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American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Early Impact of Interleukin-6 Blockade on the Distribution of Peripheral Blood Immune Cell Subpopulations – 3-Month Results of a Phase 2 Trial Evaluating Clazakizumab in Late Antibody-Mediated Rejection

    K. A. Doberer1, G. A. Boehmig1, M. Streitz2, S. Schlickeiser2, F. Bauernfeind1, A. Spittler3, B. Jilma4, F. Eskandary1, E. Chong5, S. Schranz4, K. Budde6, M. Dürr6

    1Department of Medicine III, Medical University of Vienna, Vienna, Austria, 2Charité Universitätsmedizin Berlin, Institute of Medical Immunology, Berlin, Germany, 3Center of Translational Research, Medical University of Vienna, Vienna, Austria, 4Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria, 5Vitaeris Inc., Vancouver, BC, Canada, 6Division of Nephrology and Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany

    *Purpose: Interleukin-6 (IL-6) is considered to play a critical role within the multifacted pathophysiological process of antibody-mediated rejection (ABMR), including modulation of regulatory T cells…
  • 2020 American Transplant Congress

    A Single Nucleotide Polymorphism of Tweak Predicts Arterio- and Arteriolohyalinosis in Kidney Transplants and is Associated with Allograft Survival

    A. Karolin1, D. Thottan1, J. Zinsli1, S. Rudloff1, U. Huynh-Do1, V. Banz2, T. Berney3, M. Pascual4, T. Müller5, P. d’Amico6, I. Binet7, D. Sidler1

    1Nephrology and Hypertension, University Bern, Bern, Switzerland, 2University Bern, Bern, Switzerland, 3University Hospital Genevia, Genevia, Switzerland, 4University Hospital Lausanne, Lausanne, Switzerland, 5University Hospital Zurich, Zurich, Switzerland, 6Hospital St.Gallen, St.Gallen, Switzerland, 7University Hospital Basel, Basel, Switzerland

    *Purpose: We have recently demonstrated that the TNF superfamily member is critical for the pathogenesis of Calcineurin Inhibitor Toxicity (CNT). CNT is a common side…
  • 2020 American Transplant Congress

    Late Conversion from Calcineurin Inhibitors to Belatacept in Kidney-Transplant Recipients Has a Significant Beneficial Impact on Glycemic Parameters

    J. Noble, F. Terrec, T. Jouve, H. Neciri Bennani, P. Benhamou, P. Malvezzi, B. Janbon, D. Giovannini, L. Rostaing

    Nephrology and Transplant Unit, CHU Grenoble, Grenoble, France

    *Purpose: Calcineurin inhibitors (CNIs) and steroids are strongly associated with new-onset diabetes after transplantation (NODAT), worsening of pre-existing diabetes, and cardiovascular events. We assessed the…
  • 2020 American Transplant Congress

    The Link between Waitlist Mortality and Access to Transplant, an Imaginative Reality

    R. Batra1, D. Mulligan1, D. Haakinson1, S. Noreen2, D. Stewart2, G. Gan3, Y. Deng3, S. Kulkarni1

    1Surgery, Yale University School of Medicine, New Haven, CT, 2UNOS, Richmond, VA, 3Yale University, New Haven, CT

    *Purpose: Liver transplant waitlist mortality due to inadequate access to livers is the Achilles heel in liver transplantation in United States. This remains amongst the…
  • 2020 American Transplant Congress

    Efficacy & Safety of Once Daily Tacrolimus Compared to Twice Daily Tacrolimus after Liver Transplantation

    K. Bzeizi, A. Albenmousa, M. Shawkat, W. Alhamoudi, S. Alabad, R. Troisi, D. Broering

    KFSHRC, Riyadh, Saudi Arabia

    *Purpose: To compare the efficacy and safety of once daily prolonged release tacrolimus compared to twice daily tacrolimus in liver transplantation patients*Methods: Medline, EMBASE, CENTRAL…
  • 2020 American Transplant Congress

    Impact of Patent Foramen Ovale on Post Liver Transplant Neurological Outcomes

    S. Naffouj, F. Nimri, M. Mohammed, E. Abu-Asala, L. Al-khatib, M. Abu-Ghanimeh, D. Venkat

    Henry Ford Hospital, Detroit, MI

    *Purpose: The presence of patent foramen ovale (PFO) can result in intra-cardiac shunting of atheromatous debris during liver transplantation (LT) given the acute hemodynamic changes…
  • 2020 American Transplant Congress

    Because That is Not How The Hierarchy Works: Primary Care Provider Perspectives on Liver Transplant Referral and Access to Transplant

    V. Madabhushi1, A. Murphy2, C. Reams3, R. Gedaly3, M. Shah3, N. Pope4, M. Gupta5

    1General Surgery, University of Kentucky, Lexington, KY, 2University of Kentucky, College of Medicine, Lexington, KY, 3Surgery, DIvision of Transplant Surgery, University of Kentucky, Lexington, KY, 4University of Kentucky, College of Social Work, Lexington, KY, 5Surgery, Division of Transplant Surgery, University of Kentucky, Lexington, KY

    *Purpose: In rural America, the road to obtaining a liver transplant (LTX) often starts at the primary care provider’s (PCP) office. Patients in rural communities…
  • 2020 American Transplant Congress

    Risk Factors for Bacterial or Candidal Donor-Derived Infections among Solid Organ Transplant Recipients

    J. A. Anesi1, E. Lautenbach1, J. H. Han2, D. H. Lee3, H. Clauss4, R. Hasz5, E. Molnar4, D. Alimenti1, A. R. Motzer4, S. West5, W. B. Bilker1, P. Tolomeo1, E. A. Blumberg1, T. Prevention Epicenters Program6

    1University of Pennsylvania, Philadelphia, PA, 2GlaxoSmithKline, Rockville, MD, 3Drexel University, Philadelphia, PA, 4Temple University, Philadelphia, PA, 5Gift of Life Donor Program, Philadelphia, PA, 6Centers for Disease Control and Prevention, Atlanta, GA

    *Purpose: Donor-derived infections (DDIs) among solid organ transplant recipients (SOTR) are often associated with significant morbidity and mortality, although the predisposing factors for DDIs remain…
  • 2020 American Transplant Congress

    Transplantation from Donors with Positive Blood Culture

    H. Mo, S. Min, H. Ko, C. Chung, H. Kim, A. Han, J. Ha

    Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of

    *Purpose: The use of organs from donors with infection is limited because of the possibility of transmission. Herein we report our experience of transplantation from…
  • 2020 American Transplant Congress

    Kidney Transplantation after Multiple Myeloma: The Last 2 Decades

    V. Nair, K. Jhaveri, M. Abate

    Medicine, Northwell Health, Manhasset, NY

    *Purpose: Due to recent advances, patients with a history of multiple myeloma (MM) and ESKD are more frequently offered kidney transplantation (Ktx). Existing literature does…
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