Am J Transplant, Volume 20, Suppl 3 Archives - Page 174 of 223 - ATC Abstracts

2020 American Transplant Congress
Donor-Derived Cell-Free DNA Combined with Histology Improves Prediction of eGFR Decline in Kidney Transplant Recipients over Histology Alone
M. Gillespie, M. Haas, K. Lim, A. Vo, A. Peng, R. Najjar, S. Sethi, S. Jordan, E. Huang
Cedars-Sinai, Los Angeles, CA
*Purpose: Higher Banff inflammation and chronicity scores on kidney transplant (KTx) biopsies (Bx) have been associated with poorer graft survival, but Bx scores alone imperfectly…
2020 American Transplant Congress
Hif-1a Expression Influences Recipient Clinical Outcomes in Liver Transplant Patients
K. Kadono, T. Ito, H. Kojima, K. Nakamura, H. Hirao, S. Kageyama, K. J. Dery, A. Murray, R. W. Busutill, F. Kaldas, J. W. Kupiec-Weglinski
Liver Transplant Surgery, UCLA, Los Angeles, CA
*Purpose: Liver ischemia-reperfusion injury (IRI), an innate-immune dominated hepatocellular damage, is a risk factor for early allograft dysfunction (EAD) and rejection crises in liver transplantation…
2020 American Transplant Congress
T-cell Receptor Deep Sequencing to Distinguish Autoimmune Recurrence from Allograft Rejection in Liver Transplant Patients with Autoimmune Liver Disease
K. J. Yang¹, M. Martinez², B. Shonts¹, C. A. Parks¹, A. Z. Obradovic¹, T. M. Savage¹, E. Spyrou¹, S. Lau¹, M. I. Colquhoun¹, K. Rodgers¹, E. Verna³, S. M. Coley⁴, S. Yang¹, Y. Shen⁵, M. Sykes¹
¹Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY, ²Department of Pediatrics, Columbia University, New York, NY, ³Department of Medicine, Columbia University, New York, NY, ⁴Department of Pathology, Columbia University, New York, NY, ⁵Center for Computational Biology & Bioinformatics, Department of Systems Biology, Columbia University, New York, NY
*Purpose: Patients who undergo liver transplantation for autoimmune liver disease (ALD) experience high rates of graft failure. The relative roles of recurrent ALD and rejection…
2020 American Transplant Congress
Belatacept Combined with BTLA Prolong Allogeneic Kidney Graft Survival and Inhibited Acute Rejection after Kidney Transplantation
H. Zhang, Z. Wang, J. Zhang, Z. Han, J. Tao, H. Chen, L. Sun, R. Tan, M. Gu
Jiangsu Province Hospital, Nanjing, China
*Purpose: Belatacept as a high-affinity variant of CTLA-4Ig, has been applied into kidney transplantation to against acute rejection. However, adoption of Belatacept has been limited…
2020 American Transplant Congress
Real-Time Viability Assessment During Normothermic Machine Perfusion with Resonance Raman Spectroscopy
R. J. De Vries¹, S. Raigani¹, P. Romfh², S. E. Cronin¹, C. A. Pendexter¹, C. Carroll¹, T. M. Van Gulik³, P. Chen², K. Uygun¹, H. Yeh¹, S. N. Tessier¹
¹Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, ²Pendar Technologies, Cambridge, MA, ³Surgery, Amsterdam University Medidical Centers, Location AMC, Amsterdam, Netherlands
*Purpose: Viability assessment during normothermic machine perfusion (NMP) continues to lack objective metrics that facilitate accurate clinical decision making, in order to minimize discard rates…
2020 American Transplant Congress
Humoral Sensitization Overrides Pregnancy-Induced T Cell Transplantation Tolerance
D. Tran¹, A. Suah¹, S. Khiew¹, J. Young¹, M. Andrade¹, J. Pollard¹, Q. Wang¹, D. Yin¹, G. Chalasani², M. Alegre¹, A. Chong¹
¹Department of General Surgery, University of Chicago, Chicago, IL, ²Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA
*Purpose: There are ample clinical data that a major long-term consequence of pregnancy is humoral allosensitization. Paradoxically, pregnancy is also a state of spontaneous allogeneic…
2020 American Transplant Congress
Long Term Outcomes of Hypertensive Kidney Donors
H. Ibrahim, S. Hebert, H. E. Adrogue, D. T. Nguyen, E. A. Graviss, A. Gaber, A. Matas
Houston Methodist Hospital, Houston, TX
*Purpose: Many people with hypertension are excluded from kidney donation fearing that hypertension is a major cause of CKD and its impact maybe magnified after…
2020 American Transplant Congress
One Organ Procurement Organization Coordinates 43% of All Uncontrolled Donation after Circulatory Determination of Death Donors Recovered in the United States Over 24 Years
R. D. Hasz, S. M. West, H. M. Nathan
Gift of Life Donor Program, Philadelphia, PA
*Purpose: An IOM report published in 2006 estimated that 22,000 potential uncontrolled Donation after Circulatory Determination of Death (uDCDD) donors die each year in the…
2020 American Transplant Congress
Association between Area-Level Measures of Deprivation and Readiness to Pursue Living Donor Kidney Transplant
M. A. Saqib, A. Li, J. Hussain, Q. Wang, N. El-Dassouki, A. Dychiao, L. Angarso, N. Edwards, M. Novak, I. Mucsi
University Health Network, Toronto, ON, Canada
*Purpose: This study aims to assess if material deprivation is associated with readiness to pursue living donor kidney transplant (LDKT)*Methods: A cross-sectional sample of adults…
2020 American Transplant Congress
Determinants of Cardiovascular Benefit Observed in a Population with a Functioning Renal Transplant versus Patients Undergoing Chronic Dialysis
J. Sleiman, C. Castellaro, G. Laham, M. Schiavone, M. Biain, L. Brukman, G. Soler Pujol, C. Diaz
Nephrology, CEMIC, Caba, Argentina
*Purpose: Patients (pts) with end stage renal disease have a high morbidity and mortality rate, mostly due to cardiovascular events (CV). Transplantation (Tx) improves survival…