ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Ten Year Results of a Single Center Study of Rabbit Anti-Thymocyte Globulin Compared to Alemtuzumab Induction in Simultaneous Pancreas-Kidney Transplantation

    V. Gurram, K. Gurung, G. Orlando, A. Farney, J. Rogers, C. Jay, W. Doares, S. Kaczmorski, A. Reeves-Daniel, A. Mena-Gutierrez, M. Gautreaux, R. Stratta

    Abdominal Transplant Surgery, Wake Forest Baptist Health, Winston Salem, NC

    *Purpose: The study purpose was to analyze 10-year outcomes of depleting antibody induction agents in simultaneous pancreas-kidney transplant (SPKT) at a single center*Methods: From 2/02…
  • 2020 American Transplant Congress

    Use of Donor-Derived Cell-Free DNA Assay to Monitor Treatment Response to Allograft Rejection in Pediatric Renal Transplant Recipients

    J. Steggerda1, H. Phan Pizzo2, J. Garrison2, X. Zhang3, M. Haas4, I. Kim1, S. Jordan1, D. Puliyanda2

    1Comprehensive Transplant Center, Cedars Sinai Medical Center, West Hollywood, CA, 2Pediatric Nephrology, Cedars Sinai Medical Center, West Hollywood, CA, 3HLA Laboratory, Cedars-Sinai Med Center, West Hollywood, CA, 4Pathology, Cedars Sinai Medical Center, West Hollywood, CA

    *Purpose: Acute rejection (AR) accounts for 13%-21% of graft failure in pediatrics (peds), with the number, severity, and response to treatment being a major determinant…
  • 2020 American Transplant Congress

    Human Antigen R (HuR): A New Regulator of Heme Oxygenase-1 Cytoprotection in Mouse and Human Liver Transplantation

    K. J. Dery1, K. Nakamura2, K. Kadono1, H. Hirao1, S. Kageyama1, T. Ito1, H. Kojima1, F. Kaldas1, R. W. Busuttil1, J. W. Kupiec-Weglinski1

    1Department of Surgery, Division of Liver and Pancreas Transplantation, UCLA, Los Angeles, CA, 2Surgery, Nishi-Kobe Medical Center, Hyogo, Japan

    *Purpose: Ischemia-reperfusion injury (IRI) represents a risk factor in liver transplantation (LT). We have shown that overexpression of heme oxygenase 1 (HO-1) mitigates hepatic IRI…
  • 2020 American Transplant Congress

    Bone Marrow Mesenchymal Stem Cells Improve Rat Islet Angiogenesis by Upregulating of ISL1 and VEGF-A

    Y. Wang1, J. Wang2, X. Ding2

    1Department of Renal Transplantation, Nephropathy Hospital, The First Affiliated Hospital of Xi'an Jiaotong University, Xi’an, China, 2Department of Renal Transplantation, Nephropathy Hospital, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China

    *Purpose: Islet transplantation is an important therapy to cure diabetes, but poor angiogenesis in the early stage of islet transplantation is one of the main…
  • 2020 American Transplant Congress

    ABH Subtype-Specific Tolerance after ABO-Mismatched Hematopoietic Cell Transplantation

    B. Motyka1, A. Halpin1, J. Pearcey1, A. Kariminia2, A. Halevy2, S. Maier1, A. Halevy2, P. Subrt2, C. W. Cairo1, G. D. Cuvelier3, K. R. Schultz2, L. J. West1

    1Alberta Transplant Institute, University of Alberta, Edmonton, AB, Canada, 2British Columbia Children’s Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada, 3CancerCare Manitoba, University of Manitoba, Winnipeg, MB, Canada

    *Purpose: ABO-mediated immunity is reported to have minimal detrimental impact after ABO-mismatched hematopoietic cell transplantation (HCT). Patients are generally presumed ‘tolerant’ with regard to ABO.…
  • 2020 American Transplant Congress

    Incidence of Non-Tuberculous Mycobacteria in the Transplant Population at a University Transplant Center in Northern Florida

    D. Schain, Z. Breslow, G. El Helou, A. Cannella

    Medicine/IDGM, Univ of Florida, College of Med, Gainesville, FL

    *Purpose: Over the past decade, there has been an increase in the number of non-tuberculous mycobacteria (NTM) infections in the United States, especially in the…
  • 2020 American Transplant Congress

    Impact of Kidney Allocation System on Waiting List Outcomes for Candidates Listed in Veterans Affairs Programs

    J. Walker1, B. Concepion2, K. Birdwell2, I. Feurer3, S. Rega4, D. Shaffer5, R. Forbes5

    1Surgery, Vanderbilt University Medical Center (VUMC), Nashville, TN, 2Nephrology, VUMC, Nashville, TN, 3Surgery and Biostatistics, VUMC, Nashville, TN, 4Transplant Center, VUMC, Nashville, TN, 5Surgery, Division of Kidney and Pancreas Transplantation, VUMC, Nashville, TN

    *Purpose: Kidney Allocation System (KAS) changes in 2014 prioritized highly sensitized candidates and aimed to improve longevity matching. Given that veterans are older and less…
  • 2020 American Transplant Congress

    Predicting Kidney Discard among Donors Age 0-3: A Discard Risk Index

    M. Joshi, M. Price, A. Rana

    Baylor College of Medicine, Houston, TX

    *Purpose: Among pediatric kidney donors the discard rate is highest among donors under 3-years-old. This study aims to identify factors predicting discard and construct a…
  • 2020 American Transplant Congress

    1 -Year Protocol Biopsies in Pediatric Kidney Transplant Children: Are Unfavorable Histological Lesions Related to No Adherence?

    M. L. Monteverde1, J. M. Velasco1, V. Solernou2, J. P. Ibanez1, C. Cernadas3, A. B. Chaparro4, Y. L. Marcos5

    1Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, 2Pathology, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, 3Teaching and Investigation, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, 4Nephrology, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, 5Hemoteraphy, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina

    *Purpose: In adults with kidney transplantation (KT), histological findings in surveillance biopsies at 1-year post KT are independent correlate to short and long-term graft survival.…
  • 2020 American Transplant Congress

    Tumor of Transplanted Kidney: Graft Resection Preserves Renal Function with Good Long-Term Oncologic Outcome

    J. Chlupac, T. Marada, M. Kudla, L. Janousek, J. Fronek

    Transplantation Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: Incidence of urologic tumors is increased in renal transplant recipients. In case of a kidney transplant neoplasm, the graft-nephrectomy and hemodialysis reduce the quality…
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