Am J Transplant, Volume 20, Suppl 3 Archives - Page 202 of 223 - ATC Abstracts

2020 American Transplant Congress
Combining New Biomarkers: Donor Derived Cell Free DNA (dd-cfDNA) and Transcriptomics Impacts Rejection Diagnosis, Treatment and Follow Up
S. Anand, L. Dong, D. Miller, I. Lloyd, D. Morris, T. Srinivas
Intermountain Medical Center, Murray, UT
*Purpose: Transcriptomics (Tr) is an emerging adjunct to traditional histological diagnosis (HDx) for kidney allograft rejection (KAR). We describe our experience of using Tr and…
2020 American Transplant Congress
Evolution of Molecular MMDx Scores after Kidney Transplantationin Different Donor Categories
P. Hruba¹, K. S. Madill-Thomsen², M. Mackova², J. Maluskova³, E. Honsova³, J. Slatinska⁴, P. F. Halloran², O. Viklicky⁴
¹Transplant Laboratory, IKEM, Prague, Czech Republic, ²ATAGC, University of Alberta, Edmonton, AB, Canada, ³Department of Pathology, IKEM, Prague, Czech Republic, ⁴Department of Nephrology, IKEM, Prague, Czech Republic
*Purpose: The outcome of kidney transplantation is highly affected by donor category. Little is known about molecular processes which may underline this phenomenon.*Methods: Using Molecular…
2020 American Transplant Congress
Graft Perfusion with an Hsp90 Inhibitor Prolongs Graft Survival in Murine Heart Transplantation by Modulating Expression of Cyclin-Dependent Kinases and the Senolytic Effect
T. Tanaka, T. Maehana, N. Masumori
Department of Urology, Sapporo Medical University, Sapporo, Japan
*Purpose: We have previously demonstrated that administration of alvespimycin, a heat shock protein 90 (HSP90) inhibitor, prolongs the allograft survival in murine skin and heart…
2020 American Transplant Congress
The Prevalence of Preemptive Transplantation at a Large Volume Kidney Transplant Center
T. Menser¹, M. J. Hobeika², S. G. Yi², T. Nisar¹, A. Gaber²
¹Houston Methodist Research Institute, Houston, TX, ²Houston Methodist Hospital, Houston, TX
*Purpose: In the wake of the Executive Order on Advancing American Kidney Health, it is essential to fully examine the current care paradigm for chronic…
2020 American Transplant Congress
Outcome of Trans-Umbilical Single Port Laparoscopic Donor Nephrectomy
D. Lia, Y. Alsalmay, L. Teperman, E. Grodstein, L. Lau, E. Molmenti, A. Fahmy
Surgery, Northshore-LIJ, Manhasset, NY
*Purpose: To evaluate the safety, efficacy, and outcomes of trans-umbilical single port laparoscopic donor nephrectomy (SPLDN).*Methods: We performed a retrospective review of 100 SPLDNs between…
2020 American Transplant Congress
Organ Offer Behavioral Research Enhances Transplant Surgeon Training
T. S. Diwan¹, D. Stewart², K. Lindblad², A. Dick³, R. Hirose⁴, L. Ratner⁵
¹Univ of Cincinnati Med Ctr, Cincinnati, OH, ²United Network for Organ Sharing, Richmond, VA, ³Seattle Children's Hospital, Seattle, WA, ⁴UCSF Health, San Francisco, CA, ⁵Columbia Univ/NY Pres Hosp, New York, NY
*Purpose: Due to the complexities of fielding organ offers, the 2019 ASTS 2nd Year Surgical Fellows Symposium’s agenda included multiple sessions devoted to training on…
2020 American Transplant Congress
Efficacy and Safety Outcomes by Donor Type in De Novo Renal Transplant Recipients Receiving Everolimus with Reduced-Dose Calcineurin Inhibitor: 24-Month Results from Transform
S. Berger¹, M. Bakr¹, F. Bemelman¹, R. Danguilan¹, H. De Fijter¹, D. Han¹, M. Kim¹, E. Mor¹, A. Patel¹, M. Hernandez Gutierrez², A. Gawai², Y. Watarai¹
¹TRANSFORM Study Group, Basel, Switzerland, ²Novartis Pharma AG, Basel, Switzerland
*Purpose: To assess the efficacy and safety outcomes in de novo renal transplant (RTx) recipients receiving everolimus with reduced-exposure calcineurin inhibitor (EVR+rCNI) versus mycophenolate with…
2020 American Transplant Congress
Chronic Active T-Cell Mediated Rejection is Variably Responsive to Immunosuppressive Therapy
V. Kung¹, M. Haas¹, M. Gillespie², E. Huang², R. Sandhu²
¹Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Chronic active T cell-mediated rejection (CACMR) is a newly described variant of kidney allograft rejection associated with long-term graft loss. A key histologic feature…
2020 American Transplant Congress
Simultaneous Laparoscopic Bilateral Native Nephrectomy and Open Kidney Transplantation in Patients with ESRD Due to ADPKD: A Single Center Experience
N. Abrol, A. Bentall, V. Torres, M. Prieto
Mayo Clinic, Rochester, MN
*Purpose: Patients with Autosomal Dominant Polycystic Kidney (ADPKD) progressing to end-stage renal disease (ESRD) often are symptomatic due to cystic kidneys and require surgical intervention.…
2020 American Transplant Congress
Effect of Simultaneous Presence of Anti-Blood Group A/B and -HLA Antibodies on Clinical Outcomes in Kidney Transplantation Across Positive Crossmatch: A Nationwide Cohort Study
H. Kwon, Y. Ko, D. Han
Department of General Surgery, Asan Medical Center, Seoul, Korea, Republic of
*Purpose: ABO-incompatible (ABOi) and positive crossmatch (XM) kidney transplantation (KT) have been considered immunologically challenging. The present study analyzed the clinical outcomes in XM positive…