. Winkler2, R. Oberbauer1

    1Department of Medicine III - Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria, 2Bioinformatics Research Group, University of Applied Sciences Upper Austria, Hagenberg im Muehlkreis, Austria

    *Purpose: The development of the alloreactive T-cell repertoire after kidney transplantation (KTX) is not yet fully understood. The combination of mixed lymphocyte reaction (MLR) and…
  • 2020 American Transplant Congress

    Comparing Early Kidney after Liver Transplant (KALT) and Simultaneous Liver-Kidney Transplant (SLK): Evaluating Racial Disparities. Will Everyone Have the Same “Safety Net”?

    C. Jay1, R. Stratta1, W. Washburn2, J. Rogers1, S. Rudnick1, A. Reeves-Daniel1, J. Heimbach3

    1Wake Forest Baptist Health, Winston-Salem, NC, 2The Ohio State University Wexner Medical Center, Columbus, OH, 3Wake Forest Baptist Health, Winston-Salem, MN

    *Purpose: In 2017, UNOS implemented simultaneous liver-kidney transplant (SLK) guidelines that included medical eligibility criteria and a “safety net” providing prioritization on the kidney transplant…
  • 2020 American Transplant Congress

    Does the Distance from the Transplant Center Impact Kidney Transplant (KT) DGF, CIT and Outcomes?

    M. Laftavi1, O. Pankewycz2, R. Shahbazov1, A. Almonte1, B. Gallay2, J. Leggat2, R. Hod Dvorai1, C. Hubbell1, S. Narsipur2

    1Transplant, Upstate Medical University, SYRACUSE, NY, 2Nephrology, Upstate Medical University, SYRACUSE, NY

    *Purpose: Currently, there is an ongoing debate regarding the efficient use of available organs (utility) versus the fair access to transplant (equity). UNOS is now…
  • 2020 American Transplant Congress

    Impact of Kidney Donor Profile Index (KDPI) on Long-Term Outcomes in Deceased Donor Renal Transplant Recipients with Donor Acute Kidney Injury

    A. Brar1, M. Salifu2, D. Adey1, A. Gruessner2

    1University of California, San Francisco, San Francisco, CA, 2SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Kidneys with donor acute kidney injury (AKI) are discarded at a higher rate. The purpose of the study is to assess long term renal…
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