Am J Transplant, Volume 20, Suppl 3 Archives - Page 144 of 223 - ATC Abstracts

2020 American Transplant Congress
Dissecting Humoral Alloimmune Sensitization: A Dynamic Interplay of Different Cellular Compartments
A. Torija, A. Favà, E. Crespo, M. Jarque, M. Meneghini, N. Bolaños, J. Grinyo, O. Bestard
Kidney transplantation Unit, Bellvitge University Hospital- IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain
*Purpose: Humoral alloimmune memory is the main barrier for successful transplantation and is generated by a complex and compartmentalized B-cell immune response. Understanding the role…
2020 American Transplant Congress
Cmv Infection Sensitizes Transplant Recipients by Promoting Alloreactive T Cell Response
S. Yu, A. Dangi, X. Luo
Nephrology/Medicine, Duke University, Durham, NC
*Purpose: Cytomegalovirus (CMV) infection has been associated with allograft rejection in immunosuppressed transplant recipients. We have previously shown that acute CMV infection impairs the induction…
2020 American Transplant Congress
A Novel Polymer Product, APP-103, Reduces IRI-Induced Damage and Promotes Functional Improvement in Syngeneic Models of Renal Transplantation
K. Minami¹, S. Bae², H. Uehara¹, J. Iske¹, J. Reder³, H. Azuma⁴, A. Weins¹, E. Van Keuren⁵, B. Houser³, A. El-Khal¹, P. Kang², S. Tullius¹
¹Brigham and Women's Hospital, Boston, MA, ²Beth Israel Deaconess Medical Center, Boston, MA, ³Celdara Medical, Lebanon, NH, ⁴Osaka Medical College, Osaka, Japan, ⁵Georgetown University, Washington DC, DC
*Purpose: Our data introduce APP-103 as a novel, non-toxic and site-activating therapeutic approach that effectively ameliorates the consequences of ischemia/reperfusion injury in solid organ transplantation.*Methods:…
2020 American Transplant Congress
Hemodialysis (HD) Treatment Associates with Increased Risk of Delayed Graft Function (DGF) after Renal Transplantation (RT) and Augmented Cd4 and Cd8 T Cell Proliferation Compared to Peritoneal Dialysis (PD)
A. Angeletti¹, C. Donadei¹, G. Donati¹, G. Di Certo¹, D. Conte¹, L. Gasperoni¹, E. Pelizzaro¹, C. Guglielmo¹, G. Comai¹, P. Cravedi², G. La Manna¹
¹DIMES, S.Orsola-Malpighi Hospital, Bologna University, Bologna, Italy, ²DIMES, Icahn School of Medicine at Mount Sinai, New York, NY, US, New York, NY
*Purpose: Delayed graft function (DGF) is a common event after RT that increases the risk of acute rejection and early graft loss. The impact of…
2020 American Transplant Congress
Molecular Phenotypes of Liver Transplant Injury: The INTERLIVER Study
K. S. Madill-Thomsen¹, P. F. Halloran¹, &. the INTERLIVER Study Group²
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²., ., AB, Canada
*Purpose: Liver parenchymal injury phenotypes are difficult to evaluate by histology but could be amenable to molecular assessment. Having developed a Molecular Microscope® Diagnostic System…
2020 American Transplant Congress
The Impact of Multi-Organ Transplant Allocation Priority on Wait-Listed Isolated Kidney Transplant Candidates
S. Westphal¹, E. Langewisch¹, A. Robinson², A. Wilk², T. Plumb¹, R. Mullane¹, S. Merani¹, A. Hoffman¹, A. Maskin¹, C. Miles¹
¹University of Nebraska Medical Center, Omaha, NE, ²United Network for Organ Sharing, Richmond, VA
*Purpose: Multi-Organ Transplant (MOT) candidates involving a kidney receive higher allocation priority than kidney alone transplant (KAT) candidates. The increasing utilization of MOT has the…
2020 American Transplant Congress
High Volume, Highly Efficient, Outcome- Centric KPD Program: A Single Center Experience with Direct Exchange Based Strategies
K. Al Meshari, D. Broering, I. Alahmadi, S. Raza, T. Ali, A. Alabbassi, H. Alahdal, F. Alzayer
King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia
*Purpose: We report our three and a half year experience with direct exchange (loop) based strategy single center KPD program.*Methods: 1. Inclusion of HLA and…
2020 American Transplant Congress
Frailty is Strongly Associated with Self-Reported Symptom Burden among Patients with Cirrhosis Undergoing Evaluation for Liver Transplantation
L. X. Deng, K. E. Bischoff, D. S. Kent, D. L. O’Riordan, S. Z. Pantilat, J. C. Lai
University of California, San Francisco, San Francisco, CA
*Purpose: Among patients with cirrhosis, frailty has most commonly been measured using instruments that focus on malnutrition, muscle wasting, and functional impairment. Little is known…
2020 American Transplant Congress
Comparison of Oropharyngeal Candidiasis Outcomes in Renal Transplant Recipients Receiving Nystatin or No Antifungal Prophylaxis
T. Q. Ky, L. Cotiguala, L. Fitzgerald, K. McMurry, J. Park, S. Tischer
Pharmacy, University of Michigan, Michigan Medicine, Ann Arbor, MI
*Purpose: Oropharyngeal candidiasis (OC) rate in the absence of antifungal prophylaxis has been reported as low as 7.4% after renal transplant. Due to perceived low…
2020 American Transplant Congress
The Liver Protects All? Donor Specific Antibody Formation in Heart-Liver Transplant Recipients
A. W. Rogers¹, T. N. Eagar², C. Pham¹, J. Krisl¹, B. J. Pierce¹, M. Moaddab¹, R. Ghobrial³, B. Trachtenberg⁴, A. Bhimaraj⁴, A. O. Gaber³
¹Department of Pharmacy, Houston Methodist Hospital, Houston, TX, ²Department of Pathology, Houston Methodist Hospital, Houston, TX, ³Department of Surgery, Houston Methodist Hospital, Houston, TX, ⁴Houston Methodist Hospital, Houston, TX
*Purpose: Donor specific antibodies (DSAs) are key in the development of antibody mediated rejection (AMR). Their role in decreased patient and graft survival has been…